DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr11 and Lrit3

DIOPT Version :9

Sequence 1:NP_001262320.1 Gene:dpr11 / 40800 FlyBaseID:FBgn0053202 Length:360 Species:Drosophila melanogaster
Sequence 2:NP_001274153.1 Gene:Lrit3 / 242235 MGIID:2685267 Length:681 Species:Mus musculus


Alignment Length:292 Identity:65/292 - (22%)
Similarity:110/292 - (37%) Gaps:89/292 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    85 DPSSATAFSSLA---------------QVSSLLPEA-------SALSATSG----LVEPYLDGYA 123
            |.:|.|||..::               :::|:..||       :.|..:|.    |...:||.::
Mouse   113 DGNSLTAFPWVSLLDMPHLRTLDLHNNRIASVPNEAVRYLRNLTCLDLSSNRLTTLPPDFLDSWS 177

  Fly   124 TSNVTTQIGTHAYLPCRVKQLGNKSVSWIRLRDGHILTV-------DRAVFIADQRFLAIKQPDK 181
            ...||......  .|.|...||.:...|  ..|.||..|       |.||.:.|. .:...:|::
Mouse   178 HLAVTPSRSPD--FPPRRIILGLQDNPW--FCDCHISKVIELSKVTDHAVVLLDP-LMVCSEPER 237

  Fly   182 YWTLQIKYVQARDAGSYECQVSTEPKVSARVQLQVVVPRTEILGEPDRYVKAGSNVVLRCIVRGA 246
            :..:..:.|:..     :|           ::..|::..|:|..      ..||||:|||..:| 
Mouse   238 FQGILFQRVELE-----KC-----------LKPSVMMSATKITS------ALGSNVLLRCDAKG- 279

  Fly   247 LEPPTFIMWYHGAEQLAADSRRHRTQLDPN------LPEASGEG-QSTIGSLIIESAKKRDTGNY 304
             .|...:.|               |:.|.:      :.|:.||| :.:|.||  .|...:|.|:|
Mouse   280 -HPTPQLTW---------------TRSDGSTVNYTVIQESPGEGIRWSIISL--TSISHKDAGDY 326

  Fly   305 TCSPSN---SPSATVTLNIINGESSASAVTSS 333
            .|...|   ...|.||:.::.|.::..:..||
Mouse   327 RCKAKNLAGISEAVVTVTVVGGVTTTLSPDSS 358

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr11NP_001262320.1 I-set 125..216 CDD:254352 18/97 (19%)
Ig 127..217 CDD:299845 18/96 (19%)
IG_like 227..320 CDD:214653 28/102 (27%)
IGc2 234..311 CDD:197706 25/86 (29%)
Lrit3NP_001274153.1 LRR 1. /evidence=ECO:0000255 56..79
LRR_8 61..117 CDD:290566 1/3 (33%)
LRR 2. /evidence=ECO:0000255 80..103
leucine-rich repeat 83..106 CDD:275378
LRR 3. /evidence=ECO:0000255 104..128 5/14 (36%)
LRR_8 105..165 CDD:290566 10/51 (20%)
LRR_4 106..146 CDD:289563 6/32 (19%)
leucine-rich repeat 107..130 CDD:275378 5/16 (31%)
LRR_4 129..170 CDD:289563 6/40 (15%)
LRR 4. /evidence=ECO:0000255 129..151 3/21 (14%)
leucine-rich repeat 131..154 CDD:275378 3/22 (14%)
LRR 5. /evidence=ECO:0000255 152..175 4/22 (18%)
leucine-rich repeat 155..168 CDD:275378 2/12 (17%)
Ig 254..335 CDD:299845 28/105 (27%)
IG_like 263..339 CDD:214653 26/100 (26%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 350..391 2/9 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 425..464
FN3 489..563 CDD:238020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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