Protein Alignment dpr11 and CADM4

DIOPT Version :10

• Sequence 1: NP_788586.1
• Gene: dpr11 / 40800
• FlyBaseID: FBgn0053202
• Length: 360
• Species: Drosophila melanogaster
• Sequence 2: NP_660339.1
• Gene: CADM4 / 199731
• HGNCID: 30825
• Length: 388
• Species: Homo sapiens
• Alignment Length: 349
• Identity: 73/349 - (20%)
• Similarity: 106/349 - (30%)
• Gaps: 149/349 - (42%)

  Fly   124 TSNVTTQIGTHAYLPCRVKQLGNKSVSWIRLRDGHILTVD----RAVF------IADQRFLAIKQ 178
            |.|||...|..|.:.||:.|.           ||.|:.:.    :.:|      :.|:||...:.
Human    29 TENVTVAEGGVAEITCRLHQY-----------DGSIVVIQNPARQTLFFNGTRALKDERFQLEEF 82

  Fly   179 PDKYWTLQIKYVQARDAGSYECQVSTE-----------------PKVSAR--------VQLQVVV 218
            ..:...:::...:..|.|.|.||:.||                 |.|..|        |:|..:|
Human    83 SPRRVRIRLSDARLEDEGGYFCQLYTEDTHHQIATLTVLVAPENPVVEVREQAVEGGEVELSCLV 147

  Fly   219 PRT-------------EILG-------------------EPDR---------------------- 229
            ||:             |:.|                   ..||
Human   148 PRSRPAATLRWYRDRKELKGVSSSQENGKVWSVASTVRFRVDRKDDGGIIICEAQNQALPSGHSK 212

  Fly   230 ---------------------YVKAGSNVVLRCIVRGALEP-PTFIMWYHGAEQLAADSRRHRTQ 272
                                 .|:.|..:||.|.|.|  .| |..|.|..|.|.|
Human   213 QTQYVLDVQYSPTARIHASQAVVREGDTLVLTCAVTG--NPRPNQIRWNRGNESL---------- 265

  Fly   273 LDPNLPEASGEGQSTIGSLIIESAKKRDTGNYTCSPSNSPSATVTLNIINGESSASAVTSSAATT 337
              |...||.||      :|.:......|.|.|||..||.......|.::......:.|  .|.|:
Human   266 --PERAEAVGE------TLTLPGLVSADNGTYTCEASNKHGHARALYVLVVYDPGAVV--EAQTS 320

  Fly   338 RAYA-----LSILALLLSVILIGV 356
            ..||     |::|..|:..:|:|:
Human   321 VPYAIVGGILALLVFLIICVLVGM 344

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpr11	NP_788586.1	Ig	125..216	CDD:472250	27/125 (22%)
		Ig strand B	135..139	CDD:409353	1/3 (33%)
		Ig strand C	148..152	CDD:409353	0/3 (0%)
		Ig strand E	183..187	CDD:409353	0/3 (0%)
		Ig strand F	197..202	CDD:409353	2/4 (50%)
		IG_like	227..320	CDD:214653	30/136 (22%)
		Ig strand B	237..241	CDD:409544	2/3 (67%)
		Ig strand C	252..256	CDD:409544	1/3 (33%)
		Ig strand E	289..293	CDD:409544	1/3 (33%)
		Ig strand G	313..316	CDD:409544	0/2 (0%)
CADM4	NP_660339.1	Ig	29..120	CDD:472250	23/101 (23%)
		Ig strand B	40..44	CDD:409353	1/3 (33%)
		Ig strand C	53..57	CDD:409353	1/3 (33%)
		Ig strand E	87..91	CDD:409353	0/3 (0%)
		Ig strand F	101..106	CDD:409353	2/4 (50%)
		Ig strand G	113..116	CDD:409353	0/2 (0%)
		IgI_2_Necl-4	121..220	CDD:409468	12/98 (12%)
		Ig strand A	121..124	CDD:409468	0/2 (0%)
		Ig strand A'	127..131	CDD:409468	2/3 (67%)
		Ig strand B	139..149	CDD:409468	3/9 (33%)
		Ig strand C	152..161	CDD:409468	0/8 (0%)
		Ig strand C'	162..165	CDD:409468	0/2 (0%)
		Ig strand D	167..174	CDD:409468	1/6 (17%)
		Ig strand E	177..187	CDD:409468	0/9 (0%)
		Ig strand F	195..203	CDD:409468	0/7 (0%)
		Ig strand G	212..219	CDD:409468	0/6 (0%)
		Ig_3	224..295	CDD:464046	25/90 (28%)
		4.1m	344..362	CDD:128590	0/1 (0%)