DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr11 and rig-3

DIOPT Version :9

Sequence 1:	NP_001262320.1	Gene:	dpr11 / 40800	FlyBaseID:	FBgn0053202	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	NP_509155.1	Gene:	rig-3 / 180958	WormBaseID:	WBGene00004370	Length:	487	Species:	Caenorhabditis elegans

Alignment Length:	203	Identity:	40/203 - (19%)
Similarity:	70/203 - (34%)	Gaps:	50/203 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 LSATSGLVEPYLDGYATSNVTTQIGTHAYLPCRVKQLGNKSVSWIRLRDGHILTVDRAVFIADQR 172
            :..|:|..|| ||    ..:.|..|..|.:....|:....:||.|        |::.....:.:.
Worm   179 IQMTNGNGEP-LD----EEIWTIAGNEATIDSLKKEHAELTVSCI--------TIEMHQETSKEE 230

  Fly   173 FLAIKQPDKYWTLQIKYVQARDAGSYECQVSTEPKVSARVQLQVVVPRTEILGEPDRYVKAGSNV 237
            |..:.:.|                 ...:|.|.|:......:|..|        .|.:|:   :.
Worm   231 FPVVDRKD-----------------VNIEVYTLPEFETEESVQYTV--------IDNHVR---DA 267

  Fly   238 VLRCIVRGALEPPTFIMWYHGAEQLAADSRRHRTQLDPNLPEASGEGQSTIGSLIIESAKKRDTG 302
            ::.|.|..:..|.....:|||.|::....   :..:..|:      |.|....|.|.:..:.|.|
Worm   268 IIYCNVTHSFPPVRHYTFYHGDEEIKMSD---KFNIFVNV------GVSQGAHLKIHNVNENDLG 323

  Fly   303 NYTCSPSN 310
            .|.|..:|
Worm   324 TYKCEANN 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr11	NP_001262320.1	I-set	125..216	CDD:254352	13/90 (14%)
		Ig	127..217	CDD:299845	14/89 (16%)
		IG_like	227..320	CDD:214653	19/84 (23%)
		IGc2	234..311	CDD:197706	17/77 (22%)
rig-3	NP_509155.1	IG_like	48..142	CDD:214653
rig-3	NP_509155.1	Ig	267..341	CDD:319273	17/74 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900