DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr11 and igcm-2

DIOPT Version :9

Sequence 1:	NP_001262320.1	Gene:	dpr11 / 40800	FlyBaseID:	FBgn0053202	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	NP_001362087.1	Gene:	igcm-2 / 180913	WormBaseID:	WBGene00020130	Length:	802	Species:	Caenorhabditis elegans

Alignment Length:	239	Identity:	56/239 - (23%)
Similarity:	89/239 - (37%)	Gaps:	64/239 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   132 GTHAYLPCRVKQLGNKSVSWIRLRDGHILTVDRAVFIADQRFLAIKQP--------DKYWTLQIK 188
            |....|||.:.....:|.|....:||.::.   :.|..:|..:.   |        |.:..:.|.
Worm    28 GAPITLPCSISLFNEESFSLDWRKDGQLIL---SAFGQEQGHVT---PTLQGRLARDGFLGITIH 86

  Fly   189 YVQARDAGSYECQVS------TEPKVSARVQLQVVVPRTEILGEPDR----YVKAGSNVVLRCIV 243
            .|...|||.|:|.|:      |.|:.....:|.|.||  .::..|.:    :.|.|::::..|..
Worm    87 SVTDGDAGVYQCIVTKFSKQPTRPEKGLSAKLVVNVP--PVIISPSKNAIIHKKVGADLIFECKA 149

  Fly   244 RGALEPPTFIMWYHGAEQLAADSRRHRTQLDPNLPEASGEGQSTIGSLIIESAKKRDTGNYTCSP 308
            .||..|.  |.|... ||:.                      ||...|.:.:.::.|.|.|||..
Worm   150 EGAPSPE--ITWSRN-EQII----------------------STSPVLTLSNLEEGDKGLYTCLA 189

  Fly   309 SNSPSATVTLNIINGESSASAVTSSAATTRAYALSILALLLSVI 352
            .|          |.|.|::|.   ....|:|..|.::.|..:||
Worm   190 VN----------IEGNSTSSI---DVRFTKATILDLIPLNKTVI 220

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr11	NP_001262320.1	I-set	125..216	CDD:254352	23/97 (24%)
		Ig	127..217	CDD:299845	23/98 (23%)
		IG_like	227..320	CDD:214653	20/96 (21%)
		IGc2	234..311	CDD:197706	17/76 (22%)
igcm-2	NP_001362087.1	IG_like	23..101	CDD:214653	19/78 (24%)
		Ig	124..200	CDD:386229	23/110 (21%)
		IG_like	214..298	CDD:214653	3/7 (43%)
		Ig_3	309..371	CDD:372822
		Ig	389..467	CDD:386229
		FN3	476..548	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900