DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr11 and Ncam1

DIOPT Version :9

Sequence 1:	NP_001262320.1	Gene:	dpr11 / 40800	FlyBaseID:	FBgn0053202	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	XP_006510118.1	Gene:	Ncam1 / 17967	MGIID:	97281	Length:	1162	Species:	Mus musculus

Alignment Length:	180	Identity:	45/180 - (25%)
Similarity:	68/180 - (37%)	Gaps:	27/180 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   131 IGTHAYLPCRVK-QLGNKSVSWIRLRDGHILTVDRAVFIADQRFLAIKQPDKYWTLQIKYVQARD 194
            :|...:..|:|. ...:|.:||.. .:|..|:.::      ||...:...|...||.|......|
Mouse    33 VGESKFFLCQVAGDAKDKDISWFS-PNGEKLSPNQ------QRISVVWNDDDSSTLTIYNANIDD 90

  Fly   195 AGSYECQVSTEPKVSARVQLQVVVPRTEILGE---PDRYVKAGSNVVLRCIVRGALEPPTFIMWY 256
            ||.|:|.|:.|....:...:.|.:.:..:...   |..: |.|.:.|:.|.|..:| ||| |:|.
Mouse    91 AGIYKCVVTAEDGTQSEATVNVKIFQKLMFKNAPTPQEF-KEGEDAVIVCDVVSSL-PPT-IIWK 152

  Fly   257 HGAEQLAADSRRHRTQLDPNLPEASGEGQSTIGSLIIESAKKRDTGNYTC 306
            |....:..........|..|.             |.|...||.|.|.|.|
Mouse   153 HKGRDVILKKDVRFIVLSNNY-------------LQIRGIKKTDEGTYRC 189

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr11	NP_001262320.1	I-set	125..216	CDD:254352	21/85 (25%)
		Ig	127..217	CDD:299845	21/86 (24%)
		IG_like	227..320	CDD:214653	23/80 (29%)
		IGc2	234..311	CDD:197706	21/73 (29%)
Ncam1	XP_006510118.1	Ig1_NCAM-1	20..115	CDD:143273	22/88 (25%)
		IG	124..190	CDD:214652	23/82 (28%)
		Ig3_NCAM-1_like	211..308	CDD:143207
		Ig_NCAM-1	307..413	CDD:143277
		Ig_3	417..494	CDD:372822
		FN3	509..606	CDD:238020
		fn3	649..731	CDD:365830
		PHA03247	<905..1140	CDD:223021
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900