DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr11 and Kirrel

DIOPT Version :9

Sequence 1:	NP_001262320.1	Gene:	dpr11 / 40800	FlyBaseID:	FBgn0053202	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	XP_011238330.1	Gene:	Kirrel / 170643	MGIID:	1891396	Length:	805	Species:	Mus musculus

Alignment Length:	275	Identity:	78/275 - (28%)
Similarity:	111/275 - (40%)	Gaps:	68/275 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 SSLLPE----------------ASALSATSGLVEPYLDGYAT------SNVTTQIGTHAYLPCRV 141
            ||||||                |..:..|..|..|   |..|      ::.|...|..|.|||
Mouse    15 SSLLPEKPRFLSQKMWAPHLVVAYLIFVTLALALP---GTQTRFSQEPADQTVVAGQRAVLPC-- 74

  Fly   142 KQLGNKS--VSWIRLRDGHILTVDRAVFIADQRFLAIKQPDK-YWTLQIKYVQARDAGSYECQVS 203
             .|.|.|  |.|  .:||..|.:.:.: .|..|:..:...|. .:.|:|...:..|..|||||.:
Mouse    75 -VLLNYSGIVQW--TKDGLALGMGQGL-KAWPRYRVVGSADAGQYNLEITDAELSDDASYECQAT 135

  Fly   204 TEPKVSARVQLQVVVP--RTEILGEPDRYVKAGSNVVLRCIVRGALEPPTFIMWYH-GAEQLAAD 265
            .....|.|.:|.|::|  .|.|.|.|...::||:...|.|....| :|...|:|:. |.:|..|.
Mouse   136 EAALRSRRAKLTVLIPPEETRIDGGPVILLQAGTPYNLTCRAFNA-KPAATIIWFRDGTQQEGAV 199

  Fly   266 SRRHRTQLDPNLPEASGEGQSTIGSLIIESAKKRDTGN-YTCSPSNS--PSA------------- 314
            :   .|:|     ...|:.::||..|:||.. ..|.|. :||...|.  |:.
Mouse   200 T---STEL-----LKDGKRETTISQLLIEPT-DLDIGRVFTCRSMNEAIPNGKETSIELDVHHPP 255

  Fly   315 TVTLNI-----INGE 324
            ||||:|     :.||
Mouse   256 TVTLSIEPQTVLEGE 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr11	NP_001262320.1	I-set	125..216	CDD:254352	28/93 (30%)
		Ig	127..217	CDD:299845	28/92 (30%)
		IG_like	227..320	CDD:214653	30/109 (28%)
		IGc2	234..311	CDD:197706	22/78 (28%)
Kirrel	XP_011238330.1	Ig	54..148	CDD:386229	28/99 (28%)
		Ig2_KIRREL3-like	170..251	CDD:143236	23/90 (26%)
		Ig	255..336	CDD:386229	7/16 (44%)
		Ig_3	340..421	CDD:372822
		Ig5_KIRREL3	439..536	CDD:143306
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810