DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr11 and si:ch211-264f5.6

DIOPT Version :9

Sequence 1:	NP_001262320.1	Gene:	dpr11 / 40800	FlyBaseID:	FBgn0053202	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	XP_002665524.2	Gene:	si:ch211-264f5.6 / 100319064	ZFINID:	ZDB-GENE-081104-208	Length:	540	Species:	Danio rerio

Alignment Length:	348	Identity:	75/348 - (21%)
Similarity:	130/348 - (37%)	Gaps:	84/348 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 TQLLLGGILCLTIASHTQTSA---------EAAGGRVSGPGAGTSEG-AGTSSASAASTAISSDE 82
            |.|..|..|.||..:.:...|         ......||.|...|... ...:|.:....|.::..
Zfish   238 TYLKKGSTLTLTCTADSNPPATIQWVFNGVNLPSNAVSSPANFTLNNLEEKNSGNYTCVAYNAQT 302

  Fly    83 SGDPSSATAFSSLAQVSSLLPEASALSATSGLVEPYLDGYATSNVTTQIGTHAYLPCRVKQLGNK 147
            ....:|..||.::  |.||  ..:.:|:::.|:   :.|.:|.|:|          |.......:
Zfish   303 KRYIASRVAFVTV--VESL--SGTNISSSTSLL---IAGNSTVNLT----------CFAAAGRAE 350

  Fly   148 SVSWIRLRDGHILTVD-RAVFIADQRFLAIKQPDKYWTLQIKYVQARDAGSYECQVSTE-PKVSA 210
            :|.|:  :||..|..| |.||.||:..::|   ||        |...|.|.|.|.:..: .|..|
Zfish   351 TVEWV--KDGKPLNPDSRIVFSADKTSVSI---DK--------VVKEDRGEYRCLLRNKVNKDEA 402

  Fly   211 RVQLQVVVPRTEILGEPDRYVKAGSNVVLRCIVRGALEPPTFIMWYHGAEQLAADSRRHRTQLDP 275
            ...|::.....::..:....||...:|.|.|.....  ||:...|......|.:..:.:
Zfish   403 SYNLKINYGPEKVAVQGKHAVKFEDDVELSCTAESV--PPSTYTWKLNGTALNSSQQVY------ 459

  Fly   276 NLPEASGEGQSTIGSLIIESAKKRDTGNYTCSPSNSPSATVTLNIINGESSAS----AVTS---- 332
                            :::.||.||:|.|||...|:         |.|:...:    |||:
Zfish   460 ----------------VVKRAKDRDSGIYTCEAFNN---------ITGKMDKTTHKLAVTTDGKE 499

  Fly   333 -SAATTRAYALSILALLLSVILI 354
             :..:..|.|..::.:::::|:|
Zfish   500 DTGLSGGAIAGIVIGVIVAIIII 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr11	NP_001262320.1	I-set	125..216	CDD:254352	25/92 (27%)
		Ig	127..217	CDD:299845	24/91 (26%)
		IG_like	227..320	CDD:214653	18/92 (20%)
		IGc2	234..311	CDD:197706	15/76 (20%)
si:ch211-264f5.6	XP_002665524.2	Ig	33..129	CDD:299845
		IG_like	33..128	CDD:214653
		Ig	130..222	CDD:299845
		IG_like	149..222	CDD:214653
		I-set	233..315	CDD:254352	16/76 (21%)
		Ig_2	235..315	CDD:290606	16/76 (21%)
		IGc2	335..398	CDD:197706	23/85 (27%)
		Ig_2	427..494	CDD:290606	19/99 (19%)
		IG_like	427..479	CDD:214653	15/75 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910