DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr11 and negr1

DIOPT Version :9

Sequence 1:NP_001262320.1 Gene:dpr11 / 40800 FlyBaseID:FBgn0053202 Length:360 Species:Drosophila melanogaster
Sequence 2:XP_031755650.1 Gene:negr1 / 100127726 XenbaseID:XB-GENE-987949 Length:388 Species:Xenopus tropicalis


Alignment Length:316 Identity:73/316 - (23%)
Similarity:108/316 - (34%) Gaps:116/316 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly   123 ATSNVTTQIGTHAYLPCRVKQLGNKSVSWIR-----LRDGHILTVDRAVFIADQRFLAIKQPDKY 182
            |..|:..:.|..|.|.|.:::..:|. :|:.     ...|...:||..|.||    .:.||.   
 Frog    45 AVDNLVVRQGETAMLRCFLEEGASKG-AWLNRSSIIFAGGDKWSVDPRVSIA----TSSKQE--- 101

  Fly   183 WTLQIKYVQARDAGSYECQVSTE--PKVSARVQLQV-VVPRTEILGEPDRYVKAGSNVVLRCIVR 244
            ::|:|:.|...|.|.|.|.|.||  |: :.:|.|.| |.|:...:.. |..|..|:||.|.|:..
 Frog   102 YSLRIQKVDVSDDGPYTCSVQTEHSPR-TLQVHLTVHVSPKIYDISS-DMTVNEGTNVSLICLAT 164

  Fly   245 GALEP--------------------------------------------------------PTFI 253
            |..||                                                        ||.:
 Frog   165 GKPEPSISWRHISPSAKQFGSGQYLDIYGITRDQAGDYECSAENDVSFPDVKKVKVTVNFAPTIL 229

  Fly   254 ---------------------------MWYHGAEQLAADSRRHRTQLDPNLPEASGEGQSTIGSL 291
                                       .||.|.::|....|..|.|           ..:|...|
 Frog   230 EITPTGVSLGRTGLIRCETAAVPAPVFEWYKGEKKLTNGQRGIRIQ-----------NYNTRSIL 283

  Fly   292 IIESAKKRDTGNYTCSPSN---SPSATVTLNIINGESSASAVTSSAA-TTRAYALS 343
            .:.:..:...|||||...|   :.:|::.||.|...|:.|.|||||. :.:.||.|
 Frog   284 TVSNVTEEHFGNYTCVAVNKLGTSNASLPLNQIIEPSTTSPVTSSAKYSVKHYARS 339

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr11NP_001262320.1 I-set 125..216 CDD:254352 28/97 (29%)
Ig 127..217 CDD:299845 28/97 (29%)
IG_like 227..320 CDD:214653 29/178 (16%)
IGc2 234..311 CDD:197706 25/162 (15%)
negr1XP_031755650.1 Ig 44..136 CDD:416386 29/99 (29%)
FR1 44..62 CDD:409353 5/16 (31%)
Ig strand A' 47..53 CDD:409353 1/5 (20%)
Ig strand B 55..63 CDD:409353 3/7 (43%)
CDR1 63..68 CDD:409353 0/4 (0%)
FR2 69..75 CDD:409353 2/6 (33%)
Ig strand C 69..74 CDD:409353 2/5 (40%)
CDR2 76..87 CDD:409353 1/10 (10%)
Ig strand C' 78..82 CDD:409353 0/3 (0%)
Ig strand C' 84..87 CDD:409353 0/2 (0%)
FR3 88..122 CDD:409353 14/40 (35%)
Ig strand D 91..98 CDD:409353 3/10 (30%)
Ig strand E 101..107 CDD:409353 1/8 (13%)
Ig strand F 114..122 CDD:409353 3/7 (43%)
CDR3 123..127 CDD:409353 2/3 (67%)
Ig strand G 127..136 CDD:409353 3/9 (33%)
FR4 129..136 CDD:409353 2/6 (33%)
Ig_3 140..208 CDD:404760 11/68 (16%)
Ig strand A' 146..151 CDD:409353 1/5 (20%)
Ig strand B 157..164 CDD:409353 3/6 (50%)
Ig strand C 170..175 CDD:409353 0/4 (0%)
Ig strand C' 177..179 CDD:409353 0/1 (0%)
Ig strand E 187..193 CDD:409353 0/5 (0%)
Ig strand F 200..207 CDD:409353 0/6 (0%)
Ig strand G 214..222 CDD:409353 0/7 (0%)
Ig_3 226..302 CDD:404760 16/86 (19%)
putative Ig strand A 226..232 CDD:409353 2/5 (40%)
Ig strand B 242..246 CDD:409353 0/3 (0%)
Ig strand C 255..259 CDD:409353 0/3 (0%)
Ig strand E 281..285 CDD:409353 1/3 (33%)
Ig strand F 295..300 CDD:409353 4/4 (100%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 46 1.000 Domainoid score I11916
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.000

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