Protein Alignment Neurochondrin and Neurochondrin

DIOPT Version :10

• Sequence 1: NP_649658.1
• Gene: Neurochondrin / 40796
• FlyBaseID: FBgn0037447
• Length: 723
• Species: Drosophila melanogaster
• Sequence 2: XP_003436800.1
• Gene: Neurochondrin / 11175688
• VectorBaseID: AGAMI1_002704
• Length: 733
• Species: Anopheles gambiae
• Alignment Length: 730
• Identity: 456/730 - (62%)
• Similarity: 576/730 - (78%)
• Gaps: 9/730 - (1%)

  Fly     3 DVPEPVRKCASLLKGTKSDTEKFAALFMVTKLVKGKDCNAAGKKLLFEAIGFPFLKKLLVSKDLP 67
            :|.||::||:.:||..||||||||||||||||:||||||.|||:||||:|||.||:|||.|||:|
Mosquito     4 EVSEPIKKCSLILKNAKSDTEKFAALFMVTKLIKGKDCNQAGKRLLFESIGFDFLRKLLTSKDVP 68

  Fly    68 NDCPPLVYKSVALSILTCFCQEEELATHKDIIDAIPTLLEIVEQADDEDYEDNLIVVSEAYSCLK 132
            :|||..||:|||||||:|||.:|:||||:|::|:||..:.||...||::|:||||:::|||.||:
Mosquito    69 DDCPASVYQSVALSILSCFCDDEQLATHQDMLDSIPVFMGIVSTCDDDEYDDNLIIINEAYHCLQ 133

  Fly   133 SIASHEPGQQALLATGAIPKMSQIYSAQSFQTDEALHLIVLLVKQFGVVSWPEDPTAFHALIQRI 197
            ||:.:|.|:.||.....|.||:|||:.:|||.||||.|||.||.:||..||..||..||||:||:
Mosquito   134 SISLYESGRLALRQHDVITKMAQIYTQRSFQIDEALTLIVTLVARFGANSWDNDPKLFHALLQRV 198

  Fly   198 ALDMETDDTERKYELCRILADILITCRREIVINSLEGQIWPESLFKGCGDILKAKIGPKQRDPAL 262
            :||.|||..|||:||..:::.:|..|||::|..:::|:||||.|:||..||||:|||..||||||
Mosquito   199 SLDFETDHAERKFELAEMISSLLFHCRRDLVARTVQGEIWPECLYKGISDILKSKIGKAQRDPAL 263

  Fly   263 HLIATTLHVLGIQWAFMDEQ--KTFFLQLLQLGAIEVRMQMDEKKLETTFKQAELLTCCFSILEH 325
            .|.|..:.||||:|...|.:  |.|||.||||.|||||||||.|......:||:|:|.||.|||.
Mosquito   264 KLAANAVDVLGIEWTLHDVENPKKFFLLLLQLAAIEVRMQMDNKSFNQCVQQADLITACFIILEL 328

  Fly   326 CIEYMATDQLDLEPKEKQTTYTALKGAFNQVLAVLTRVSQDKIRESSNPKDKKFVFAIVKVLSAW 390
            .|.:|:||||||:.|:||..||.|||||:.||.||.:::.|..::.....:|.|.:|:|:||:||
Mosquito   329 SINFMSTDQLDLDQKDKQQVYTGLKGAFSAVLGVLVKLANDTKKDRLQKTEKAFAYAMVRVLTAW 393

  Fly   391 LAQETTAMRPAIYKLLPFMLKVANESFQELKTWRAGTR-------EGEPPIDVLRIMLPALCHFA 448
            |||||:||:..:.|:|||:.|:|||||.|.:.:|...:       |.:||.|:||:||||:||..
Mosquito   394 LAQETSAMKNQVSKVLPFLFKLANESFYESRDYRIAHKADNVDDHEQQPPADILRVMLPAICHLV 458

  Fly   449 VEEEARRVLFTHKQDEVLLESLEFYFSIAHWKRPPIPRAERLKRMNEPDPVPTPEQQAEMKVARS 513
            ||||||::....|:::||.:.|.|::||||:|:||:||||||||||||||..||:|..:||.:|:
Mosquito   459 VEEEARQIFLKEKEEQVLYDCLLFHWSIAHYKKPPVPRAERLKRMNEPDPEMTPQQLDDMKDSRT 523

  Fly   514 AIVALCNILMNFTVLEPKKAEDGPTFANLLKFVVENLPELKDTPDNLVIHGNLAVLGLLLLKQQS 578
            |||:|||||||.||||.|..|:...||.||:|:.||||||||.|||||:||:||||||||||||:
Mosquito   524 AIVSLCNILMNITVLEAKLVEESTLFAQLLRFIFENLPELKDIPDNLVMHGHLAVLGLLLLKQQA 588

  Fly   579 KKVKQNDFSICRYIQATIRFLWDAYNIDESNDPTALVVSIAYKGYWSDLSELWFLGMQTMCGVLP 643
            .|:|:||||||||||.|||||||||||||||||.|||||:.||.:|.::.||||||||||.|::.
Mosquito   589 SKIKKNDFSICRYIQTTIRFLWDAYNIDESNDPQALVVSMQYKEHWFEIMELWFLGMQTMSGIIK 653

  Fly   644 LVPWLSEFALESGWAEGIVKTLKKVKIGTLPANVKSAYEDFLSQLVDVNGDVQAVLKKADALRVC 708
            |:||:||||:|||||||||:||:||||||||.|||.|||||||||||.|..|..||||||||:||
Mosquito   654 LIPWISEFAIESGWAEGIVETLRKVKIGTLPPNVKLAYEDFLSQLVDANPAVAPVLKKADALKVC 718

  Fly   709 RNHRMMDLGKKLFGD 723
            |||||||||||||||
Mosquito   719 RNHRMMDLGKKLFGD 733

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Neurochondrin	NP_649658.1	Neurochondrin	2..631	CDD:336138	379/636 (60%)
Neurochondrin	XP_003436800.1	Neurochondrin	3..641	CDD:336138	388/645 (60%)