Protein Alignment Neurochondrin and ncdn

DIOPT Version :9

• Sequence 1: NP_649658.1
• Gene: Neurochondrin / 40796
• FlyBaseID: FBgn0037447
• Length: 723
• Species: Drosophila melanogaster
• Sequence 2: XP_002938879.1
• Gene: ncdn / 100494451
• XenbaseID: XB-GENE-968620
• Length: 720
• Species: Xenopus tropicalis
• Alignment Length: 723
• Identity: 197/723 - (27%)
• Similarity: 356/723 - (49%)
• Gaps: 60/723 - (8%)

  Fly     3 DVPEP-VRKCASLLKGTKSDTEKFAALFMVTKLVKGKDCNAAGKKLLFEAIGFPFLKKLLVSKDL 66
            :|..| :.||..:|||.::|:|:||||.:|||..:.::.|...::.:|:|:||.|..:||.|..:
 Frog    11 EVKNPALEKCLEVLKGAQTDSEQFAALLLVTKCAQAEELNNEMRRTIFDAVGFTFPNRLLFSSSV 75

  Fly    67 PNDCPPLVYKSVALSILTCFCQEEELATHKDIIDAIPTLLEIVEQADDEDYEDNLIVVSEAYSCL 131
            |:.||..:::|:.:::|.|||.:..||.|..:|:.||...|.|........::.:.:|.:||.||
 Frog    76 PDGCPSHLFRSLGVTLLACFCTDPALAVHPQVINKIPIFNETVNTPCQSGNKELVSMVEDAYQCL 140

  Fly   132 KSIASHEPGQQALLATGAIPKMSQIYSAQSFQTDEALHLIVLLVKQFGVVSWPEDPTAFHALIQR 196
            ..|.:...|.:.|::.|::|.:.|.|..::...::||.::..|:.......|.:..|....|:.|
 Frog   141 LGILASPQGAKNLISHGSLPCLCQAYLNRNHCWEKALQILTSLLTVLPTKCWKKSCTDLQLLLTR 205

  Fly   197 IALDMETDDTERKYELCRILADILITCRREIVINSLEGQIWPESLFKGCGDILKAKIGPKQRDPA 261
            ::.:...::.|||::|..:|...|...  .:::.:..|:...:.|.||...||..|:...|||||
 Frog   206 LSEEFSKEEGERKFQLVDLLPAFLPPL--PVLLETSWGEECLKQLCKGLLKILSNKLSISQRDPA 268

  Fly   262 LHLIATTLHVLGIQWAFMD---EQKTFFLQLLQLGAIEVRMQMDEKKLETTFKQAELLTCCFSIL 323
            |.|.|...:..|..|..::   |:..|...::.|..:||||.:::.: ..|.:|:. :|.|::::
 Frog   269 LKLGACLANAYGSSWIIVENKVERSRFLALIVNLACVEVRMALEDPE-PLTSRQSS-ITACYALV 331

  Fly   324 EHCIEYMATDQLDLEPKEKQTTYTALKGAFNQVLAVLTRVSQDKIRESSNPKDKKFVFAIVKVLS 388
            |..|:  |..:.:..|...|.....|.|...:..|.:....|....|.   ::..|:.|.:::|.
 Frog   332 EMGIQ--ACTKEEKRPVLGQEQKLQLIGVMQEACASIIHYLQQFGWEM---QEDPFLLASIRLLG 391

  Fly   389 AWLAQETTAMRPAIYKLLPFMLKVANESFQELKTWRAGTREGEP------------PIDVLRIML 441
            ||||:||..::..:.||||:::.......|.....|...:|...            |.|.:|.:|
 Frog   392 AWLAEETACLKLEVIKLLPYLVHYMRTCHQRSVICRNLPKEVSQVALLSCSWGTIWPGDAIRFLL 456

  Fly   442 PALCHFAVEEEARRVLFTHKQDEVLLESLEFYFSIAHWKRPPIPRAERLKRMNEPDPVPTPEQQA 506
            |||||.:.||..|:||.:.....:|.:    ||. ..|        :.|...:||:.:   :..|
 Frog   457 PALCHLSAEEAPRKVLISEGVPVLLCD----YFQ-QQW--------DVLFAEDEPEGM---QSAA 505

  Fly   507 EMKVARSAIVALCNILMNFTVLEPKKAEDGPTFANLLKFVVENLPELKDTPDNLVIHGNLAVLGL 571
            |:     ::...|.:.:|..|.||.......:|..|||.:::.||.|.....:||:..|.|.|||
 Frog   506 EL-----SLQTCCGVFLNLVVTEPTLVGQESSFVLLLKHLMQCLPTLLTKEGHLVLVANFATLGL 565

  Fly   572 LLLKQQSKKVKQNDFSICRYIQATIRFLWDAYNIDESNDPT--------ALVVSIAYKGYWSDLS 628
            ::.:..::....::.:...:.:|||.||      ..|:.|:        .:::|.:|...|.::|
 Frog   566 MMSRLLAENSVLHESNSQEFFKATIHFL------SHSHVPSCQTDAGKPVIMLSESYAEAWEEIS 624

  Fly   629 ELWFLGMQTMCGVLPLVPWLSEFALESGWAEGIVKTLKKVKIGTLPANVKSAYEDFLSQLVDVNG 693
            ||||||:|.....:.|:||||...|.|||.:..:..|..|...::.:::.:|.:..|.:|...|.
 Frog   625 ELWFLGVQAFSNCVHLLPWLSTLVLSSGWLQESLCLLDNVSPKSVDSDLVTALQGMLIELAQSNS 689

  Fly   694 DVQAVLKK 701
            ..:.|::|
 Frog   690 LCRDVIRK 697

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Neurochondrin	NP_649658.1	Neurochondrin	2..631	CDD:283244	174/651 (27%)
ncdn	XP_002938879.1	Neurochondrin	13..627	CDD:336138	173/649 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	251	1.000	Domainoid score	I2059
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8064
Inparanoid	1	1.050	288	1.000	Inparanoid score	I2766
OMA	1	1.010	-	-		QHG49523
OrthoDB	1	1.010	-	-		D157138at33208
OrthoFinder	1	1.000	-	-		FOG0007454
OrthoInspector	1	1.000	-	-		oto102253
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4680
SonicParanoid	1	1.000	-	-		X6328
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.010