DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zif and TT1

DIOPT Version :9

Sequence 1:	NP_001189188.1	Gene:	Zif / 40795	FlyBaseID:	FBgn0037446	Length:	388	Species:	Drosophila melanogaster
Sequence 2:	NP_174737.2	Gene:	TT1 / 840386	AraportID:	AT1G34790	Length:	303	Species:	Arabidopsis thaliana

Alignment Length:	295	Identity:	60/295 - (20%)
Similarity:	101/295 - (34%)	Gaps:	85/295 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   116 MYILEETTTGEEEHQEEKGHEEYLEV-DTSDQQECIGDT-------IEYLEDNYTIEMNSDQTEI 172
            :|.:..:::.|    :.:.|.:.|:: ...:|..||.:|       |:.:..|..:::|.:  .:
plant     6 LYEISSSSSSE----KPRHHFQSLDLFPNLNQNSCINNTLIEPLPLIDRINLNSNLDLNPN--PL 64

  Fly   173 VLESEKQYEETPSQQ---------LALQEAAKASLKARRGRVRRGLNSLTTSDG----TEKGG-- 222
            ..|..:|.||...::         :.|....|.|..|::.:.|.|....|...|    .|..|
plant    65 YAEEGEQEEEEEEEEDREVDVDLHIGLPGFGKPSNDAKQLKKRNGKEIATYDAGKGIENELSGKA 129

  Fly   223 ---------------YICDVCGNFYEKRGRMMEHRRRHD-------------------GICQYAC 253
                           :.|.||...:.:...:..|...|.                   ||..|.|
plant   130 YWIPAPEQILIGFTHFSCHVCFKTFNRYNNLQMHMWGHGSQYRKGPESLKGTQPRAMLGIPCYCC 194

  Fly   254 ELCDAKFQVREQLRKHMYSHTGSKPYKCSFCSRQFFYESVLKSHENVHRGIKPYVCKVCDKAFAY 318
            .         |..|.|: .|..|||.|      .|   ..|::|.....|.||:.|::|.|..|.
plant   195 V---------EGCRNHI-DHPRSKPLK------DF---RTLQTHYKRKHGHKPFSCRLCGKLLAV 240

  Fly   319 AHSLTKHELIHSDIKLYRCDYCNKDFRLLHHMRQH 353
            ......||  .:..|.:.| .|..||:....::.|
plant   241 KGDWRTHE--KNCGKRWVC-VCGSDFKHKRSLKDH 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zif	NP_001189188.1	zf-AD	9..87	CDD:285071
		C2H2 Zn finger	225..245	CDD:275368	4/19 (21%)
		COG5048	<250..369	CDD:227381	28/104 (27%)
		C2H2 Zn finger	253..273	CDD:275368	4/19 (21%)
		zf-H2C2_2	266..288	CDD:290200	7/21 (33%)
		C2H2 Zn finger	281..301	CDD:275368	3/19 (16%)
		zf-H2C2_2	294..318	CDD:290200	8/23 (35%)
		C2H2 Zn finger	309..329	CDD:275368	6/19 (32%)
		C2H2 Zn finger	337..353	CDD:275368	4/15 (27%)
TT1	NP_174737.2	C2H2 Zn finger	231..247	CDD:275368	4/15 (27%)
TT1	NP_174737.2	C2H2 Zn finger	257..274	CDD:275368	5/17 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050