DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zif and WIP3

DIOPT Version :9

Sequence 1:	NP_001189188.1	Gene:	Zif / 40795	FlyBaseID:	FBgn0037446	Length:	388	Species:	Drosophila melanogaster
Sequence 2:	NP_172306.1	Gene:	WIP3 / 837349	AraportID:	AT1G08290	Length:	337	Species:	Arabidopsis thaliana

Alignment Length:	252	Identity:	54/252 - (21%)
Similarity:	92/252 - (36%)	Gaps:	74/252 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   144 SDQQECIGDTIEYLEDNYTIEM---------NSDQTEIVLESEKQYEETPSQQLALQEAAKASLK 199
            ||.:|      |..:|..|:::         :.|.::|..:.:|:    |.::..:::......|
plant    89 SDIKE------ENKDDVVTLQIGFPKYHRGSSEDGSDITFDHQKK----PIKREIIEDGVVMMKK 143

  Fly   200 ARRGRVRRGLNSLTTSDGTEKGGYICDVCGNFYEKRGRMMEHRRRHDGICQYACELCDAKFQVRE 264
            .|:.:..   ..:..||        .:|||    ||..:....:.|.|..|:||.:|...|....
plant   144 RRKMKFD---EEIIDSD--------VEVCG----KRFWIPSPAQIHVGPMQFACSICSKTFNRYN 193

  Fly   265 QLRKHMYSHTGSKPYK------------------CSFCS---------------RQFFYESVLKS 296
            .::.||:.| ||:..|                  |..|:               :.|   ..|::
plant   194 NMQMHMWGH-GSEFRKGADSLKGTIQPAAILRLPCYCCAEGCKNNINHPRSKPLKDF---RTLQT 254

  Fly   297 HENVHRGIKPYVCKVCDKAFAYAHSLTKHELIHSDIKLYRCDYCNKDFRLLHHMRQH 353
            |.....|.||:.|..|.||.|.......||  .:..||:.|. |..||:....::.|
plant   255 HYKRKHGSKPFSCGKCGKALAVKGDWRTHE--KNCGKLWYCT-CGSDFKHKRSLKDH 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zif	NP_001189188.1	zf-AD	9..87	CDD:285071
		C2H2 Zn finger	225..245	CDD:275368	5/19 (26%)
		COG5048	<250..369	CDD:227381	33/137 (24%)
		C2H2 Zn finger	253..273	CDD:275368	5/19 (26%)
		zf-H2C2_2	266..288	CDD:290200	8/54 (15%)
		C2H2 Zn finger	281..301	CDD:275368	5/34 (15%)
		zf-H2C2_2	294..318	CDD:290200	9/23 (39%)
		C2H2 Zn finger	309..329	CDD:275368	7/19 (37%)
		C2H2 Zn finger	337..353	CDD:275368	4/15 (27%)
WIP3	NP_172306.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050