DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Zif and si:ch211-89o9.6

DIOPT Version :9

Sequence 1:	NP_001189188.1	Gene:	Zif / 40795	FlyBaseID:	FBgn0037446	Length:	388	Species:	Drosophila melanogaster
Sequence 2:	XP_687655.4	Gene:	si:ch211-89o9.6 / 559243	ZFINID:	ZDB-GENE-030131-7155	Length:	582	Species:	Danio rerio

Alignment Length:	317	Identity:	71/317 - (22%)
Similarity:	118/317 - (37%)	Gaps:	75/317 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 PNEML--IQLLGVSYSNLNDREHIPDGICKSCKVELNMAYQFREKALRKQMEIEEYCRELGLLDE 96
            ||:.|  |::..||.|     |.:..||.||.....|......||.               .::.
Zfish   309 PNKSLTTIKITAVSGS-----EQVHKGIGKSRNSPTNQPSLTAEKT---------------AIET 353

  Fly    97 SDVMMIKEEDGSQQQCDEEMYILEETTTGEEEHQEEKGH----EEYLEVDTSDQQECI---GDTI 154
            :|.::|.:                     ..||:....|    ..:...|::..::|:   .:|:
Zfish   354 ADCLLIDK---------------------PAEHKTSFTHWPTQPSHSYSDSNQDEDCVLVQSETV 397

  Fly   155 EYLEDNYTIEMNSDQTEIVLESEKQY-EETPSQQLALQEAAKASLKARRGR--------VRRGLN 210
            ..:.::.:.:..|..|:....:|:.. ||....|..:.:.::..:....||        ..|...
Zfish   398 TSIRNSKSGQDGSSFTQTHPAAERPLREEERWNQAGIFKQSQTDVSGHIGRPEAIQKDTPNRSSA 462

  Fly   211 SL------TTSDGTEKGGYICDVCGNFYEKRGRMMEHRRRHDGICQYACELCDAKFQVREQLRKH 269
            |.      |.|:.|:.|   ..:.|....||   ||..||...:|:|    |...|.....:..|
Zfish   463 SYFTVIPQTMSNLTQPG---ASLAGPQLPKR---MEKGRRRSYVCKY----CGKAFPGLSNVVAH 517

  Fly   270 MYSHTGSKPYKCSFCSRQFFYESVLKSHENVHRGIKPYVCKVCDKAFAYAHSLTKHE 326
            ...|||.:|::|..|.:.|.....||.|:.||.|.||:.|..|.|.||:..:|..|:
Zfish   518 QRVHTGERPFRCDICGKLFAEAGNLKKHQRVHTGEKPFTCPRCGKQFAWICNLKTHQ 574

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zif	NP_001189188.1	zf-AD	9..87	CDD:285071	15/54 (28%)
		C2H2 Zn finger	225..245	CDD:275368	6/19 (32%)
		COG5048	<250..369	CDD:227381	26/77 (34%)
		C2H2 Zn finger	253..273	CDD:275368	3/19 (16%)
		zf-H2C2_2	266..288	CDD:290200	7/21 (33%)
		C2H2 Zn finger	281..301	CDD:275368	6/19 (32%)
		zf-H2C2_2	294..318	CDD:290200	12/23 (52%)
		C2H2 Zn finger	309..329	CDD:275368	7/18 (39%)
		C2H2 Zn finger	337..353	CDD:275368
si:ch211-89o9.6	XP_687655.4	COG5048	<364..>558	CDD:227381	47/203 (23%)
		zf-C2H2	499..521	CDD:278523	5/25 (20%)
		C2H2 Zn finger	501..521	CDD:275368	5/23 (22%)
		zf-H2C2_2	517..537	CDD:290200	7/19 (37%)
		C2H2 Zn finger	529..549	CDD:275368	6/19 (32%)
		zf-H2C2_2	541..565	CDD:290200	11/23 (48%)
		C2H2 Zn finger	557..574	CDD:275368	6/16 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	129	1.000	Inparanoid score	I4629
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.050