DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zif and CG1792

DIOPT Version :9

Sequence 1:	NP_001189188.1	Gene:	Zif / 40795	FlyBaseID:	FBgn0037446	Length:	388	Species:	Drosophila melanogaster
Sequence 2:	NP_651878.1	Gene:	CG1792 / 43727	FlyBaseID:	FBgn0039860	Length:	372	Species:	Drosophila melanogaster

Alignment Length:	375	Identity:	92/375 - (24%)
Similarity:	153/375 - (40%)	Gaps:	67/375 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 ESPNEMLIQ---------LLGVSYSNLNDREHIPDGICKSCKVELNMAYQFREKALRKQMEIEEY 87
            |.||.:::.         |||      .....:|..||..|:::|..|..|||:.:|.|..::|
  Fly    23 EEPNSVMLHQIEVLTGLFLLG------GPGNELPPFICSPCELDLQTAIAFRERVIRTQKTLQE- 80

  Fly    88 CRELGLLDESDVMMIKEEDGSQQQCDEEMYILEETTTGEEEHQEEKGHEEYLEVDTSDQQECIGD 152
            ...||..:                      ::|....|.|  :|.:..||..|:          :
  Fly    81 SPNLGNAE----------------------LIESFAVGVE--KEIQYAEEVTEI----------E 111

  Fly   153 TIEYLEDNYTIEMNSDQTEIVLESEKQYEETPSQQLALQEAAK------ASLK-ARRGRVRRGLN 210
            .|:.|.:.:.:|...:..||..::|:...:.|:|:..|:.:.|      .|:| |...:..|...
  Fly   112 VIDLLPEEHLLEETEEPYEICEQNEQPQVKVPAQEKKLRRSTKTTPTVFTSVKFADNSQATRTQW 176

  Fly   211 SLTTSDGT-------EKGGYICDVCGNFYEKRGRMMEHRRRHDGICQYACELCDAKFQVREQLRK 268
            |..|.|..       .|...||:.||..:........|..||.|:..:||:.|..:|.....||:
  Fly   177 SRLTEDEVVALKRERRKRDCICEQCGRHFTCPSNFKLHLLRHTGVKSFACDQCSQQFYTATLLRR 241

  Fly   269 HMYSHTGSKPYKCSFCSRQFFYESVLKSHENV-HRGIKPYVCKVCDKAFAYAHSLTKHELIHSDI 332
            |...|.|:..::|.:|...:...|....||.: |..:||:.||.|:|:||.:..|..|.|.|:.:
  Fly   242 HQELHAGNALFQCRYCEATYSNASGRIQHERMRHTNVKPFTCKECNKSFAMSGKLRTHMLSHTGV 306

  Fly   333 KLYRCDYCNKDFRLLHHMRQHEETK--LHQNAVMLAESMKVEMVAEQGGG 380
            :.:.||.|...|....|:..|..:|  .|.::...|....||:..:...|
  Fly   307 RAFHCDSCQVSFVRRSHLTSHYRSKGHAHTSSAQAALDNPVELDVKASNG 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zif	NP_001189188.1	zf-AD	9..87	CDD:285071	17/63 (27%)
		C2H2 Zn finger	225..245	CDD:275368	4/19 (21%)
		COG5048	<250..369	CDD:227381	36/121 (30%)
		C2H2 Zn finger	253..273	CDD:275368	6/19 (32%)
		zf-H2C2_2	266..288	CDD:290200	7/21 (33%)
		C2H2 Zn finger	281..301	CDD:275368	5/20 (25%)
		zf-H2C2_2	294..318	CDD:290200	10/24 (42%)
		C2H2 Zn finger	309..329	CDD:275368	9/19 (47%)
		C2H2 Zn finger	337..353	CDD:275368	5/15 (33%)
CG1792	NP_651878.1	zf-AD	6..80	CDD:214871	17/62 (27%)
		C2H2 Zn finger	198..218	CDD:275368	4/19 (21%)
		C2H2 Zn finger	226..243	CDD:275368	5/16 (31%)
		C2H2 Zn finger	254..275	CDD:275368	5/20 (25%)
		zf-C2H2	281..303	CDD:278523	9/21 (43%)
		C2H2 Zn finger	283..303	CDD:275368	9/19 (47%)
		zf-H2C2_2	296..320	CDD:290200	8/23 (35%)
		C2H2 Zn finger	311..329	CDD:275368	6/17 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	43	1.000	Domainoid score	I19525
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.960