DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zif and Odj

DIOPT Version :9

Sequence 1:	NP_001189188.1	Gene:	Zif / 40795	FlyBaseID:	FBgn0037446	Length:	388	Species:	Drosophila melanogaster
Sequence 2:	NP_650661.1	Gene:	Odj / 42145	FlyBaseID:	FBgn0038551	Length:	430	Species:	Drosophila melanogaster

Alignment Length:	411	Identity:	100/411 - (24%)
Similarity:	163/411 - (39%)	Gaps:	95/411 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 CRVCLAQSERL----------QRLDEIREEGEESPNEMLIQLLGVSYSNLNDREHIPDGICKSCK 64
            ||:|   .||:          :|...||...|:      |..|.:...|:     :|..||..|.
  Fly     5 CRIC---GERIFTPHPKNIFEKRNHRIRMAIEQ------ITGLEIVLENM-----LPQHICACCL 55

  Fly    65 VELNMAYQFREKALRKQMEI-EEYCRELGLLDE---------SDVMMIKEEDGSQQQCDEEMYIL 119
            ::|..|..||::.|.....: :....:.|:..:         ||.::.:|             :|
  Fly    56 LDLTQAVAFRQRCLETHANLHQRISSKAGVASKGSPEVSPVLSDPLLKRE-------------VL 107

  Fly   120 EETTTGEEEHQEEKGHEEYLEVDTSDQQECIGDTIEYLEDNYTIEMNSDQTEIVLESE----KQY 180
            ::|...|::       :|.|:    |.::.:.|..::|||...|.......:|.:|.:    :|.
  Fly   108 DDTVDTEDD-------KELLD----DDKDLMDDDKDFLEDEKPILRYPPAKKIRIEDQNFPNRQS 161

  Fly   181 EETPSQQLALQEAAKASL-------KARRGRVRRGLNSLTTSDGTEKGGYICDVCGNFYEKRGRM 238
            .....::|.:....||..       ..|:.|.||....:..|...    |:||.||..:.....|
  Fly   162 PRVRVKRLRVPVVEKADSPPPPPREHVRKPRKRRPKPKVDRSIKR----YVCDQCGWSFNDHSNM 222

  Fly   239 MEHRRRHDGICQYACELCDAKFQVREQLRKHM-YSHTGSKPYKCSFCSRQFF-------YESVLK 295
            .:|:.||... :::|:.|..||.....||.|: ..|.|.|||.|.||...|.       :|..:.
  Fly   223 KDHKLRHFEE-KFSCDECGRKFYTMPLLRLHIRVHHKGEKPYVCKFCGMGFANSPSRCRHERQMH 286

  Fly   296 SHENVHRGIKPYVCKVCDKAFAYAHSLTKHELIHS----DIKLYRCDYCNKDFRLLHHMRQHEET 356
            ::|.||      .||:|.|.|.......|||..|.    |:.:  |..|||:|:....:.:|..|
  Fly   287 ANELVH------PCKICGKRFNSEKGRLKHEEGHKSDQPDVHI--CLTCNKEFKEAQFLHRHYST 343

  Fly   357 KLHQNAV-MLAESMKVEMVAE 376
            |.|:..| :|....|.|..:|
  Fly   344 KYHRKRVNLLVNGPKEEFQSE 364

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zif	NP_001189188.1	zf-AD	9..87	CDD:285071	21/87 (24%)
		C2H2 Zn finger	225..245	CDD:275368	6/19 (32%)
		COG5048	<250..369	CDD:227381	41/131 (31%)
		C2H2 Zn finger	253..273	CDD:275368	7/20 (35%)
		zf-H2C2_2	266..288	CDD:290200	11/22 (50%)
		C2H2 Zn finger	281..301	CDD:275368	6/26 (23%)
		zf-H2C2_2	294..318	CDD:290200	8/23 (35%)
		C2H2 Zn finger	309..329	CDD:275368	8/19 (42%)
		C2H2 Zn finger	337..353	CDD:275368	5/15 (33%)
Odj	NP_650661.1	zf-AD	5..77	CDD:214871	21/85 (25%)
		COG5048	<202..343	CDD:227381	46/153 (30%)
		C2H2 Zn finger	209..229	CDD:275368	6/19 (32%)
		C2H2 Zn finger	236..256	CDD:275368	7/19 (37%)
		zf-H2C2_2	249..274	CDD:290200	12/24 (50%)
		C2H2 Zn finger	265..283	CDD:275368	4/17 (24%)
		C2H2 Zn finger	298..314	CDD:275368	5/15 (33%)
		zf-C2H2_jaz	322..347	CDD:288983	8/26 (31%)
		C2H2 Zn finger	324..343	CDD:275368	6/18 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG26139
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.060