DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zif and CG17801

DIOPT Version :9

Sequence 1:	NP_001189188.1	Gene:	Zif / 40795	FlyBaseID:	FBgn0037446	Length:	388	Species:	Drosophila melanogaster
Sequence 2:	NP_650660.2	Gene:	CG17801 / 42144	FlyBaseID:	FBgn0038550	Length:	381	Species:	Drosophila melanogaster

Alignment Length:	405	Identity:	96/405 - (23%)
Similarity:	157/405 - (38%)	Gaps:	76/405 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 PQTCRVCLAQSERLQRLDEIREEGEESPN-----EMLIQLLGVSYSNLNDREHIPDGICKSCKVE 66
            |..|.:|.:....|            :|.     |:|.::..::...|...|..|..||.||..:
  Fly     7 PSQCHLCASCFCHL------------NPTIIFCLEVLAKIKDLTGIWLEQNERQPRHICPSCLND 59

  Fly    67 LNMAYQFREKALRKQMEIEEYCRELGLLD--ESDVMMIKEEDGSQQQCDEEMYILEETTTGEEEH 129
            ||.:.:.:::..|...| ....||.||.:  ||.|..|:.|..|.....||.|      ..|...
  Fly    60 LNTSIKLKKRIQRVHNE-ATLRRESGLDEDLESTVSDIEPEGDSSDLESEESY------DSENYP 117

  Fly   130 QEEKGHEEYLEVDTSDQQECIGDTIEYLEDNYTIEMN--SDQTEIVLESEKQYEETPS---QQLA 189
            .::|..|..::::.:.            ||......|  ..:|.::.:.:....||||   :.|.
  Fly   118 FDKKAEESDIDLNLAH------------EDRRNEPHNPYDSETPLIFKHKNPLIETPSFANENLP 170

  Fly   190 LQEAAKASLKARRGRVRRGLNSLTT--------------------------SDGTEKGGYICDVC 228
            .:..||:..|....::...|..|||                          ....:....:|..|
  Fly   171 NKVDAKSPKKGNFIQIGTDLRLLTTYPSIKVVKPLALAPEDVAAENVPPAKRTARKMQSLVCPKC 235

  Fly   229 GNFYEKRGRMMEHRRRHDGICQYACELCDAKFQVREQLRKH-MYSHTGSKPYKCSFCSRQFFYES 292
            |..::....:..|..||.|...:.|..||.:|..:...|.| ...|.|.:|::|:|||..||..:
  Fly   236 GRVFKTPYNLKTHMVRHTGEKNFPCTFCDKRFVTKYLARLHERVRHMGEQPFECNFCSATFFTST 300

  Fly   293 VLKSHENVH--RGIKPYVCKVCDKAFAYAHSLTKHELIHSDIKLYRCDYCNKDFRLLHHMRQHEE 355
            ...|||.:.  |.:: |.|..|.|.|.....|.||:.:||.:|.:.|..|..:|.....:|.|.:
  Fly   301 AKSSHERIRHIRDLR-YQCDQCTKRFNTKTCLNKHKFLHSGLKPFDCVICQINFARKATLRSHFD 364

  Fly   356 TKLHQ---NAVMLAE 367
            :..||   :|::.:|
  Fly   365 SVAHQKRASAILESE 379

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zif	NP_001189188.1	zf-AD	9..87	CDD:285071	17/82 (21%)
		C2H2 Zn finger	225..245	CDD:275368	4/19 (21%)
		COG5048	<250..369	CDD:227381	39/124 (31%)
		C2H2 Zn finger	253..273	CDD:275368	6/20 (30%)
		zf-H2C2_2	266..288	CDD:290200	9/22 (41%)
		C2H2 Zn finger	281..301	CDD:275368	9/19 (47%)
		zf-H2C2_2	294..318	CDD:290200	9/25 (36%)
		C2H2 Zn finger	309..329	CDD:275368	7/19 (37%)
		C2H2 Zn finger	337..353	CDD:275368	4/15 (27%)
CG17801	NP_650660.2	zf-AD	9..74	CDD:285071	16/76 (21%)
		zf-C2H2	231..252	CDD:278523	4/20 (20%)
		C2H2 Zn finger	232..252	CDD:275368	4/19 (21%)
		zf-H2C2_2	244..269	CDD:290200	8/24 (33%)
		C2H2 Zn finger	260..281	CDD:275368	6/20 (30%)
		C2H2 Zn finger	289..308	CDD:275368	9/18 (50%)
		C2H2 Zn finger	318..338	CDD:275368	7/19 (37%)
		C2H2 Zn finger	346..362	CDD:275368	4/15 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439346
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.890