DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Zif and CG6654

DIOPT Version :9

Sequence 1:	NP_001189188.1	Gene:	Zif / 40795	FlyBaseID:	FBgn0037446	Length:	388	Species:	Drosophila melanogaster
Sequence 2:	NP_650429.1	Gene:	CG6654 / 41831	FlyBaseID:	FBgn0038301	Length:	639	Species:	Drosophila melanogaster

Alignment Length:	149	Identity:	48/149 - (32%)
Similarity:	74/149 - (49%)	Gaps:	7/149 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   218 TEKGGYICDVCGNFYEKRGRMMEHRRRHDGICQYACELCDAKFQVREQLRKHMYSHTGSKPYKCS 282
            :|...:.|::|.:.:..:..:..|.|.|.|...:.||:|.|:|.....|.||...|||.:||.|.
  Fly   463 SETKSFKCELCPHSFVTKAELTSHARTHTGDKPFECEVCLARFTTSCSLAKHKRKHTGERPYACD 527

  Fly   283 FCSRQFFYESVLKSHENVHRGIKPYVCKVCDKAFAYAHSLTKHELIHSDIKLYRCDYCNKDFRLL 347
            .|..:|...:|||:|...|.|.:||||..|.|.|........|:..|...::|.|..||::|:.:
  Fly   528 LCPMRFTALNVLKNHRRTHTGERPYVCPFCSKTFTQRGDCQMHQRTHQGERIYICPVCNEEFKSM 592

  Fly   348 HHMR-------QHEETKLH 359
            ..||       ||::..:|
  Fly   593 PEMRSHLAGHEQHDKRLVH 611

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zif	NP_001189188.1	zf-AD	9..87	CDD:285071
		C2H2 Zn finger	225..245	CDD:275368	4/19 (21%)
		COG5048	<250..369	CDD:227381	41/117 (35%)
		C2H2 Zn finger	253..273	CDD:275368	8/19 (42%)
		zf-H2C2_2	266..288	CDD:290200	10/21 (48%)
		C2H2 Zn finger	281..301	CDD:275368	7/19 (37%)
		zf-H2C2_2	294..318	CDD:290200	12/23 (52%)
		C2H2 Zn finger	309..329	CDD:275368	5/19 (26%)
		C2H2 Zn finger	337..353	CDD:275368	6/22 (27%)
CG6654	NP_650429.1	zf-AD	6..79	CDD:285071
		C2H2 Zn finger	331..354	CDD:275368
		COG5048	<357..570	CDD:227381	36/106 (34%)
		C2H2 Zn finger	360..380	CDD:275368
		C2H2 Zn finger	385..406	CDD:275370
		C2H2 Zn finger	414..434	CDD:275368
		zf-H2C2_2	427..451	CDD:290200
		C2H2 Zn finger	442..490	CDD:275368	5/26 (19%)
		C2H2 Zn finger	470..487	CDD:275368	2/16 (13%)
		zf-H2C2_2	482..507	CDD:290200	9/24 (38%)
		C2H2 Zn finger	498..518	CDD:275368	8/19 (42%)
		zf-H2C2_2	510..534	CDD:290200	10/23 (43%)
		C2H2 Zn finger	526..546	CDD:275368	7/19 (37%)
		zf-H2C2_2	539..563	CDD:290200	12/23 (52%)
		C2H2 Zn finger	554..574	CDD:275368	5/19 (26%)
		C2H2 Zn finger	582..602	CDD:275368	6/19 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	84	1.000	Inparanoid score	I1804
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.960