DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zif and ranshi

DIOPT Version :9

Sequence 1:	NP_001189188.1	Gene:	Zif / 40795	FlyBaseID:	FBgn0037446	Length:	388	Species:	Drosophila melanogaster
Sequence 2:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster

Alignment Length:	378	Identity:	104/378 - (27%)
Similarity:	170/378 - (44%)	Gaps:	55/378 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 QTCRVCLAQSERLQRLDEIREEGEESPNEMLIQLLGVSYSNLNDREHIPDGICKSCKVELNMAYQ 72
            :.||.| .:....:|...|.|:..::..|.:..|.|....|.:.   :|:.:|.||:..|..|..
  Fly     4 KVCRTC-GKRTNAERSLNIFEKRNQTTLEHIKLLTGAVLKNCST---LPNRLCASCQTCLQQAIS 64

  Fly    73 FREKALRKQMEIEEYCRELGLLDESDVMMIKEEDGSQQQCDEEMYILEETTTGEEEHQEEKGHEE 137
            |||:.|..|.|:      |...|:.|.:.|.:|....        :||         |||
  Fly    65 FRERCLEVQREL------LHSQDDEDFLRICQESPKS--------VLE---------QEE----- 101

  Fly   138 YLEVDTSDQQECIGDTIEYLED--NYTIEMNSDQTEIVLESEKQYEETPSQQ---------LALQ 191
             ||:|.::    |...:|.|:|  ...|:.:..:.|.:|...|..|:.|:.:         ..:.
  Fly   102 -LELDLAE----ISIEVERLDDLNEGPIQSSGFKVEDILNESKINEDEPNNEDDIDYSEMDYLIY 161

  Fly   192 EA-----AKASLKARRGRVRRGLNSLTTSDGTEKGGYICDVCGNFYEKRGRMMEHRRRHDGICQY 251
            |:     ||..||:.....::..|.....|....  :.|:.|||..:.|...:.|.:||.|:.::
  Fly   162 ESDTEVDAKQELKSDSENPKKRRNRRNPRDSNRT--FFCEECGNHIKDRISFILHCKRHRGVKEF 224

  Fly   252 ACELCDAKFQVREQLRKHMYSHTGSKPYKCSFCSRQFFYESVLKSHENVHRGIKPYVCKVCDKAF 316
            .||.|:.:|....:|::|:..|||.||:||..|||.|...|....||..|...:|:|||.|:.||
  Fly   225 GCEFCEDRFCTPAELKRHIRKHTGEKPFKCRHCSRSFSDYSTRLKHERTHTNERPFVCKECNNAF 289

  Fly   317 AYAHSLTKHELIHSDIKLYRCDYCNKDFRLLHHMRQHEETKLHQNAVMLAESM 369
            ..::.|..|.|:|:..|.:|||.|:|.|....|:..|..:..|:..:..|:::
  Fly   290 TTSYILKNHMLVHTGEKAFRCDLCDKLFSRYTHLTTHYRSNAHRRNMQKADTI 342

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zif	NP_001189188.1	zf-AD	9..87	CDD:285071	22/77 (29%)
		C2H2 Zn finger	225..245	CDD:275368	6/19 (32%)
		COG5048	<250..369	CDD:227381	43/118 (36%)
		C2H2 Zn finger	253..273	CDD:275368	6/19 (32%)
		zf-H2C2_2	266..288	CDD:290200	12/21 (57%)
		C2H2 Zn finger	281..301	CDD:275368	8/19 (42%)
		zf-H2C2_2	294..318	CDD:290200	10/23 (43%)
		C2H2 Zn finger	309..329	CDD:275368	8/19 (42%)
		C2H2 Zn finger	337..353	CDD:275368	6/15 (40%)
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871	22/81 (27%)
		C2H2 Zn finger	198..218	CDD:275368	6/19 (32%)
		COG5048	222..>276	CDD:227381	21/53 (40%)
		C2H2 Zn finger	226..246	CDD:275368	6/19 (32%)
		zf-H2C2_2	238..262	CDD:290200	12/23 (52%)
		C2H2 Zn finger	254..274	CDD:275368	8/19 (42%)
		zf-H2C2_2	269..291	CDD:290200	10/21 (48%)
		C2H2 Zn finger	282..302	CDD:275368	8/19 (42%)
		zf-H2C2_2	295..319	CDD:290200	11/23 (48%)
		C2H2 Zn finger	310..328	CDD:275368	7/17 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	60	1.000	Domainoid score	I10558
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.960