DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zif and CG14667

DIOPT Version :9

Sequence 1:	NP_001189188.1	Gene:	Zif / 40795	FlyBaseID:	FBgn0037446	Length:	388	Species:	Drosophila melanogaster
Sequence 2:	NP_001014607.1	Gene:	CG14667 / 40643	FlyBaseID:	FBgn0037317	Length:	337	Species:	Drosophila melanogaster

Alignment Length:	377	Identity:	86/377 - (22%)
Similarity:	151/377 - (40%)	Gaps:	68/377 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 CRVCLAQSERLQRLDEIREEGEESPNEMLIQLLG--------VSYSNLNDREHIPDGICKSCKVE 66
            ||:|   :.::.        |.:....:.|.:.|        ::...|...:.:|:.:|:.|..|
  Fly     7 CRIC---ANKIM--------GHQRDRNIFIHMRGKYLGQLKLITGVELTRNQGLPEIVCERCFSE 60

  Fly    67 LNMAYQFREKALRKQMEIEEYCRELGLLDESDVMMIKEEDGSQQQCDEEMYILEETTTGEEEHQE 131
            |::|.:|||:.:..|..:.:..::..  |:|.|.:    :.|.:..||::...::.    |.|.:
  Fly    61 LDLATKFRERCIFSQKYLLDIIKKTS--DQSTVHV----ELSSEPLDEQLIDADQL----ETHYD 115

  Fly   132 EKGHEEYLEVDTSDQQECIGDTIEYLEDNYTIEMNSDQTEIVLESEKQYEETPSQQLALQEAAKA 196
            :            ||..|...|.|..:|...||::.|.:..|:.:.:...|. :||..|||....
  Fly   116 D------------DQYVCYQGTKEEHQDLEEIELDDDPSAAVIAAAEAAAEA-AQQEDLQEQEME 167

  Fly   197 SLKARRGRVRRGLNSLTTSDGTEKGGYICDVCGNFYEKRGRMME----HRRRHDGICQYACELCD 257
            ....||...                 :|||.||..:.......|    |:.|.|....:.|..|.
  Fly   168 RAAKRRSNF-----------------FICDECGTLFHDAFLYTEHLNGHQNRRDMNQFFPCPECP 215

  Fly   258 AKFQVREQLRKHMYS-HTGSKPYKCSFCSRQFFYESVLKSHENVHRGIKPYVCKVCDKAFAYAHS 321
            ..|..:..|::|... |..::.::|:.|...|........|:..|:..:||.|..|...|:....
  Fly   216 QTFNKKALLKQHRTQVHLINRRFQCTICHEAFASLGAKLRHDKAHKNERPYPCLECGMIFSSVSE 280

  Fly   322 LTKHELIHS-DIKLYRCDYCNKDFRLLHHMRQHEETKLHQNAVMLAESMKVE 372
            |..|...|| .|:.:||:.||.||.....:..|.:|..|:.   ||:.|:.|
  Fly   281 LQNHFSTHSKQIRKFRCEPCNMDFITRRGLVAHTKTAPHKR---LAKYMQDE 329

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zif	NP_001189188.1	zf-AD	9..87	CDD:285071	17/84 (20%)
		C2H2 Zn finger	225..245	CDD:275368	6/23 (26%)
		COG5048	<250..369	CDD:227381	32/120 (27%)
		C2H2 Zn finger	253..273	CDD:275368	5/20 (25%)
		zf-H2C2_2	266..288	CDD:290200	5/22 (23%)
		C2H2 Zn finger	281..301	CDD:275368	4/19 (21%)
		zf-H2C2_2	294..318	CDD:290200	7/23 (30%)
		C2H2 Zn finger	309..329	CDD:275368	5/19 (26%)
		C2H2 Zn finger	337..353	CDD:275368	5/15 (33%)
CG14667	NP_001014607.1	zf-AD	6..80	CDD:214871	17/83 (20%)
		C2H2 Zn finger	179..199	CDD:275368	5/19 (26%)
		C2H2 Zn finger	211..232	CDD:275368	5/20 (25%)
		C2H2 Zn finger	240..260	CDD:275368	4/19 (21%)
		zf-C2H2_8	243..313	CDD:292531	20/69 (29%)
		C2H2 Zn finger	268..288	CDD:275368	5/19 (26%)
		C2H2 Zn finger	297..316	CDD:275368	6/18 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG26139
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.970