DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Zif and CG17359

DIOPT Version :9

Sequence 1:NP_001189188.1 Gene:Zif / 40795 FlyBaseID:FBgn0037446 Length:388 Species:Drosophila melanogaster
Sequence 2:NP_648679.1 Gene:CG17359 / 39549 FlyBaseID:FBgn0036396 Length:339 Species:Drosophila melanogaster


Alignment Length:393 Identity:89/393 - (22%)
Similarity:146/393 - (37%) Gaps:106/393 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly     8 QTCRVCLAQSERLQRLDEIREEGEESPNE----------MLIQLLGVSYSNLNDREHIPDGICKS 62
            |.||||..:|:.|  || |..|...|.|.          ||.:..|.|   ::..:.:|..||..
  Fly     5 QMCRVCRDESDCL--LD-IYTEPYASSNRVQEQEPVLATMLRECSGCS---VHKEDGMPQFICVE 63

  Fly    63 CKVELNMAYQFRE------------KALRKQMEIEEYCRELGLLDESDVMMIKEEDGSQQQCDEE 115
            |...:..||:.|.            :.:.|:::..|||..:|...|..:.:...|.|...:..|.
  Fly    64 CAEAVRNAYRLRRQCRKSHQYFEQLRLMMKELDDIEYCLNIGDNIEPQMPVSVMEAGKTPETSEP 128

  Fly   116 MYILEETTTGEEEHQEEKGHEEYLEVDTSDQQECIGDTIEY-LEDNYT---IEMNSDQTEIVLES 176
            :.:             |....:|:..:.......:.|..|: |..:|:   ...|..:     ..
  Fly   129 LLV-------------ELVQVKYMPPEPKPISSPLPDNNEHKLAQSYSPAKTPHNKSK-----RR 175

  Fly   177 EKQYEE----TPSQQLALQEAAKASLKARRGRVRRGLNSLTTSDGTEKGGYICDVCGNFYEKRGR 237
            .:.|.:    :|..:|..::..|....::||:.:|                   |.|        
  Fly   176 ARSYSDNDSWSPDSELEHEDDDKIWNASKRGKPKR-------------------VPG-------- 213

  Fly   238 MMEHRRRHDGICQYACELCDAKFQVREQLRKHMYSHTGSKPYKCSFCSRQFFYESVLKSHENVHR 302
                        .|.|:||...|..::.|..||..|||.:|||||.|.|.|..:..|:||...|.
  Fly   214 ------------PYRCKLCTQSFTQKQNLEIHMRIHTGERPYKCSLCPRSFAQKGNLQSHTRCHT 266

  Fly   303 GIKPYVCKVCDKAFAYAHSLTKHELIHSDIKLYRCDYCNKDFRLLHHMRQH-------------E 354
            |.:|:.|..|.|.|.....|..|...|:..:.::|..|.:.|:.|:.:::|             :
  Fly   267 GERPFGCPNCPKRFRQVGQLQVHTRTHTGEQPFKCSKCQQSFKQLNGLQKHMSAHTRGKRRTSSQ 331

  Fly   355 ETK 357
            |||
  Fly   332 ETK 334

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ZifNP_001189188.1 zf-AD 9..87 CDD:285071 24/99 (24%)
C2H2 Zn finger 225..245 CDD:275368 2/19 (11%)
COG5048 <250..369 CDD:227381 40/121 (33%)
C2H2 Zn finger 253..273 CDD:275368 7/19 (37%)
zf-H2C2_2 266..288 CDD:290200 13/21 (62%)
C2H2 Zn finger 281..301 CDD:275368 8/19 (42%)
zf-H2C2_2 294..318 CDD:290200 10/23 (43%)
C2H2 Zn finger 309..329 CDD:275368 6/19 (32%)
C2H2 Zn finger 337..353 CDD:275368 4/15 (27%)
CG17359NP_648679.1 zf-AD 6..88 CDD:285071 23/87 (26%)
zf-C2H2 215..237 CDD:278523 8/21 (38%)
C2H2 Zn finger 217..237 CDD:275368 7/19 (37%)
zf-H2C2_2 229..254 CDD:290200 14/24 (58%)
C2H2 Zn finger 245..265 CDD:275368 8/19 (42%)
zf-H2C2_2 257..282 CDD:290200 10/24 (42%)
C2H2 Zn finger 273..293 CDD:275368 6/19 (32%)
zf-H2C2_2 286..310 CDD:290200 6/23 (26%)
C2H2 Zn finger 301..321 CDD:275368 5/19 (26%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45457840
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.930

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