DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Zif and CG10321

DIOPT Version :9

Sequence 1:NP_001189188.1 Gene:Zif / 40795 FlyBaseID:FBgn0037446 Length:388 Species:Drosophila melanogaster
Sequence 2:NP_001261124.1 Gene:CG10321 / 37464 FlyBaseID:FBgn0034643 Length:855 Species:Drosophila melanogaster


Alignment Length:419 Identity:86/419 - (20%)
Similarity:155/419 - (36%) Gaps:95/419 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    14 LAQSE-----------RLQRLDEIREEGEESPNEMLIQLLGVSYSNLNDREHI--PDGICKSCKV 65
            |.|||           :.|.:|||.:|.|:...|.......:....|.|.|.:  |||       
  Fly   390 LTQSESQDHEYFDDLDQQQAMDEIEDEEEQMKPEEDQDTFIIEEIQLEDDEMLDDPDG------- 447

  Fly    66 ELNMAYQFREKALRKQMEIEEYCRELG----------LLDESDVMMIKEEDGSQQQCDEEMYILE 120
                            .||::.|..:|          :.|:.:..:::..|| :...|.:...::
  Fly   448 ----------------EEIDQDCEYIGEEQDPHLSGDVDDDLEYSIMEPPDG-ETSVDIDQAFMD 495

  Fly   121 ETTTGEEEHQE-------EKGHEEYLEVDT------------------------SDQQECIGDTI 154
            ...:..::|||       |....|:.:..|                        |:.|...|.|:
  Fly   496 SEQSHHQQHQEEMQSISLENAVVEFSQATTTTEALVGPTMTVSSASPTPKRAKRSNHQIPAGVTL 560

  Fly   155 EYLEDNYTIEMNSDQTEIVLESEKQYEETPSQQLALQEAAKASLKARRGRVRRGLNSLTTSDGTE 219
            |..:.......::..:::...:.:|..:|.|  :.....|..:.:.....|...:...|:..|: 
  Fly   561 EPCDHQPPAAGSTTSSKLAAANSRQLVQTAS--VIAAAGADDNYEIDANLVTEFIRQHTSPLGS- 622

  Fly   220 KGGYICDVCGNFYEKRGRMMEHRRRHD----GIC--QYACELCDAKFQVREQLRKHMYSHTG-SK 277
             |.|||.:|...:.:...:..|...|.    ..|  |..|::|...|:....||.||.:|.. |.
  Fly   623 -GRYICHLCSTEFRQFKGLQNHMHSHTNWIRANCKKQPQCQICLKSFKGPGMLRMHMKTHDAESS 686

  Fly   278 PYKCSFCSRQFFYESVLKSHENVHRGIKPYVCKV--CDKAFAYAHSLTKH-ELIHSDI--KLYRC 337
            ...|:.|:|.|..:::|..|...|:. :.|.|.|  |.|.|:.|.:|..| |..|.::  .|::|
  Fly   687 TPMCTICNRTFKSKAILYRHRQTHQQ-RAYCCGVANCRKNFSSAVNLKWHVERKHPEVVDPLFKC 750

  Fly   338 DYCNKDFRLLHHMRQHEETKLHQNAVMLA 366
            ..|...:..:..::.|.|:..|...|.::
  Fly   751 GECGSLYDNVDSLQLHVESTDHSAEVQIS 779

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ZifNP_001189188.1 zf-AD 9..87 CDD:285071 19/85 (22%)
C2H2 Zn finger 225..245 CDD:275368 3/19 (16%)
COG5048 <250..369 CDD:227381 35/123 (28%)
C2H2 Zn finger 253..273 CDD:275368 7/19 (37%)
zf-H2C2_2 266..288 CDD:290200 9/22 (41%)
C2H2 Zn finger 281..301 CDD:275368 6/19 (32%)
zf-H2C2_2 294..318 CDD:290200 9/25 (36%)
C2H2 Zn finger 309..329 CDD:275368 9/22 (41%)
C2H2 Zn finger 337..353 CDD:275368 2/15 (13%)
CG10321NP_001261124.1 zf-AD 12..80 CDD:214871
ASF1_hist_chap <405..516 CDD:304562 25/134 (19%)
C2H2 Zn finger 627..647 CDD:275368 3/19 (16%)
C2H2 Zn finger 661..681 CDD:275368 7/19 (37%)
C2H2 Zn finger 690..710 CDD:275368 6/19 (32%)
C2H2 Zn finger 717..740 CDD:275368 9/22 (41%)
C2H2 Zn finger 750..767 CDD:275368 2/16 (13%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
00.000

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