DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zif and M03D4.4

DIOPT Version :9

Sequence 1:	NP_001189188.1	Gene:	Zif / 40795	FlyBaseID:	FBgn0037446	Length:	388	Species:	Drosophila melanogaster
Sequence 2:	NP_001023313.1	Gene:	M03D4.4 / 177375	WormBaseID:	WBGene00019751	Length:	505	Species:	Caenorhabditis elegans

Alignment Length:	253	Identity:	67/253 - (26%)
Similarity:	112/253 - (44%)	Gaps:	51/253 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   110 QQCDEEMYILEETTTGEEEHQEEKGHEEYLEVDTSDQQECIGDTIEYLEDNYTIEMNSDQ---TE 171
            :.|....:.|:|.    :.|:.|: ||   .|:..||:|      :.:||      :||:   .:
Worm     8 RDCSGAFHSLDEL----QRHEREE-HE---TVEQGDQEE------DRMED------DSDELAMIK 52

  Fly   172 IVLESEKQYEETPSQQLALQEAAKASLKARRGRVRRGLNSLTTSDGT---EKGGYICDVCGNFYE 233
            |.:|......:|.|.||:                   :|..|.|:.:   |||.|.|:.|...:.
Worm    53 IKIEDSDFLSDTDSSQLS-------------------MNPTTPSEKSSSGEKGRYECEDCHEMFA 98

  Fly   234 KRGRMMEHRRRHDGICQYACELCDAKFQVREQLRKHMYSHTGSKPYKCSFCSRQFFYESVLKSHE 298
            .:..:..|.|.|.|...::|..|..:|..|:.|:||...|||.:.:.|..|::.||.:..|..|.
Worm    99 VKRELATHMRIHSGEQPHSCTQCGKEFGTRQLLKKHWMWHTGERSHVCPHCNKAFFQKGHLTQHL 163

  Fly   299 NVHRGIKPYVCKVCDKAFAYAHSLTKHELIHSDIKLYRCDYCNKDFR---LL--HHMR 351
            .:|.|.:|:.|..|.|.|.:...|.:|..||.: :.:.|..|.:.|.   :|  ||::
Worm   164 MIHSGGRPHECPQCHKTFIFKFDLNRHMKIHQE-RGFSCQQCGRSFLKQVMLDEHHLK 220

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zif	NP_001189188.1	zf-AD	9..87	CDD:285071
		C2H2 Zn finger	225..245	CDD:275368	4/19 (21%)
		COG5048	<250..369	CDD:227381	33/107 (31%)
		C2H2 Zn finger	253..273	CDD:275368	7/19 (37%)
		zf-H2C2_2	266..288	CDD:290200	8/21 (38%)
		C2H2 Zn finger	281..301	CDD:275368	6/19 (32%)
		zf-H2C2_2	294..318	CDD:290200	9/23 (39%)
		C2H2 Zn finger	309..329	CDD:275368	6/19 (32%)
		C2H2 Zn finger	337..353	CDD:275368	6/20 (30%)
M03D4.4	NP_001023313.1	C2H2 Zn finger	90..110	CDD:275368	4/19 (21%)
		zf-H2C2_2	102..127	CDD:290200	7/24 (29%)
		C2H2 Zn finger	118..138	CDD:275368	7/19 (37%)
		C2H2 Zn finger	146..166	CDD:275368	6/19 (32%)
		zf-H2C2_2	158..181	CDD:290200	8/22 (36%)
		zf-C2H2	172..194	CDD:278523	6/21 (29%)
		C2H2 Zn finger	174..194	CDD:275368	6/19 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000