DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG9727 and Rfx4

DIOPT Version :9

Sequence 1:NP_001262317.1 Gene:CG9727 / 40794 FlyBaseID:FBgn0037445 Length:1329 Species:Drosophila melanogaster
Sequence 2:XP_006514176.1 Gene:Rfx4 / 71137 MGIID:1918387 Length:745 Species:Mus musculus


Alignment Length:681 Identity:131/681 - (19%)
Similarity:222/681 - (32%) Gaps:226/681 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly   310 TINWVRSHLEHDAQVSIPKQDVYNDYIAYCERLSIKPLSTADFGKVMKQVFPGVRPRRLGTRGNS 374
            |:.|:..:.|....|.||:..:|..|:.:||:...:|::.|.|||:::|.||.:..|||||||.|
Mouse    71 TLQWLEENYEIAEGVCIPRSALYMHYLDFCEKNDTQPVNAASFGKIIRQQFPQLTTRRLGTRGQS 135

  Fly   375 RYCY--------------------------AAMRKTTKLT------------------------P 389
            :|.|                          ...|:.||.|                        |
Mouse   136 KYHYYGIAVKESSQYYDVMYSKKGAAWVSETGKREVTKQTVAYSPRSKLGTLLPDFPNVKDLNLP 200

  Fly   390 PQLPQ------------LCKTEQIVAGDSNSDPSQLTSASSLGGLP----STGGDSECWDVV--- 435
            ..||:            .|:........:|.|..|........|:|    ...|.|...::|   
Mouse   201 ASLPEEKVSTFIMMYRTHCQRILDTVIRANFDEVQSFLLHFWQGMPPHMLPVLGSSTVVNIVGVC 265

  Fly   436 -----RSWAEKLLNTKLESVADLSSRIKSNNATVSTKKYTPREPKEKRV-LADIG--------PL 486
                 ::.:..|:.|.|:::.|        :.|...:|:..:..:..:| |.|:.        .|
Mouse   266 DSILYKAISGVLMPTVLQALPD--------SLTQVIRKFAKQLDEWLKVALHDLPENLRNIKFEL 322

  Fly   487 KKRRKKKRKGSTSSESSCN------------------------QLVTGQDAGSSQEASDEQ---I 524
            .:|..:..:..||....|.                        ..:|.|...:.:::.||.   |
Mouse   323 SRRFSQILRRQTSLNHLCQASRTVIHSADITFQMLEDWRNVDLSSITKQTLYTMEDSRDEHRRLI 387

  Fly   525 LKIKQEIIDSPIHPQQPPIGYLQQVTPM------NLATDQRSSSAVRNLTPKILEMGS---PAVV 580
            :::.|| .|..:..|.|...|::.:..|      .:|..::.|  ::.:..:.|.|.|   ..|:
Mouse   388 IQLYQE-FDHLLEEQSPIESYIEWLDTMVDRCVVKVAAKRQGS--LKKVAQQFLLMWSCFGTRVI 449

  Fly   581 --LTQQEVSPTG------IVIKDEVEDYTSNIFCK----KVLKAQQTKGFWANSPSSGTTSGVGL 633
              :|.......|      ::..|.|.....::.|:    ::::|.:.:|..|.:...        
Mouse   450 RDMTLHSAPSFGSFHLIHLMFDDYVLYLLESLHCQERANELMRAMKGEGSTAEAQEE-------- 506

  Fly   634 LVPPTITTTSATPPPPNSETSPVPGPGLSMGPPSQMMSTSSVSPSSTVDTTPK-----VASRNQM 693
                 |..|.||||.|:      |||..|   |::..::..|.|.|:..:.|.     :::...|
Mouse   507 -----IILTEATPPTPS------PGPSFS---PAKSATSVEVPPPSSPVSNPSPEYTGLSTAGAM 557

  Fly   694 MILRAKRLMAAENAALAAAEDS-GLP--ENLGLPRERVISICNMDKHELDDYFLPGEDEENSEEP 755
            .............||.:.||:| .||  .:..:|...|       .|.:..|      ....|..
Mouse   558 QSYTWSLTYTVTTAAGSPAENSQQLPCMRSTHMPSSSV-------THRIPVY------SHREEHG 609

  Fly   756 DNELLQYFQMGDAEEKQLNSLDAAEQNKNP--------------------------------QEP 788
            ......|...|:.....|       ||:.|                                .||
Mouse   610 YTGSYNYGSYGNQHPHPL-------QNQYPALPHDTAISGPLHYSPYHRSSAQYPFNSPTSRMEP 667

  Fly   789 PTMGSAPEAMPAP--GRGAAVVAAAAAMLAP 817
            ..|.|.|...|.|  .|...|..|.|...:|
Mouse   668 CLMSSTPRLHPTPVTPRWPEVPTANACYTSP 698

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG9727NP_001262317.1 RFX_DNA_binding 307..383 CDD:280427 28/98 (29%)
Rfx4XP_006514176.1 RFX_DNA_binding 69..144 CDD:367002 28/72 (39%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3712
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D346630at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.910

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