Protein Alignment CG9727 and RFX4

DIOPT Version :9

• Sequence 1: NP_001262317.1
• Gene: CG9727 / 40794
• FlyBaseID: FBgn0037445
• Length: 1329
• Species: Drosophila melanogaster
• Sequence 2: NP_001193620.1
• Gene: RFX4 / 5992
• HGNCID: 9985
• Length: 744
• Species: Homo sapiens
• Alignment Length: 890
• Identity: 167/890 - (18%)
• Similarity: 262/890 - (29%)
• Gaps: 397/890 - (44%)

  Fly   310 TINWVRSHLEHDAQVSIPKQDVYNDYIAYCERLSIKPLSTADFGKVMKQVFPGVRPRRLGTRGNS 374
            |:.|:..:.|....|.||:..:|..|:.:||:...:|::.|.|||:::|.||.:..|||||||.|
Human    70 TLQWLEENYEIAEGVCIPRSALYMHYLDFCEKNDTQPVNAASFGKIIRQQFPQLTTRRLGTRGQS 134

  Fly   375 RYCYAAMRKTTKLTPPQLPQLCKTEQIVAGDSNSDPSQLTSASSLGGLPSTGGDSECWDVVRSWA 439
            :|.|..                    |...:|                      |:.:||:.|
Human   135 KYHYYG--------------------IAVKES----------------------SQYYDVMYS-- 155

  Fly   440 EKLLNTKLESVADLSSRIKSNNATVSTKKYTPREPKEKRVLADIGPLKKRRKKKRKGSTSSESSC 504
                                                 |:..|.:....|:...|:..:.|..|..
Human   156 -------------------------------------KKGAAWVSETGKKEVSKQTVAYSPRSKL 183

  Fly   505 NQLVTGQDAGSSQEASDEQILKIKQEIIDSPIHPQQPPIGYLQQVTPMNLATDQRSSSAV--RNL 567
            ..|:                             |:.|.:..|.  .|.:|..::.|:..:  |..
Human   184 GTLL-----------------------------PEFPNVKDLN--LPASLPEEKVSTFIMMYRTH 217

  Fly   568 TPKILEMGSPAVVLTQQEVSPTGIVIK---DEVEDYTSNIFCKKVLKAQQTKGFWANSP------ 623
            ..:||:                 .||:   |||:.:..:              ||...|
Human   218 CQRILD-----------------TVIRANFDEVQSFLLH--------------FWQGMPPHMLPV 251

  Fly   624 -SSGTTSGV-------------GLLVPPTITTTSATPPPPNSETSPVPGPGLSMGPPSQMMSTSS 674
             .|.|...:             |:|:|   |...|.|.
Human   252 LGSSTVVNIVGVCDSILYKAISGVLMP---TVLQALPD--------------------------- 286

  Fly   675 VSPSSTVDTTPKVASRNQMMILRAKRLMAAENAALAAAEDSGLPENLG-------------LPRE 726
                          |..|::...||:|......||     ..|||||.             |.|:
Human   287 --------------SLTQVIRKFAKQLDEWLKVAL-----HDLPENLRNIKFELSRRFSQILRRQ 332

  Fly   727 RVIS-ICNMDK---HELDDYFLPGED-----------------EENSEEPDNELLQYFQMGD--- 767
            ..:: :|...:   |..|..|...||                 |::.:|....:.|.:|..|
Human   333 TSLNHLCQASRTVIHSADITFQMLEDWRNVDLNSITKQTLYTMEDSRDEHRKLITQLYQEFDHLL 397

  Fly   768 ------------------------AEEKQLNSLDAAEQ--------------NKNPQEPPTMGS- 793
                                    |.::|.:....|:|              :......|:.||
Human   398 EEQSPIESYIEWLDTMVDRCVVKVAAKRQGSLKKVAQQFLLMWSCFGTRVIRDMTLHSAPSFGSF 462

  Fly   794 -----------------------APEAMPA-PGRGAA------VVAAAAAMLAPVPAPSMLPAQA 828
                                   |.|.|.| .|.|:.      ::...||...|.|.||..||::
Human   463 HLIHLMFDDYVLYLLESLHCQERANELMRAMKGEGSTAEVREEIILTEAAAPTPSPVPSFSPAKS 527

  Fly   829 G-----------VGSASASLALMSKKHQQQNQHQNL----------QLQRSKQLPLISNNKRKIS 872
            .           |.:.|.....:|.....|:...:|          ..:.|:|||.:.|.
Human   528 ATSVEVPPPSSPVSNPSPEYTGLSTTGAMQSYTWSLTYTVTTAAGSPAENSQQLPCMRNT----- 587

  Fly   873 LSNASSNGSNKNCIFLPISPN--TNGSVTTPTATGSSNPSQNCFASPGLTRMKQRPNLLSKQQSL 935
             ...||:.:::    :|:.|:  .:|      .|||.|     :.|.|    .|.|:.:..|...
Human   588 -HVPSSSVTHR----IPVYPHREEHG------YTGSYN-----YGSYG----NQHPHPMQSQYPA 632

  Fly   936 ---DCDNRDPMIGA--HRKGRGYVYSYPTS-----TSASAP---PSPSILPQWMCRNWSLGGGNI 987
               |.....|:..|  ||....|.::.|||     ..:|.|   |:| :.|:|.    .:...|.
Human   633 LPHDTAISGPLHYAPYHRSSAQYPFNSPTSRMEPCLMSSTPRLHPTP-VTPRWP----EVPSANT 692

  Fly   988 SSFADSSHSADPLVNQNSMDLETSLALTGENELDTSEMQRSQSVP 1032
            ...:.|.|||.   ..||.|:.|.|. |..|    ||.:..|..|
Human   693 CYTSPSVHSAR---YGNSSDMYTPLT-TRRN----SEYEHMQHFP 729

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9727	NP_001262317.1	RFX_DNA_binding	307..383	CDD:280427	28/72 (39%)
RFX4	NP_001193620.1	RFX_DNA_binding	68..141	CDD:308073	28/90 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3712
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D346630at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910