Protein Alignment CG9727 and RFX3

DIOPT Version :9

• Sequence 1: NP_001262317.1
• Gene: CG9727 / 40794
• FlyBaseID: FBgn0037445
• Length: 1329
• Species: Drosophila melanogaster
• Sequence 2: XP_024303398.1
• Gene: RFX3 / 5991
• HGNCID: 9984
• Length: 800
• Species: Homo sapiens
• Alignment Length: 851
• Identity: 147/851 - (17%)
• Similarity: 247/851 - (29%)
• Gaps: 391/851 - (45%)

  Fly    13 TKSAAPAATTAPVSNSIPIPQPIPVALPLQKPNANPYGNCSLQPADIVY---SATRFQGPAIHAK 74
            |..|:.||....|...:|:.|.:.....:|:..       .:.||.:.|   |.|.:...||...
Human    48 TSVASQAAVPTQVVQQVPVQQQVQQVQTVQQVQ-------HVYPAQVQYVEGSDTVYTNGAIRTT 105

  Fly    75 GSPLTITPV--GPVGG-----APASAQISPTSHTHVPVPVATPSGFVPPPFSNATSASGGVSTSV 132
            ..|.|.|.:  ...||     ..:|||::....:|..|                  .:||:
Human   106 TYPYTETQMYSQNTGGNYFDTQGSSAQVTTVVSSHSMV------------------GTGGI---- 148

  Fly   133 LTPNPFATASANAAGLAFANAFSFSTAQQLGL--GKIMHAMGGATAGVPSAPVPVTTTPATAAPS 195
                                        |:|:  |:::.:.||...
Human   149 ----------------------------QMGVTGGQLISSSGGTYL------------------- 166

  Fly   196 TPTIAGPRHPNEGVPAASGVINSTIAENVMNALSNSNSAGSVPSEEKMRRVLQVIETSLDDNAKL 260
                                        :.|::.||..:.:..:......:...|||
Human   167 ----------------------------IGNSMENSGHSVTHTTRASPATIEMAIET-------- 195

  Fly   261 QISQILERVSGLKPIEKLFLYLRLPGECADTDPLRQPQNPLGTRSEINHTINWVRSHLEHDAQVS 325
                 |::..||.....                           |.:|..:.|:..:.|....||
Human   196 -----LQKSDGLSTHRS---------------------------SLLNSHLQWLLDNYETAEGVS 228

  Fly   326 IPKQDVYNDYIAYCERLSIKPLSTADFGKVMKQVFPGVRPRRLGTRGNSRYCYAAMRKTTKLTPP 390
            :|:..:||.|:.:|:...:.|::.|.|||:::.:|.|:|.|||||||||:|.|..:|     ..|
Human   229 LPRSTLYNHYLRHCQEHKLDPVNAASFGKLIRSIFMGLRTRRLGTRGNSKYHYYGIR-----VKP 288

  Fly   391 QLPQLCKTEQIVAGDSNSDPSQLTSASSLGGLPSTGGDSECWDVVRSWAEKLLNTKLESVADLSS 455
            ..|                                                 ||...|.:..::.
Human   289 DSP-------------------------------------------------LNRLQEDMQYMAM 304

  Fly   456 RIKSNNATVSTKKYTPREPKEKRVLADIGPLKKRRKKKRK------GSTSSESSCNQLVTGQDAG 514
            |               ::|.::         |:|.|..:|      |.|.|         ||..|
Human   305 R---------------QQPMQQ---------KQRYKPMQKVDGVADGFTGS---------GQQTG 336

  Fly   515 SSQEASDEQILKIKQEIIDSPIHPQQPPIGYLQQVTPMNLATDQRSSSAVRNLTPKILEMGSPAV 579
            :|          ::|.:|....|.||    :|               .|.|.|.    |.|
Human   337 TS----------VEQTVIAQSQHHQQ----FL---------------DASRALP----EFG---- 364

  Fly   580 VLTQQEVS--PTGIVIKD-------------EVEDYTSNIFCKKVLKAQQTKGFWANSPSS---G 626
               :.|:|  |.|...:|             .:.|...|:....:.|..||  ||..|||:   |
Human   365 ---EVEISSLPDGTTFEDIKSLQSLYREHCEAILDVVVNLQFSLIEKLWQT--FWRYSPSTPTDG 424

  Fly   627 TT-----------------------------------------SGVGLLVPPTITTTSATPPPPN 650
            ||                                         :.|.:|:|..:.      |.|:
Human   425 TTITESSNLSEIESRLPKAKLITLCKHESILKWMCNCDHGMYQALVEILIPDVLR------PIPS 483

  Fly   651 SETSPVPGPGLSM---------GPPSQMMSTSSVSPSSTVDTTPKVASRNQMMILRAKRLMAAEN 706
            :.|..:.....|:         ..|.:|:.|...:.|:...|..:..|.|.:          |:.
Human   484 ALTQAIRNFAKSLEGWLSNAMNNIPQRMIQTKVAAVSAFAQTLRRYTSLNHL----------AQA 538

  Fly   707 AALAAAEDSGLPENLG-LPR-------ERVISICNMDKHELD----DYFLPGEDEENSEE----P 755
            |.......|.:.:.|. |.|       |:...:|..|.:.:.    |:.:..:.:...|:    .
Human   539 ARAVLQNTSQINQMLSDLNRVDFANVQEQASWVCQCDDNMVQRLETDFKMTLQQQSTLEQWAAWL 603

  Fly   756 DNELLQ 761
            ||.::|
Human   604 DNVMMQ 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9727	NP_001262317.1	RFX_DNA_binding	307..383	CDD:280427	29/75 (39%)
RFX3	XP_024303398.1	RFX1_trans_act	<81..167	CDD:309643	24/182 (13%)
		RFX_DNA_binding	214..286	CDD:308073	29/76 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3712
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D346630at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.910