Protein Alignment CG9727 and RFX1

DIOPT Version :9

• Sequence 1: NP_001262317.1
• Gene: CG9727 / 40794
• FlyBaseID: FBgn0037445
• Length: 1329
• Species: Drosophila melanogaster
• Sequence 2: XP_011526467.1
• Gene: RFX1 / 5989
• HGNCID: 9982
• Length: 1089
• Species: Homo sapiens
• Alignment Length: 586
• Identity: 126/586 - (21%)
• Similarity: 204/586 - (34%)
• Gaps: 192/586 - (32%)

  Fly     7 QLGAQWTKSAAPAATTAP-------VSNSIPIPQPIPV--ALPLQKPNANPYGNCS---LQPADI 59
            |..:..:|:|.....|.|       |..|:|:.|...|  |.| |.|...|....:   |||..:
Human   212 QANSSSSKTAGAPTGTVPQQLQVHGVQQSVPVTQERSVVQATP-QAPKPGPVQPLTVQGLQPVHV 275

  Fly    60 VYSATRFQGPAIHA-KGSPLTITPVGPVGGAPASAQISPTSHTHVPVPVATPSGFVPPPFSNATS 123
            ...::..|.||..| :..|....|..|....||.:..:|...:..|          |||.....:
Human   276 AQESSGSQFPARKAEQRDPRPTPPPEPPPRPPACSGEAPQLGSPEP----------PPPHYEPGA 330

  Fly   124 ASGGVSTSVLTPN-----------PFATASANAAG------------LAFANAFSFSTAQQLGLG 165
            ........||.|:           |.:...|.|:.            |.|..|.:....|||...
Human   331 EQWVELVGVLPPHLLLPQQKVVFEPLSRLPARASPDQRVRIQRIPQVLVFGTAATALKVQQLQQV 395

  Fly   166 KIMH-------------------AMGGATAGVPSAPVPVTTTPATA---APSTPTIAGPRHPNEG 208
            .:.|                   |:..:|...|..|: .|.|.:|:   |..|.|.......::.
Human   396 PVPHVYSSQVQYVEGGDASYTASAIRSSTYSYPETPL-YTQTASTSYYEAAGTATQVSTPATSQA 459

  Fly   209 VPAASGVI------NSTIAENVMNALSNSNS--------------------AGSVPSEEKMRRVL 247
            | |:||.:      :..:|.:.......|||                    :||...
Human   460 V-ASSGSMPMYVSGSQVVASSTSTGAGASNSSGGGGSGGGGGGGGGGGGGGSGSTGG-------- 515

  Fly   248 QVIETSLDDNAKLQISQILERVSGLKPIEKLFLYLRLPGECADTDPLRQPQNPLGTRSE-INH-- 309
                                                 .|..|.|..: |....||:.|: .:|
Human   516 -------------------------------------GGSGAGTYVI-QGGYMLGSASQSYSHTT 542

  Fly   310 -----TINWVRSHLEHDAQVSIPKQDVYNDYIAYCERLSIKPLSTADFGKVMKQVFPGVRPRRLG 369
                 |:.|:..:.|....||:|:..:|..|:.:|:...::|::.|.|||:::.||.|:|.||||
Human   543 RASPATVQWLLDNYETAEGVSLPRSTLYCHYLLHCQEQKLEPVNAASFGKLIRSVFMGLRTRRLG 607

  Fly   370 TRGNSRYCYAAMRKTTKLTPPQLPQLCKTEQIVA--GDSNSDPSQL---------TSASSLGGLP 423
            |||||:|.|..:|  .|.:.|.| :|.:.:|.:|  |...|...:|         |:..::|..|
Human   608 TRGNSKYHYYGLR--IKASSPLL-RLMEDQQHMAMRGQPFSQKQRLKPIQKMEGMTNGVAVGQQP 669

  Fly   424 STGGDSECWDVVRSWAEKLLNTKLESVADLSSRIKSN----NATVSTKKYTPREPKEKRVLADIG 484
            |||                       ::|:|::::..    :|:.|...:|..:.:.|.:...:|
Human   670 STG-----------------------LSDISAQVQQYQQFLDASRSLPDFTELDLQGKVLPEGVG 711

  Fly   485 P 485
            |
Human   712 P 712

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9727	NP_001262317.1	RFX_DNA_binding	307..383	CDD:280427	30/82 (37%)
RFX1	XP_011526467.1	TFIIA	75..>280	CDD:281188	18/68 (26%)
		RFX1_trans_act	224..481	CDD:282451	57/269 (21%)
		RFX_DNA_binding	545..621	CDD:280427	30/77 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3712
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D346630at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910