Protein Alignment CG9727 and rfx6

DIOPT Version :10

• Sequence 1: NP_001262317.1
• Gene: CG9727 / 40794
• FlyBaseID: FBgn0037445
• Length: 1329
• Species: Drosophila melanogaster
• Sequence 2: NP_001410707.1
• Gene: rfx6 / 556925
• ZFINID: ZDB-GENE-041014-299
• Length: 930
• Species: Danio rerio
• Alignment Length: 1087
• Identity: 210/1087 - (19%)
• Similarity: 342/1087 - (31%)
• Gaps: 380/1087 - (34%)

  Fly   224 VMNALSNSNSAGSVPSEEKMRRVLQVIETSLD---------DNAKLQISQILERVSGLKPIEKLF 279
            |::......|..|:.|||.:..        ||         ...|..||||::
Zfish     3 VIHLAEADESNASISSEEDLGH--------LDYSKPFAAKQTQPKKSISQIIK------------ 47

  Fly   280 LYLRLPGECADTDPLRQPQNPLGTRSEINHTINWVRSHLEHDAQVSIPKQDVYNDYIAYCERLSI 344
                        |..:|.|          .|:.|:..:......|.:|:..:|..|:.:|.:..:
Zfish    48 ------------DKKKQTQ----------LTLQWLEDNYIVCEGVCLPRCILYAHYLDFCRKEKL 90

  Fly   345 KPLSTADFGKVMKQVFPGVRPRRLGTRGNSRYCYAAMRKTTKLTPPQLPQLCKTEQIVAGDSNSD 409
            .|...|.|||.::|.||.:..|||||||:|:|.|..:                      |...|.
Zfish    91 DPACAATFGKTIRQKFPLLTTRRLGTRGHSKYHYYGI----------------------GIKESS 133

  Fly   410 PSQLTSASSLGGLPSTGGDSECWDVVRSWAEKLLNTKLESVADLSSRIKSNNATVSTKKYT---- 470
             :...|..|..||....|                           |::|:...  .|:||:
Zfish   134 -AYYHSVYSGKGLTRFSG---------------------------SKLKNEGG--FTRKYSLSSK 168

  Fly   471 -----PREPKEKR-VLADIGPLKKRRKKKRKGSTSSESSCN------------QLVTGQDAGSSQ 517
                 |..|..:. ||.|              |.|.|..|:            .|:|
Zfish   169 TGTLLPEFPSAQHLVLQD--------------SVSKEKVCSFPVKNTVYMKCIDLLT-------- 211

  Fly   518 EASDEQILKIKQEIIDSPIHPQQPPIGYLQQVTPMNLATDQRSSSAVRNLTPKILE--MGSPAVV 580
              ||..:|.|.|  :|:.|         :...|......|...:.....:...:|.  .|.|..:
Zfish   212 --SDSVLLLICQ--VDTLI---------MMYKTHCQCILDNAINVNFEEIQNFLLHFWQGMPEHL 263

  Fly   581 LTQQEVSPTGIVIKDEVEDYTSNIFC------KKVLKAQQTKGFWANSPSSGTTSGVGLLVPPTI 639
            |...| :|   ||.|        |||      .|||                    ..:|:|.|:
Zfish   264 LPLLE-NP---VIVD--------IFCVCDSILYKVL--------------------TDVLIPATM 296

  Fly   640 TTTSATPPPPNSETSPVPGPGLSMGPPSQMMSTSSVSPS------STVDTTPKVASRNQMMILRA 698
            ...                      |.|.:....:.:..      |:::..|::.|..::.|  |
Zfish   297 QDM----------------------PESLLADIRNFAKHWEHWMLSSLENLPEILSEKKVPI--A 337

  Fly   699 KRLMAAENAALAAAEDSGLPENLGLPRERVISICN-MDKHELDDY----FLPGEDEENSE---EP 755
            :|.:::.....:....:.:.......:..|.|:.| :||.:|:..    .|...::::|:   |.
Zfish   338 RRFVSSLKRQTSFLHLAQIARPALFDQIVVTSMVNDIDKVDLNSIGSQALLSVTNDQDSDFYSEY 402

  Fly   756 DN-----ELLQYFQMGDAEEKQLNSLDAAEQNKNPQEPPTMGSAPEAMPAPGRGAAVVAAAAAML 815
            |:     ||....:.....|..:..||:..:.|            ...|:...|.:|...|...|
Zfish   403 DSISVFQELKDLLRKNATVESFIEWLDSVVEQK------------VIKPSKQNGRSVKKRAQDFL 455

  Fly   816 -------APVPAPSMLPAQAGVGSASASLALMSKK-----HQQQNQHQNLQLQRSKQLPLISNNK 868
                   |.|.....|......||......|:.:.     ..|.|..:...||.     |:....
Zfish   456 LKWSFFGARVMHNLTLNNATSFGSFHLIRMLLDEYILLAIETQFNNDKEQDLQN-----LLEKYM 515

  Fly   869 RKISLSNASSNGSNKNCIFLPISPNTNGSVTTPTATGSSNPSQNCFASPGLTRMKQRPNLLSKQQ 933
            |....|.|:...|..:| || .:.|..|..::.:|.....|.::.:.:           |.:.||
Zfish   516 RSADASKATFTASPSSC-FL-ANRNKPGVSSSDSAVKDEIPPEDDYLT-----------LAAAQQ 567

  Fly   934 SLDCDNRDPMIGAHRKGRGYVYSYPTSTSASAPPSPSILPQWMCRNWSLGGGNISSFADSSHSAD 998
            .|              |.|.|..:      ||.|.          |:::.|.     .|.|.::.
Zfish   568 GL--------------GAGTVVYH------SADPD----------NFTIAGQ-----MDFSQNSA 597

  Fly   999 PL---------------VNQNSMDL--ETSLALTGENELDTSEMQRSQSVPLSQLQRRGSQQSPS 1046
            ||               :||..|.:  :||..:.|:....|......||     |....|...|:
Zfish   598 PLMTPPISPAMMNRSSVINQGPMAMRPQTSCPIQGQLPCQTFPEPLYQS-----LHNPPSGSYPN 657

  Fly  1047 LNFYSENSNSQQSAPLKETGLLYEEVEVDSLLSANFTRKFNSITQQT-ATTCSSS----AGSSSG 1106
            .::|.         |:..|....|        |..:....:.:::.. :.:|::|    .|||.|
Zfish   658 ASYYQ---------PMFRTQTHTE--------SGRYAFSGHHLSKDCFSNSCTASPYGTRGSSGG 705

  Fly  1107 YSSGGSAGIVSRSVPSTPLPHQQQNSLTSLNGGGGAASS-GGGVMGIGNGGNCGVGNGFFT---- 1166
            |::.|.||:.:.:|      ...::|.....|..|||.. .|.|...|:.|..|..:|:..
Zfish   706 YTAAGDAGMETEAV------QMLESSGFGFGGTTGAADGCSGPVCSSGHSGYYGSSSGYVDAPRM 764

  Fly  1167 ---ISDSFNWEGSTSN-NSQLGYAHSYSARNSLDISKSMPTTPIATQ 1209
               |....:...|.|: .|...||.::...|.|| ..|..|.|..|:
Zfish   765 GTFIDQHVSVISSVSSIRSVSAYAEAHDPLNILD-DTSRKTRPYYTE 810

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9727	NP_001262317.1	PHA03247	<40..207	CDD:223021
		RFX_DNA_binding	307..385	CDD:460512	25/77 (32%)
rfx6	NP_001410707.1	RFX_DNA_binding	56..131	CDD:460512	26/96 (27%)