Protein Alignment CG9727 and Rfx6

DIOPT Version :10

• Sequence 1: NP_001262317.1
• Gene: CG9727 / 40794
• FlyBaseID: FBgn0037445
• Length: 1329
• Species: Drosophila melanogaster
• Sequence 2: NP_001152861.1
• Gene: Rfx6 / 320995
• MGIID: 2445208
• Length: 927
• Species: Mus musculus
• Alignment Length: 1056
• Identity: 185/1056 - (17%)
• Similarity: 314/1056 - (29%)
• Gaps: 377/1056 - (35%)

  Fly   198 TIAGPRHPNE--GVPAASGVINSTIAENVMNALSNSNSAGSVPSEEKMRRVLQVIETSLDDNAKL 260
            |.||.|...|  |.|.....:.|.:..|..|..|....|.:..|:.|.              |..
Mouse    51 TAAGARSSGEKGGDPGLQVGVKSEMQLNNGNFSSEEEDADTQESKTKA--------------ADP 101

  Fly   261 QISQILERVSGLKPIEKLFLYLRLPGECADTDPLRQPQNPLGTRSEINHTINWVRSHLEHDAQVS 325
            |:||       .|.|.::.           .|..:|.|          .|:.|:..:......|.
Mouse   102 QLSQ-------KKSITQMM-----------KDKKKQTQ----------LTLQWLEDNYIVCEGVC 138

  Fly   326 IPKQDVYNDYIAYCERLSIKPLSTADFGKVMKQVFPGVRPRRLGTRGNSRY-------------- 376
            :|:..:|..|:.:|.:..::|...|.|||.::|.||.:..|||||||:|:|
Mouse   139 LPRCILYAHYLDFCRKEKLEPACAATFGKTIRQKFPLLTTRRLGTRGHSKYHYYGIGIKESSAYY 203

  Fly   377 -------------------------CYAAMRKTTKLTPPQLP-------QLC----KTEQIV--- 402
                                     .|:...||..|. |:.|       |.|    |.:.::
Mouse   204 HSVYSGKGLTRFSGSKLKNEGGFTRKYSLSSKTGTLL-PEFPSAQHLVYQGCISKDKVDTLIMMY 267

  Fly   403 ----------AGDSNSDPSQLTSASSLGGLPSTGGDS-----------ECWDVVRSWAEKLLNTK 446
                      |.:.|.:..|........|:|    |.           :.:.|..|...|:|...
Mouse   268 KTHCQCILDNAINGNFEEIQHFLLHFWQGMP----DHLLPLLENPVIIDIFCVCDSILYKVLTDV 328

  Fly   447 L---------ES-VADLSSRIKS-NNATVSTKKYTPREPKEKRVLADIGPLKKRRKKKRKGSTS- 499
            |         || :||:.:..|: ....||:.:..|....:|::     |:.:|.....|..||
Mouse   329 LIPATMQEMPESLLADIRNFAKNWEQWVVSSLENLPEALIDKKI-----PILRRFVSSLKRQTSF 388

  Fly   500 ------------SESSCNQLVTGQDAGSSQEASDEQILKIKQEI-IDSPIHPQQPPIGYLQQVTP 551
                        .:...|.:|:..:.........:.:|.|.... .:|.|:.:...|...|::..
Mouse   389 LHLAQIARPALFDQHVVNAMVSDIEKVDLNSIGSQALLTISNSTDTESDIYSEHDSITVFQELKD 453

  Fly   552 --------------MNLATDQR--------------------------SSSAVRNLTPK------ 570
                          ::...:||                          .:..:.|||..
Mouse   454 LLKKNATVEAFIEWLDTVVEQRVIKMSKQNGRSLKKRAQDFLLKWSFFGARVMHNLTLNNASSFG 518

  Fly   571 ---ILEMGSPAVVLTQQEVSPTGIVIKDEVEDYTSNIFCKKVLKAQQTKGFWANSPSS---GTTS 629
               ::.|.....:|...|..     ..::.|....|:..|.:..:..:|..:..||||   ...:
Mouse   519 SFHLIRMLLDEYILLAMETQ-----FNNDKEQELQNLLDKYMKNSDASKAAFTASPSSCFLANRN 578

  Fly   630 GVGLLVPPTITTTSATPPPPNSETSPVPGPGLSMG--PPSQMMSTSSVSPSSTVDTTPKVASRNQ 692
            ....|...|:...|      :.|||.||.|....|  ||       ::.|.||.||
Mouse   579 KASSLASDTVKNES------HVETSYVPLPSSQPGAIPP-------ALHPFSTEDT--------- 621

  Fly   693 MMILRAKRLMAAENAALAAAEDSGLPENLGLPRERVISICNMDKHELDDYFLPGEDEENSEEPDN 757
                                      :|:.||.:  |.:.....|.:.....|......|
Mouse   622 --------------------------DNMPLPGQ--IELSQSTGHLMTPPISPAIASRGS----- 653

  Fly   758 ELLQYFQMGDAEEKQLNSLDAAEQNKNPQEPPTMGSAPEAMPAPGRGAAVVAAAAAMLAPVPAPS 822
                                ...|......||::|:   .:.||       ...:....|: .|:
Mouse   654 --------------------VINQGPMASRPPSVGT---VLSAP-------THCSTYAEPI-YPT 687

  Fly   823 MLPAQAGVGSASASLALMSKKHQQQNQHQNLQLQRSKQLPLISNNKRKIS--LSNASSNGSNKNC 885
            :.||.......:::...|.:  .|.:...:|...|::....::..::::|  ....|..||..||
Mouse   688 LSPANHDFYGTNSNYQTMFR--TQSHPASSLYAHRAEHGRCMAWTEQQLSRDFFGGSCAGSPYNC 750

  Fly   886 IFLPISPNTNGSVTTPTATGSSNPSQNCFASPGLTRMKQRPNLLSKQQSLDCDNRDPMIGAHRKG 950
                         ..|::.|.|..:|...:...|.....  |.||...:..|..
Mouse   751 -------------RPPSSYGPSTHTQESHSMQVLNTGSF--NFLSNAGAGSCQG----------- 789

  Fly   951 RGYVYSYPTSTSASAPPSPSILPQWMCRNWSLGGGNISSFADSSHSADPLVNQNSMDLETSLALT 1015
                     ||..|..|:            ...|.||:  ...:|....:|||:...:.:..:|.
Mouse   790 ---------STLPSNSPN------------GYYGNNIN--YSEAHRLGSMVNQHVSVISSVRSLP 831

  Fly  1016 GENELDTSEMQRSQSVPLSQLQRRGSQQSPSLNFYSEN------------SNSQQSAPLKETGLL 1068
            ..:::..         ||:.|.....:|:.|  ||::.            ||.|...|...:..:
Mouse   832 PYSDIHD---------PLNILDDSSRKQNNS--FYADTLSPVACRTTVVASNLQTQIPSSSSQCM 885

  Fly  1069 Y---EEVEVDSLLSAN 1081
            |   .:..|...|.:|
Mouse   886 YGTSNQYPVQDSLDSN 901

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9727	NP_001262317.1	PHA03247	<40..207	CDD:223021	4/8 (50%)
		RFX_DNA_binding	307..385	CDD:460512	26/116 (22%)
Rfx6	NP_001152861.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	81..108		9/47 (19%)
		RFX_DNA_binding	123..198	CDD:460512	24/74 (32%)