Protein Alignment Dmtn and tmcc3

DIOPT Version :10

• Sequence 1: NP_001163531.1
• Gene: Dmtn / 40792
• FlyBaseID: FBgn0037443
• Length: 679
• Species: Drosophila melanogaster
• Sequence 2: NP_001072261.1
• Gene: tmcc3 / 779714
• XenbaseID: XB-GENE-977501
• Length: 473
• Species: Xenopus tropicalis
• Alignment Length: 426
• Identity: 170/426 - (39%)
• Similarity: 248/426 - (58%)
• Gaps: 50/426 - (11%)

  Fly   254 DRLNTKIQCTKESIRQEQTARDDNVNEYLKLAASADKQQLQRIKAVFEKKNQKSAHNISQLQKKL 318
            |.|..||....|.|:.||||||.||.|||||..||||||..|||.|||||||||||:|:||||||
 Frog    69 DSLKQKILKVTEQIKIEQTARDGNVAEYLKLVNSADKQQAGRIKQVFEKKNQKSAHSIAQLQKKL 133

  Fly   319 DNYTKRAKDLQNHQFQTKSQHRQPREV---LRDVGQGLR--NVGGNIRDGITGFSGS----VMSK 374
            :.|.|:.|:::.:...:||.....:::   |:||..|.|  ..|...:.|:.|.|.:    |.:|
 Frog   134 EQYHKKLKEIEQNGSASKSSKDISKDLQHSLKDVTNGSRPAGQGETSKMGVPGVSLTPPMFVFNK 198

  Fly   375 PREFAHLIKNKFGSADNINQMSEAELQGMQSANADVLGSERLQQVPGAGTSTGSGGGGQNNNTGG 439
            .||||:||:|||||||||..:.                            :|......:.|:...
 Frog   199 SREFANLIRNKFGSADNIAHLK----------------------------NTLDDFHPETNSRNL 235

  Fly   440 AGSGT----GKFNSDNGSECSSVTSESIPGGSGKS----QSGASQYHIVLKTLLTELAERKAENE 496
            :||.|    .|:.||:  ||||.||.|......::    ::.||..|..|...|.||.|.|....
 Frog   236 SGSATIVTKPKYASDD--ECSSGTSASADSNGNQTFDTGRTNASDSHGNLSVFLEELREIKDAQS 298

  Fly   497 KLKERIERLETG-QKEFNNLTATLESERYRAEGLEEQINDLTELHQNEIENLKQTIADMEEKVQY 560
            :|.|.||.|:.. :::::.::.||:.||||.|.||:|:||||:|||:|..||||.:|.:||||.|
 Frog   299 QLAEDIETLKVHFKRDYSLISQTLQEERYRYERLEDQLNDLTDLHQHETTNLKQDLASIEEKVAY 363

  Fly   561 QSDERLRDVNEVLENCQTRISKMEHMSQQQYVTVEGIDNSNARALVVKLINVVLTILQVVLLLVA 625
            |:.||.||:.|.||:||||:||:| :.||:.:.::. :..||:.|:.|.||::|.::.|:|:.|:
 Frog   364 QAYERSRDIQEALESCQTRVSKLE-LHQQEQLAIQS-ETVNAKVLLGKCINILLALITVILVCVS 426

  Fly   626 TAAGIIMPFLKTRVRVLTTFLSICFVIFVIRQWPDV 661
            |.|..:.|.:|:|:.::.||.::..:..|.:.|..:
 Frog   427 TIAKFVAPMMKSRLHIIFTFFAVTLLAVVCKNWDHI 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dmtn	NP_001163531.1	Tmemb_cc2	249..658	CDD:463036	169/421 (40%)
tmcc3	NP_001072261.1	Tmemb_cc2	64..459	CDD:463036	169/421 (40%)