DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dmtn and Tex28

DIOPT Version :9

Sequence 1:	NP_001163531.1	Gene:	Dmtn / 40792	FlyBaseID:	FBgn0037443	Length:	679	Species:	Drosophila melanogaster
Sequence 2:	NP_001178032.1	Gene:	Tex28 / 690282	RGDID:	1582832	Length:	409	Species:	Rattus norvegicus

Alignment Length:	465	Identity:	105/465 - (22%)
Similarity:	198/465 - (42%)	Gaps:	115/465 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   219 SGNEDYYSSFVSDEFDSSKKVHRRCHERSSSVQAIDRLNTKIQCTKESIRQEQTARDDNVNEYLK 283
            |.:||..||..|   .|..::.|...|         .:..:|....|.:|.|:.:||:|...|||
  Rat    27 SSHEDCPSSHTS---FSDGELARNVRE---------GVKHRIFYLSEQLRVEKASRDENTMSYLK 79

  Fly   284 LAASADKQQLQRIKAVFEKKNQKSAHNISQLQKKLDNYTKRAKDLQNHQFQTKSQHRQPREVLRD 348
            |.:.||:.|...|:..||:.||:::..|:.:::||....::.|:|:        :...|..::.:
  Rat    80 LISKADRHQAPHIRKAFERVNQRTSATIAHIERKLYQCHQQLKELE--------EGCSPTSLVLN 136

  Fly   349 VGQGL---RNVGGNIRDGITGFSGSVMSKPREFAHLIKNKFGSADNINQMS--EAELQGMQSANA 408
            |..|:   :..||.|       ..|.:|||       ..:.....|:.:.|  |:.|.|||..
  Rat   137 VDSGMDSHKQPGGKI-------LYSKLSKP-------DGEDSLPINVARSSTLESHLPGMQQR-- 185

  Fly   409 DVLGSERLQQVPGAGTSTGSGGGGQNNNTGGAGSGTGKFNSDNGSECSSVTSESIPGGSGKSQSG 473
                                                 ||:.                    .:..
  Rat   186 -------------------------------------KFSD--------------------KKYV 193

  Fly   474 ASQYHIVLKTLLTELAERKAENEKLKERIERL-ETGQKEFNNLTATLESERYRAEGLEEQINDLT 537
            |.|..::|:.:..||.|.|..:..|:...:.| |:...:...:..:|:.::.|...:||.:||..
  Rat   194 AQQQKLLLQKMKEELTEAKKVHASLQLSHQNLKESHMIDVRRILESLQEKKTRQSLMEEHVNDHL 258

  Fly   538 ELHQNEIENLKQTIADMEEKVQYQSDERLRDVNEVLENCQTRISKMEHMSQQQYVTVEGIDNSNA 602
            :.:.:||.:|||.:|..|||:.|.|.||.:::.:|:|..:.||:|:|.:.|...:.:.....:..
  Rat   259 QRYLDEICHLKQHLACTEEKMAYLSYERAKEIWDVMETFKNRITKLETLQQATQLEMMASLRTRP 323

  Fly   603 RALVVKLINVVLTILQVVLLLVATAAGIIMPFLKTRVRVLTTFLSICFVIFVIRQWPDVQDIGSG 667
            :....:.|:::||:..::|::|:|.....:|.|.:|:|:        |::|:|        ||.|
  Rat   324 KDFFFRFISLLLTLTTILLVVVSTLCSCPLPLLNSRLRI--------FIVFMI--------IGLG 372

  Fly   668 LVRHLKQSLV 677
            .:...|:.::
  Rat   373 TLAWQKRHVI 382

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dmtn	NP_001163531.1	Tmemb_cc2	253..658	CDD:287269	92/410 (22%)
Tex28	NP_001178032.1	Tmemb_cc2	50..377	CDD:402057	96/432 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166334418
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR17613
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.940