Protein Alignment Dmtn and tmcc1b

DIOPT Version :10

• Sequence 1: NP_001163531.1
• Gene: Dmtn / 40792
• FlyBaseID: FBgn0037443
• Length: 679
• Species: Drosophila melanogaster
• Sequence 2: NP_001073477.1
• Gene: tmcc1b / 563581
• ZFINID: ZDB-GENE-061013-154
• Length: 656
• Species: Danio rerio
• Alignment Length: 693
• Identity: 237/693 - (34%)
• Similarity: 338/693 - (48%)
• Gaps: 115/693 - (16%)

  Fly    27 RGSSSNLRASRSPSASRSTEQMSRERASE----AAAATQTAAATAG-----------------GA 70
            :|.|....|....|..|:..::|| ||||    .:..|..|....|                 ..
Zfish     3 QGGSEQPGAEEPDSGGRAEREVSR-RASEPDHGLSKITHNALENMGALGHGLKHFFQPQRRRSSV 66

  Fly    71 TAHSAGGTAGGSAAATTTAG---GATSGSGTASANTNSNSSASSSTVAAAQAAV-----YSGGNT 127
            :.|....::.|........|   |...|. |.:.|::.::||..:.::.....:     ...|.:
Zfish    67 SPHDYTSSSTGPILEPPEVGPELGEAQGI-TVAPNSDPHTSAPPAALSRVLQQIRGPPMMKRGTS 130

  Fly   128 VTGSLGSAGVVARGFRSHSPTHRRRSRE-------RQRRTHGSDQGG------LLAYSGLVGV-- 177
            :......||.|....:..||...|||.:       |.|.:..:|...      :|..||....
Zfish   131 LQSRRSKAGGVGEAPQKGSPQIHRRSTQDPLLQAGRPRSSSTTDTPSSPALVDMLLTSGYHSTEE 195

  Fly   178 ---NDMTDFLGPQQGGGGGGGGGGGGGGGGGSA-GTGSGLEDSRLSGNEDYYSSFVSDEFDSSKK 238
               .|..:..||............||..|..|. ||   |:..|
Zfish   196 ADRQDRLEVSGPAVSPNALSTCSDGGQYGVDSVDGT---LDPQR--------------------- 236

  Fly   239 VHRRCHERSSSVQAIDRLNTKIQCTKESIRQEQTARDDNVNEYLKLAASADKQQLQRIKAVFEKK 303
                      :.|||.:|..||....|.|:.|||||||||.||||||.:|||||..|||.|||||
Zfish   237 ----------TKQAIAQLQQKILKLTEQIKIEQTARDDNVAEYLKLANNADKQQSTRIKQVFEKK 291

  Fly   304 NQKSAHNISQLQKKLDNYTKRAKDLQNHQFQTKSQHRQPREVLRDVGQGLRNVGGNIRDGITGFS 368
            |||||..|.|||:||::|.::.::::::...     |||::||||:.|||::||..:..|::..|
Zfish   292 NQKSAQTIQQLQRKLEHYHRKLREVEHNGIP-----RQPKDVLRDMHQGLKDVGAKVTGGLSSIS 351

  Fly   369 -------GSVMSKPREFAHLIKNKFGSADNINQMSEA--ELQGMQSANADVLGSERLQQVPGAGT 424
                   |:|:|||||||.||:||.||.:||..:.::  |.||....::..:...|   .||.|.
Zfish   352 QATHSAAGAVVSKPREFASLIRNKLGSTENIPALKDSLDEQQGDDPVSSTGVAGTR---TPGPGQ 413

  Fly   425 STGSGGGGQNNNTGGAGSGTGKFNSDNGSECSSVTSESIPGGSGKSQSGASQY--HIVLKTLLTE 487
            ...|...|..::...|.||:...||..|:          |||...|:....::  .....|||.|
Zfish   414 LQSSPKYGSEDDCSSATSGSAGANSTTGA----------PGGPPSSKGNTLEHGQGSGFDTLLHE 468

  Fly   488 LAERKAENEKLKERIERLETG-QKEFNNLTATLESERYRAEGLEEQINDLTELHQNEIENLKQTI 551
            :.|.|....:|:|..:.|::. |:::.::...|:.||:|.|.||||:|||||||||||.||||.:
Zfish   469 IQELKDNQSRLEESFDNLKSHYQRDYTDIMQALQEERFRCERLEEQLNDLTELHQNEILNLKQEL 533

  Fly   552 ADMEEKVQYQSDERLRDVNEVLENCQTRISKME-HMSQQQYVTVEGIDNSNARALVVKLINVVLT 615
            |.||||:.|||.||.||:.|.||.||||||||| ...|||.|.:||::|:.||.|:.|||||:|.
Zfish   534 ASMEEKIAYQSYERARDIQEALEACQTRISKMELQQQQQQVVQLEGLENATARTLLGKLINVLLA 598

  Fly   616 ILQVVLLLVATAAGIIMPFLKTRVRVLTTFLSICFVIFVIRQW 658
            ::.|:|:.|:|.|..::|.:|||.|.|:|.|.:..:.|:.|.|
Zfish   599 VMAVLLVFVSTVANCVVPLMKTRSRTLSTLLLVLVLAFLWRNW 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dmtn	NP_001163531.1	Tmemb_cc2	249..658	CDD:463036	187/421 (44%)
tmcc1b	NP_001073477.1	Tmemb_cc2	237..641	CDD:463036	187/421 (44%)