Protein Alignment Dmtn and tmcc2

DIOPT Version :9

• Sequence 1: NP_001163531.1
• Gene: Dmtn / 40792
• FlyBaseID: FBgn0037443
• Length: 679
• Species: Drosophila melanogaster
• Sequence 2: NP_001038384.1
• Gene: tmcc2 / 560064
• ZFINID: ZDB-GENE-091202-2
• Length: 467
• Species: Danio rerio
• Alignment Length: 496
• Identity: 201/496 - (40%)
• Similarity: 274/496 - (55%)
• Gaps: 98/496 - (19%)

  Fly   204 GGSAGTGSGLEDSRLSGNEDYYSSFVSDEFDSSKKVHRRCHERSSSVQAIDRLNTKIQCTKESIR 268
            |||.|.                   :|.|..|..::.|       :..|::.|..||....|.||
Zfish    19 GGSDGN-------------------ISVEAGSEGEIQR-------TRAALEHLQQKILKITEQIR 57

  Fly   269 QEQTARDDNVNEYLKLAASADKQQLQRIKAVFEKKNQKSAHNISQLQKKLDNYTKRAKDLQNHQF 333
            .||.||||||.||||||.:|||||..|||.||||||||||..|:.|.|||::|.|:.|:.:.:
Zfish    58 VEQEARDDNVAEYLKLAHNADKQQASRIKQVFEKKNQKSAQTIAHLHKKLEHYHKKLKETEQN-- 120

  Fly   334 QTKSQHRQPREVLRDVGQGLRNVGGNIRDGITGFSG----------------SVMSKPREFAHLI 382
               ...|||::||||:.|||::||.|:|.||:||.|                :|:|||||||.||
Zfish   121 ---GPARQPKDVLRDMQQGLKDVGANMRAGISGFGGGVVEGVKGGVSALTHTAVVSKPREFASLI 182

  Fly   383 KNKFGSADNINQMSEAELQGMQSANADVLGSERLQQVPGAGTSTGSGGGGQNNNTGGAGSGTGKF 447
            :|||||||||..|.:.    ::..:|:    |..:.:.|:.|...|                .|:
Zfish   183 RNKFGSADNIAHMKDT----LEDGHAE----ETPRALSGSATLVSS----------------PKY 223

  Fly   448 NSDNGSECSSVTSESI----PGGSGKSQSGAS----------------QYHIVLKT---LLTELA 489
            .||:  ||||.||.|.    .||:|.:.||..                .:|....:   ||..|.
Zfish   224 GSDD--ECSSATSGSAAGSNSGGAGGALSGMGAAMGSPRLDGHHHHHHHHHTSSSSWDALLEGLQ 286

  Fly   490 ERKAENEKLKERIERLETG-QKEFNNLTATLESERYRAEGLEEQINDLTELHQNEIENLKQTIAD 553
            |.|.....:::.|:.::.. |.:::.:|..|:.||||.|.||||:||||||||||:.||||.:|.
Zfish   287 EIKVGQVHMEDAIDDMKAQLQSDYSYMTQCLQEERYRYERLEEQLNDLTELHQNEMSNLKQELAS 351

  Fly   554 MEEKVQYQSDERLRDVNEVLENCQTRISKME-HMSQQQYVTVEGIDNSNARALVVKLINVVLTIL 617
            |||||.|||.||.||:.|.:|:|.|||:|:| ...|||.|.:||::|:|||||:.|||||:|.::
Zfish   352 MEEKVAYQSYERARDIQEAVESCLTRITKLELQQQQQQVVQLEGVENANARALLGKLINVILALM 416

  Fly   618 QVVLLLVATAAGIIMPFLKTRVRVLTTFLSICFVIFVIRQW 658
            .|:|:.|:|.|..|.|.:|||.||..|.....|::.:.:.|
Zfish   417 AVLLVFVSTMANFITPLMKTRARVGATVALALFLVTLWKHW 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dmtn	NP_001163531.1	Tmemb_cc2	253..658	CDD:287269	191/445 (43%)
tmcc2	NP_001038384.1	Tmemb_cc2	42..457	CDD:287269	191/445 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170573445
Domainoid	1	1.000	321	1.000	Domainoid score	I1205
eggNOG	1	0.900	-	-		E1_KOG3850
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	321	1.000	Inparanoid score	I2497
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1175041at2759
OrthoFinder	1	1.000	-	-		FOG0001642
OrthoInspector	1	1.000	-	-		otm24987
orthoMCL	1	0.900	-	-		OOG6_105734
Panther	1	1.100	-	-	LDO	PTHR17613
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3682
SonicParanoid	1	1.000	-	-		X1199
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.790