Protein Alignment Dmtn and tmcc2

DIOPT Version :10

• Sequence 1: NP_001163531.1
• Gene: Dmtn / 40792
• FlyBaseID: FBgn0037443
• Length: 679
• Species: Drosophila melanogaster
• Sequence 2: XP_073792684.1
• Gene: tmcc2 / 560064
• ZFINID: ZDB-GENE-091202-2
• Length: 468
• Species: Danio rerio
• Alignment Length: 496
• Identity: 201/496 - (40%)
• Similarity: 274/496 - (55%)
• Gaps: 98/496 - (19%)

  Fly   204 GGSAGTGSGLEDSRLSGNEDYYSSFVSDEFDSSKKVHRRCHERSSSVQAIDRLNTKIQCTKESIR 268
            |||.|.                   :|.|..|..::.|       :..|::.|..||....|.||
Zfish    20 GGSDGN-------------------ISVEAGSEGEIQR-------TRAALEHLQQKILKITEQIR 58

  Fly   269 QEQTARDDNVNEYLKLAASADKQQLQRIKAVFEKKNQKSAHNISQLQKKLDNYTKRAKDLQNHQF 333
            .||.||||||.||||||.:|||||..|||.||||||||||..|:.|.|||::|.|:.|:.:.:
Zfish    59 VEQEARDDNVAEYLKLAHNADKQQASRIKQVFEKKNQKSAQTIAHLHKKLEHYHKKLKETEQN-- 121

  Fly   334 QTKSQHRQPREVLRDVGQGLRNVGGNIRDGITGFSG----------------SVMSKPREFAHLI 382
               ...|||::||||:.|||::||.|:|.||:||.|                :|:|||||||.||
Zfish   122 ---GPARQPKDVLRDMQQGLKDVGANMRAGISGFGGGVVEGVKGGVSALTHTAVVSKPREFASLI 183

  Fly   383 KNKFGSADNINQMSEAELQGMQSANADVLGSERLQQVPGAGTSTGSGGGGQNNNTGGAGSGTGKF 447
            :|||||||||..|.:.    ::..:|:    |..:.:.|:.|...|                .|:
Zfish   184 RNKFGSADNIAHMKDT----LEDGHAE----ETPRALSGSATLVSS----------------PKY 224

  Fly   448 NSDNGSECSSVTSESI----PGGSGKSQSGAS----------------QYHIVLKT---LLTELA 489
            .||:  ||||.||.|.    .||:|.:.||..                .:|....:   ||..|.
Zfish   225 GSDD--ECSSATSGSAAGSNSGGAGGALSGMGAAMGSPRLDGHHHHHHHHHTSSSSWDALLEGLQ 287

  Fly   490 ERKAENEKLKERIERLETG-QKEFNNLTATLESERYRAEGLEEQINDLTELHQNEIENLKQTIAD 553
            |.|.....:::.|:.::.. |.:::.:|..|:.||||.|.||||:||||||||||:.||||.:|.
Zfish   288 EIKVGQVHMEDAIDDMKAQLQSDYSYMTQCLQEERYRYERLEEQLNDLTELHQNEMSNLKQELAS 352

  Fly   554 MEEKVQYQSDERLRDVNEVLENCQTRISKME-HMSQQQYVTVEGIDNSNARALVVKLINVVLTIL 617
            |||||.|||.||.||:.|.:|:|.|||:|:| ...|||.|.:||::|:|||||:.|||||:|.::
Zfish   353 MEEKVAYQSYERARDIQEAVESCLTRITKLELQQQQQQVVQLEGVENANARALLGKLINVILALM 417

  Fly   618 QVVLLLVATAAGIIMPFLKTRVRVLTTFLSICFVIFVIRQW 658
            .|:|:.|:|.|..|.|.:|||.||..|.....|::.:.:.|
Zfish   418 AVLLVFVSTMANFITPLMKTRARVGATVALALFLVTLWKHW 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dmtn	NP_001163531.1	Tmemb_cc2	249..658	CDD:463036	192/449 (43%)
tmcc2	XP_073792684.1	None