Protein Alignment Dmtn and Tmcc3

DIOPT Version :9

• Sequence 1: NP_001163531.1
• Gene: Dmtn / 40792
• FlyBaseID: FBgn0037443
• Length: 679
• Species: Drosophila melanogaster
• Sequence 2: XP_036011707.1
• Gene: Tmcc3 / 319880
• MGIID: 2442900
• Length: 518
• Species: Mus musculus
• Alignment Length: 475
• Identity: 169/475 - (35%)
• Similarity: 241/475 - (50%)
• Gaps: 103/475 - (21%)

  Fly   254 DRLNTKIQCTKESIRQEQTARDDNVNEYLKLAASADKQQLQRIKAVFEKKNQKSAHNISQLQKKL 318
            |.|..||....|.|:.|||:||.||.|||||.:||||||..|||.|||||||||||:|:||||||
Mouse    69 DSLRQKILKVTEQIKIEQTSRDGNVAEYLKLVSSADKQQAGRIKQVFEKKNQKSAHSIAQLQKKL 133

  Fly   319 DNYTKRAKDLQNHQFQTKSQHRQPREVLRDVGQGLRNVGGNIR----------DGITGFSGS--- 370
            :.|.::.::::.:.. |:|.....::.|:::...|::.....|          ..:.|.|.:
Mouse   134 EQYHRKLREIEQNGV-TRSSKDISKDSLKEIHHSLKDAHVKSRTAPHCLESSKSSMPGVSLTPPV 197

  Fly   371 -VMSKPREFAHLIKNKFGSADNI----NQMSEAELQGMQSANADVLGSERLQQVPGAGTSTGSGG 430
             |.:|.||||:||:|||||||||    |.:.|...:....|..   ||..:...|
Mouse   198 FVFNKSREFANLIRNKFGSADNIAHLKNSLEEFRPEASPRAYG---GSATIVNKP---------- 249

  Fly   431 GGQNNNTGGAGSGTGKFNSDNGSECSSVTSESIPG------GSGKSQSGASQYHIVLKTLLTELA 489
                           |:.||:  ||||.||.|...      |:|.:.:..||..|.  .::.||.
Mouse   250 ---------------KYGSDD--ECSSGTSGSADSNGNQSFGAGGTSTLDSQGKIA--KIMEELR 295

  Fly   490 ERKAENEKLKERIERLETG-QKEFNNLTATLESERYRA--------------------------- 526
            |.|....:|.|.||.|:.. ::|:..::.||:.||||.
Mouse   296 EIKVTQTQLAEDIEALKVQFKREYGFISQTLQEERYRKTVFQGMKTSQGPQDKKGHHSRPRRWNT 360

  Fly   527 --------------EGLEEQINDLTELHQNEIENLKQTIADMEEKVQYQSDERLRDVNEVLENCQ 577
                          |.||:|::|||||||:|..||||.:|..||||.||:.||.||:.|.||:||
Mouse   361 CAPCSLRLLSLLRYERLEDQLHDLTELHQHETANLKQELASAEEKVAYQAYERSRDIQEALESCQ 425

  Fly   578 TRISKME-HMSQQQYVTVEGIDNSNARALVVKLINVVLTILQVVLLLVATAAGIIMPFLKTRVRV 641
            |||||:| |..:||.:..:.:   ||:.|:.|.|||||..:.|:|:.|:|.|..:.|.:|:|..:
Mouse   426 TRISKLELHQQEQQTLQTDAV---NAKVLLGKCINVVLAFMTVILVCVSTLAKFVSPMMKSRSHI 487

  Fly   642 LTTFLSICFVIFVIRQWPDV 661
            |.||.::..:....:.|..:
Mouse   488 LGTFFAVTLLAIFCKNWDHI 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dmtn	NP_001163531.1	Tmemb_cc2	253..658	CDD:287269	168/470 (36%)
Tmcc3	XP_036011707.1	Tmemb_cc2	65..504	CDD:402057	168/470 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167830707
Domainoid	1	1.000	324	1.000	Domainoid score	I1191
eggNOG	1	0.900	-	-		E1_KOG3850
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	324	1.000	Inparanoid score	I2474
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1175041at2759
OrthoFinder	1	1.000	-	-		FOG0001642
OrthoInspector	1	1.000	-	-		otm42317
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR17613
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3682
SonicParanoid	1	1.000	-	-		X1199
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.890