Protein Alignment Dmtn and tmcc1

DIOPT Version :10

• Sequence 1: NP_001163531.1
• Gene: Dmtn / 40792
• FlyBaseID: FBgn0037443
• Length: 679
• Species: Drosophila melanogaster
• Sequence 2: XP_012816108.1
• Gene: tmcc1 / 100170168
• XenbaseID: XB-GENE-5881367
• Length: 643
• Species: Xenopus tropicalis
• Alignment Length: 614
• Identity: 222/614 - (36%)
• Similarity: 319/614 - (51%)
• Gaps: 131/614 - (21%)

  Fly   126 NTVTGSLGSAGVVARGFRSHSPTHRRRSRERQRRTHGSDQGG---------LLAYSGLVGVNDMT 181
            |.|...:.:...|.||      :..:::|:.:..|.||.|.|         :|::.|....:..|
 Frog    94 NRVLQQIRAPPKVKRG------SSLQQNRKAKPNTRGSPQIGRRSAQDIMAVLSHPGRPRSSSTT 152

  Fly   182 DFLGPQQGGGGGGGGGGGGGGGGGSAGTGSGLE---DSRLS-------------GNEDYYSSFVS 230
            |                        |.:.|.||   .|.||             ||....||.||
 Frog   153 D------------------------AHSTSALEVPNSSYLSGDDSVERLDRLEGGNLSQASSMVS 193

  Fly   231 ---------DEFDSSKKVHRRCHERSSSVQAIDRLNTKIQCTKESIRQEQTARDDNVNEYLKLAA 286
                     |..|.:....|       :..||.:|..||....|.|:.|||||||||.||||||.
 Frog   194 SGADGMLSTDAVDGTPDPQR-------TKAAILQLQQKILKLTEQIKIEQTARDDNVAEYLKLAN 251

  Fly   287 SADKQQLQRIKAVFEKKNQKSAHNISQLQKKLDNYTKRAKDLQNHQFQTKSQHRQPREVLRDVGQ 351
            :||:||..|||.|||||||||:.||.||||||::|.::.::::.:...     |||::|.||:.|
 Frog   252 NADRQQGARIKQVFEKKNQKSSQNILQLQKKLEHYRRKLREVEQNGIA-----RQPKDVFRDMHQ 311

  Fly   352 GLRNVGG-----------NIRDGITGFS-------GSVMSKPREFAHLIKNKFGSADNINQMSE- 397
            ||::||.           ::|.|::..|       |:|:|||||.|.|::|:|||:|||..:.:
 Frog   312 GLKDVGARVTGFSEGVVDSVRGGLSSISQATHSAAGAVVSKPREIASLLRNRFGSSDNIASLDDP 376

  Fly   398 ---AELQGMQSANADVLGSERLQQVPGAG-----TSTGSGGGGQNNNTGGAGSGTGKFNSDNGSE 454
               :.|||...|....||: .||..|..|     :|..||..|.|:.:||.|.|.|...|   |.
 Frog   377 SILSTLQGDDLAPGKGLGN-MLQASPKYGSEEDCSSATSGSFGANSTSGGQGGGGGGAGS---SR 437

  Fly   455 CSSVTSESIPGGSGKSQSGASQYHIVLKTLLTELAERKAENEKLKERIERLETG-QKEFNNLTAT 518
            .:::.::::.|           :.:||.    |:.|.:....:|:|.:|.|::. |::::.:..:
 Frog   438 TNTLDTQALTG-----------FDVVLH----EIQEIREAQGQLEESLEGLKSQYQRDYSYILQS 487

  Fly   519 LESERYRAEGLEEQINDLTELHQNEIENLKQTIADMEEKVQYQSDERLRDVNEVLENCQTRISKM 583
            |:.||:|.|.||||:|||||||||||.||||.:|.||||:.|||.||.||:.|.||.||||||||
 Frog   488 LQEERFRCERLEEQLNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKM 552

  Fly   584 E-HMSQQQYVTVEGIDNSNARALVVKLINVVLTILQVVLLLVATAAGIIMPFLKTRVRVLTTFLS 647
            | ...|||.|.:||::|:.||.|:.||||::|.::.|||:.|:|.|..::|.||||.|.:.|.|.
 Frog   553 ELQQQQQQVVQLEGLENATARNLLGKLINILLALMAVVLVFVSTVANCVVPLLKTRGRTIGTLLL 617

  Fly   648 ICFVIFVIRQWPDVQDIGSGLVRHLKQSL 676
            :.....:.:.|       .....||:|.|
 Frog   618 VLVAAILWKHW-------DSFSVHLEQLL 639

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dmtn	NP_001163531.1	Tmemb_cc2	249..658	CDD:463036	186/437 (43%)
tmcc1	XP_012816108.1	Tmemb_cc2	214..628	CDD:463036	186/437 (43%)