DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gzl and AT1G71980

DIOPT Version :9

Sequence 1:	NP_001097695.1	Gene:	gzl / 40791	FlyBaseID:	FBgn0037442	Length:	536	Species:	Drosophila melanogaster
Sequence 2:	NP_177343.2	Gene:	AT1G71980 / 843529	AraportID:	AT1G71980	Length:	448	Species:	Arabidopsis thaliana

Alignment Length:	500	Identity:	143/500 - (28%)
Similarity:	216/500 - (43%)	Gaps:	100/500 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LLGLCLVCHEATLVGGHVLVYRKATSQLIEEFNDLPAQFGPNLPSNGLKVYVVPARRPYYGCDSL 75
            |:.|..||..:.|....|::.|   :.:...|:|:.|.|.|::...| ::.||....|...|.:|
plant     5 LVLLLYVCTVSCLASSKVILMR---NNITLSFDDIEANFAPSVKGTG-EIGVVYVAEPLDACQNL 65

  Fly    76 DRPPHLKYPPSAKFVALVARGECVFERKIRVAQNASYSAVIVYNNEGDDLEQMSAENITGIRIPS 140
            ...|......::.|| |:.||.|.||.|:|.||.|.:.|.|:|:||........|.|..||||.:
plant    66 MNKPEQSSNETSPFV-LIVRGGCSFEEKVRKAQRAGFKAAIIYDNEDRGTLIAMAGNSGGIRIHA 129

  Fly   141 VFVGHTTGKALATYF---TTEVVLIINDELP----FNINTQLILPFSILIGMCFIIMVIYMIYKC 198
            |||...||:.|..|.   .|:|.||.:.|..    ..::...:|..|.::..||.:....:..:.
plant   130 VFVTKETGEVLKEYAGFPDTKVWLIPSFENSAWSIMAVSFISLLAMSAVLATCFFVRRHRIRRRT 194

  Fly   199 IREQRRLRRHRLPKSMLKKLPVLRYTK-NNANNKYDTCVICLEDFIEDDKLRVLPCSHPYHTHCI 262
            .|..|....|.:.:.::|.:|.|.::. :..|....||.|||||:...||||:|||.|.:|..|:
plant   195 SRSSRVREFHGMSRRLVKAMPSLIFSSFHEDNTTAFTCAICLEDYTVGDKLRLLPCCHKFHAACV 259

  Fly   263 DPWLTENRRVCPICKRKVFTKGEARASRSRQPSLDNVTDTDDDTTPLLQQQQSNGRQVGQVSSAS 327
            |.|||..|..||:|||      :||.|....|:        .::||||             |||:
plant   260 DSWLTSWRTFCPVCKR------DARTSTGEPPA--------SESTPLL-------------SSAA 297

  Fly   328 SAGGAAGSSSSV-AAAAVAGTTRHGTFRRGHAGRNPFEESQSSDDENALLASTVRPATSSGAHER 391
            |:..::...||| ::|.:.|.:         .|..|...|.|             ||.:|.::.|
plant   298 SSFTSSSLHSSVRSSALLIGPS---------LGSLPTSISFS-------------PAYASSSYIR 340

  Fly   392 INPFDRAPNLPAHLAEQLTESRRSVWSRINFASFFRRQPAVISVAAP---PYLERVESGTSAMGL 453
                         .:.|.:.:|||....::.:|...||.|.....:|   .|:..:.|..| :|.
plant   341 -------------QSFQSSSNRRSPPISVSRSSVDLRQQAASPSPSPSQRSYISHMASPQS-LGY 391

  Fly   454 PVTGTI------------AVASPA----SNNILNP----NLSGSF 478
            |.....            :.||||    ||..|||    ..:|:|
plant   392 PTISPFNTRYMSPYRPSPSNASPAMAGSSNYPLNPLRYSESAGTF 436

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gzl	NP_001097695.1	PA_C_RZF_like	14..171	CDD:239038	54/163 (33%)
gzl	NP_001097695.1	zf-RING_2	233..277	CDD:290367	24/43 (56%)
AT1G71980	NP_177343.2	PA_C_RZF_like	11..161	CDD:239038	53/154 (34%)
AT1G71980	NP_177343.2	zf-RING_2	230..274	CDD:290367	24/43 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	70	1.000	Domainoid score	I3392
eggNOG	1	0.900	-	-		E1_KOG4628
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	151	1.000	Inparanoid score	I1703
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1487241at2759
OrthoFinder	1	1.000	-	-		FOG0001489
OrthoInspector	1	1.000	-	-		otm2691
orthoMCL	1	0.900	-	-		OOG6_103040
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X670
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.730