DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gzl and rnf150b

DIOPT Version :9

Sequence 1:	NP_001097695.1	Gene:	gzl / 40791	FlyBaseID:	FBgn0037442	Length:	536	Species:	Drosophila melanogaster
Sequence 2:	NP_001017554.1	Gene:	rnf150b / 792211	ZFINID:	ZDB-GENE-050417-470	Length:	419	Species:	Danio rerio

Alignment Length:	385	Identity:	90/385 - (23%)
Similarity:	147/385 - (38%)	Gaps:	119/385 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 YGCDSLDR----------PPHLKY--PPSAKF--------VALVARGECVFERKIRVAQNASYSA 114
            ||..||.|          .||.::  .||.:|        :||::||.|.::.|||.|...:.||
Zfish    66 YGEHSLKREARGVLAMPAAPHDRHACDPSGRFTPRAHGAWIALISRGNCTYKDKIRHAVGHNASA 130

  Fly   115 VIVYN------NEGDDLEQMSAENITGIRIPSVFVGHTTGKALATYFTTEVVLI----INDELPF 169
            |:::|      ||...:......::..|.||     ...|:        |:||:    |...:..
Zfish   131 VVIFNVGSSNPNETITMPHQGISDVVAIMIP-----EPKGR--------ELVLLMERNITVHMHI 182

  Fly   170 NINTQLILPF-----SILIGMCFIIMVI----YMIYKCI----------REQRRLRRHRLPKSML 215
            .|.|:.:..:     .:.:.:.|||::|    ::::..|          |.||||  ....|..:
Zfish   183 TIGTRNLQKYVSRTSVVFVSISFIILMIISLAWLVFYYIQRFRYANARDRNQRRL--GDAAKKAI 245

  Fly   216 KKLPV--LRYTKNNANNKYDTCVICLEDFIEDDKLRVLPCSHPYHTHCIDPWLTENRRVCPICKR 278
            .:|.|  :|.......:.:|.|.:|:|.:..:|.:|:|||.|.:|..|:||||.:: |.||:||.
Zfish   246 SQLQVRTIRKGDQETESDFDNCAVCIEGYKPNDVVRILPCRHLFHKCCVDPWLVDH-RTCPMCKM 309

  Fly   279 KVFTKGEARASRSRQPSLDNVTDTDDDTTPLLQQQQSNGRQVGQVSSAS-----------SAGGA 332
            .:.                                    :.:|..|||.           :.||.
Zfish   310 NIL------------------------------------KALGLTSSAECLNELPLDYELAVGGV 338

  Fly   333 AGS----SSSVAAAAVAGTTRHGTFRRGHAGRNPFEESQSSDDENALLASTVRPATSSGA 388
            |.:    |..|.|..|.|....|. |.|...:...:....|.|......|.::|..|..:
Zfish   339 ALNAMVMSDDVMAGDVGGARDPGV-RMGGLPQVLLDSEPLSQDTMPTEQSELQPIASGSS 397

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gzl	NP_001097695.1	PA_C_RZF_like	14..171	CDD:239038	33/130 (25%)
gzl	NP_001097695.1	zf-RING_2	233..277	CDD:290367	19/43 (44%)
rnf150b	NP_001017554.1	PA_GRAIL_like	45..182	CDD:239037	33/128 (26%)
		UPF0233	<196..>221	CDD:299753	4/24 (17%)
		zf-RING_2	265..308	CDD:290367	19/43 (44%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	374..419		5/24 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1487241at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920