Protein Alignment gzl and znrf3

DIOPT Version :9

• Sequence 1: NP_001097695.1
• Gene: gzl / 40791
• FlyBaseID: FBgn0037442
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_001072864.1
• Gene: znrf3 / 780325
• XenbaseID: XB-GENE-5937936
• Length: 853
• Species: Xenopus tropicalis
• Alignment Length: 551
• Identity: 105/551 - (19%)
• Similarity: 201/551 - (36%)
• Gaps: 124/551 - (22%)

  Fly    31 YRKATSQLIEEFNDLPAQFGPNLPSNGLKVYVVPARRPYYGCDSLDRPPHLKYPPSAKFVALVAR 95
            |:..|::|...|    ::.|..:.:.|..|.:    .|...|::.|.....:|    .:|.:|..
 Frog    47 YKTHTTELQGRF----SRAGATISAEGEIVQM----HPLGLCNNNDEEDLYEY----GWVGVVKL 99

  Fly    96 GE-------C--VFERKIRVAQNASYSAVIVYNNEGDDLEQMSAENITGIRIPSVFVGHTTGKAL 151
            .:       |  |..:..|..|..:.:.:...::..|.:||::......::.|.|::     |.:
 Frog   100 EQPEMDPKPCLTVLGKAKRAVQRGATAVIFDVSDNPDAVEQLNQGLEDPLKRPVVYM-----KGM 159

  Fly   152 ATYFTTEVVLIINDELPFNINTQ--------------LILPFSILIGMCFIIMVIYMIYKCIREQ 202
            .   ..:::.|:|.:.......|              :.|.|.:::.:..:|::|.:..|..|.|
 Frog   160 D---AIKLMNIVNKQKGARARIQHRPPRQPTEYFDMGIFLAFFVVVSLVCLILLIKIKLKQRRSQ 221

  Fly   203 RRLRRHRLPKSMLKKLPVLRYTKNN--------------ANNKYDTCVICLEDFIEDDKLRVLPC 253
            ..:  :|:....|:|:...::....              :::....|.||||.:|:.::|||:||
 Frog   222 NSM--NRMAVQALEKMETRKFKAKGKVPREGSCGGLDTLSSSSTSDCAICLEKYIDGEELRVIPC 284

  Fly   254 SHPYHTHCIDPWLTENRRVCPICKRKVF--TKG-------EARASRSRQPSLDNVTDTDDDTTPL 309
            :|.:|..|:||||.:| ..||.|:..:.  .||       |..::|.||
 Frog   285 THRFHKRCVDPWLLQN-HTCPHCRHNIIEQKKGGHGPVCVENSSNRGRQ---------------- 332

  Fly   310 LQQQQS-------NGR--QVGQVSSASSAGGAAGSSSSVAAAAVAG-------TTRHGTFRRGHA 358
             ||||.       .||  :.|.:::..:........:.:....|..       ..|..||.   |
 Frog   333 -QQQQRVILPVHYPGRVQRTGPIAAYPTRTSMGPHGNPITVLTVERPLEPDLYPARTPTFL---A 393

  Fly   359 GRNPFEESQSSDDENALLASTVRPATSSG-AHERINPFDRAPNLPAHLAEQLTESRRSVWSRINF 422
            |..|.....:|...:..|.....||..:| ...|.....|..|.....::..|..:...:..:::
 Frog   394 GYRPVSLDHASSGHHCDLEHPPYPAPPAGHGFRRAKYSGRGFNNGTCYSQYETMYQHYYFQGLSY 458

  Fly   423 ASFFRRQPAVISVAAPPYLER-----VESGTSAMGLPVTGTIAVASPASNNILNPNLSGSFKDED 482
            .    .|..|....||..:|.     ..||.:.:..|....:.:|.|:|       :...:....
 Frog   459 P----HQQEVGGSQAPRVVENGHNHSFHSGNNMLYQPAPTLMHMAPPSS-------VGSCYLHSQ 512

  Fly   483 DMPPHRSIYEPIAISTPAADSATVDDSAFLQ 513
            ..  |||:........|.:||::...::..|
 Frog   513 HQ--HRSVCSGYLADVPCSDSSSSSSASSAQ 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gzl	NP_001097695.1	PA_C_RZF_like	14..171	CDD:239038	25/148 (17%)
		zf-RING_2	233..277	CDD:290367	21/43 (49%)
znrf3	NP_001072864.1	ZNRF_3_ecto	74..180	CDD:375639	18/121 (15%)
		RING-H2_ZNRF3	266..309	CDD:319713	22/43 (51%)
		RING-H2 finger (C3H2C3-type)	266..306	CDD:319713	21/40 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	583..629
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	650..673
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	685..713
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	834..853

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1487241at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920