Protein Alignment gzl and rnf150a

DIOPT Version :10

• Sequence 1: NP_649653.1
• Gene: gzl / 40791
• FlyBaseID: FBgn0037442
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_001139044.1
• Gene: rnf150a / 559804
• ZFINID: ZDB-GENE-060213-1
• Length: 418
• Species: Danio rerio
• Alignment Length: 458
• Identity: 108/458 - (23%)
• Similarity: 199/458 - (43%)
• Gaps: 95/458 - (20%)

  Fly     4 RSCQILT----LLGLC---LVCHEATLVGG--------HVLVYRKATSQLIEEFNDLPAQFGPNL 53
            ::|:.|.    ||..|   |:|.:.|:...        ::......||::..:.::. .::|.:.
Zfish     7 QACRSLALSTWLLSFCFVHLLCLDFTVAEKEEWYTAFVNITYLDPVTSEIKTDRSEC-GRYGEHS 70

  Fly    54 PSNGLKVYV-VPARRPYYGCDSLDR-P-PHLKYPPSAKFVALVARGECVFERKIRVAQNASYSAV 115
            |....:.:| :|..|  ..||...| | ||    ||..::||:|:|.|.|..|||.|...:.|||
Zfish    71 PKRDARGFVFMPQDR--QACDGNTRFPLPH----PSIPWIALIAKGNCTFREKIRHAAALNASAV 129

  Fly   116 IVYN------NEGDDLEQMSAENITGIRIPSVFVGHTTGKALATYFTTEVVLIINDELPFNINTQ 174
            :::|      |:...:......::..|.||     ...|:.:.......:.:.::    .:|.|:
Zfish   130 VIFNVGSSNSNDTITMPHHGTGDVVAIMIP-----EPKGREIMALLEKNITVAMH----ISIGTR 185

  Fly   175 LILPF-----SILIGMCFIIMVI----YMIYKCI----------REQRRLRRHRLPKSMLKKLPV 220
            .:..:     .:.:.:.||:::|    ::::..|          |.||||  ....|..:.||.|
Zfish   186 NLQKYVSRTSVVFVSISFIVLMIISLAWLVFYYIQRFRYANARDRSQRRL--GDAAKKAISKLQV 248

  Fly   221 --LRYTKNNANNKYDTCVICLEDFIEDDKLRVLPCSHPYHTHCIDPWLTENRRVCPICKRKVFTK 283
              :|......::.:|.|.:|:||:..:|.:|:|||.|.:|.:|:|||| ::.|.||:||..:.
Zfish   249 RTIRKGDKETDSDFDNCAVCIEDYKPNDVVRILPCRHVFHRNCVDPWL-QDHRTCPMCKMNIL-- 310

  Fly   284 GEARASRSRQPSLDNVTDTDDDTTPLLQQQQSNGRQVGQVSSASSAGGAAGSSSSV--AAAAVAG 346
                    :...:...||..||..|  ..:.|:|:....|:.||..  :.|.||.|  ....:.|
Zfish   311 --------KALGIPPNTDCSDDAPP--DYETSSGQPSIAVTGASEV--SVGESSLVLDQPLRITG 363

  Fly   347 TTRHGTFRRGHAGRNPFEESQS--SDDENALLASTVRPATSSGAHERINPFDRAPNLPAHLAEQL 409
            .:            :.::|..|  :|.|:..:||:.:...|......|.|.:.| .|.:.|.::.
Zfish   364 LS------------HDYQEMNSVPADAESPHIASSEQHQPSMSNDPDIMPMEIA-ELQSDLEQED 415

  Fly   410 TES 412
            .:|
Zfish   416 VKS 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gzl	NP_649653.1	PA_C_RZF_like	14..171	CDD:239038	38/176 (22%)
		RING-H2_RNF13-like	233..278	CDD:438327	21/44 (48%)
rnf150a	NP_001139044.1	PA_GRAIL_like	45..180	CDD:239037	34/150 (23%)
		RING_Ubox	257..311	CDD:473075	22/64 (34%)
		HRD1	<265..401	CDD:227568	44/162 (27%)