Protein Alignment gzl and RNF149

DIOPT Version :9

• Sequence 1: NP_001097695.1
• Gene: gzl / 40791
• FlyBaseID: FBgn0037442
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: XP_005263977.1
• Gene: RNF149 / 284996
• HGNCID: 23137
• Length: 428
• Species: Homo sapiens
• Alignment Length: 317
• Identity: 88/317 - (27%)
• Similarity: 139/317 - (43%)
• Gaps: 76/317 - (23%)

  Fly    48 QFGPNLPSNGLKVYVVPARRP---YYGCDSLDRPPHLKYPP------SAKFVALVARGECVFERK 103
            :||.:.|..|....|.....|   ..||    .|....:.|      :|.:|||||||.|.|:.|
Human    63 RFGDSSPKEGAHGLVGVPWAPGGDLEGC----APDTRFFVPEPGGRGAAPWVALVARGGCTFKDK 123

  Fly   104 IRVAQNASYSAVIVYNNE--GDDLEQMSAENITGIRIPSVFVGHTTGKALATYFTTEVVLIINDE 166
            :.||...:.|||::||.|  |:....||... || .|..:.:.:..|:        |::.::...
Human   124 VLVAARRNASAVVLYNEERYGNITLPMSHAG-TG-NIVVIMISYPKGR--------EILELVQKG 178

  Fly   167 LP----FNINTQLILPF-----SILIGMCFIIMVI----YMIYKCIREQRRL--------RRHRL 210
            :|    ..:.|:.:..|     .:.:.:.||.|:|    ::|:..|  ||.|        :.||.
Human   179 IPVTMTIGVGTRHVQEFISGQSVVFVAIAFITMMIISLAWLIFYYI--QRFLYTGSQIGSQSHRK 241

  Fly   211 -PKSMLKKLPVLRYTKNNANNKYD----TCVICLEDFIEDDKLRVLPCSHPYHTHCIDPWLTENR 270
             .|.::.:|  |.:|..:.....|    .|.:|:|:|...|.:|:|||.|.:|..||||||.::
Human   242 ETKKVIGQL--LLHTVKHGEKGIDVDAENCAVCIENFKVKDIIRILPCKHIFHRICIDPWLLDH- 303

  Fly   271 RVCPICKRKVFTK----GE---------ARASRSRQPSLDNVT------DTDDDTTP 308
            |.||:||..|...    ||         ..:...|.|:. |::      |..||::|
Human   304 RTCPMCKLDVIKALGYWGEPGDVQEMPAPESPPGRDPAA-NLSLALPDDDGSDDSSP 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gzl	NP_001097695.1	PA_C_RZF_like	14..171	CDD:239038	38/137 (28%)
		zf-RING_2	233..277	CDD:290367	21/47 (45%)
RNF149	XP_005263977.1	PA_GRAIL_like	43..185	CDD:239037	38/135 (28%)
		UPF0233	<204..>235	CDD:299753	9/32 (28%)
		zf-RING_2	267..310	CDD:290367	20/43 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4628
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1487241at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820