Protein Alignment gzl and Rnf43

DIOPT Version :9

• Sequence 1: NP_001097695.1
• Gene: gzl / 40791
• FlyBaseID: FBgn0037442
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_766036.2
• Gene: Rnf43 / 207742
• MGIID: 2442609
• Length: 784
• Species: Mus musculus
• Alignment Length: 530
• Identity: 123/530 - (23%)
• Similarity: 191/530 - (36%)
• Gaps: 147/530 - (27%)

  Fly    19 HEATLVGGHVLVYRKATSQLIEEFNDLPAQFGP----NLPSNGL---KVYVVPAR------RPYY 70
            |...::...|...|.|..:.:  ...:|.:..|    ||...|:   ...|.||.      .|.|
Mouse    27 HTGRVLAAAVESERSAEQKAV--IRVIPLKMDPTGKLNLTLEGVFAGVAEVTPAEGKLMQSHPLY 89

  Fly    71 GCDSLDRPPHLKYPPSAKFVALV-------ARGECV-FERKIRVAQNASYSAVIVYNNEGDDLEQ 127
            .|::.|..   ...|.  |:::|       |...|: ...|.|:|.....:||:....|    ::
Mouse    90 LCNASDDD---NLEPG--FISIVKLESPRRAPRPCLSLASKARMAGERGANAVLFDITE----DR 145

  Fly   128 MSAENI---TGIRIPSVFV-GHTTGKALATYFTTE--VVLIINDELPFNINTQLILPFSILIGMC 186
            .:||.:   .|:..|.|.: |....|.:...:...  .|.|...|.|...|..:.:..:: :|..
Mouse   146 SAAEQLQQPLGLTKPVVLIWGSDAAKLMEFVYKNRKAYVWIELKEPPAGANYDVWILLTV-VGTV 209

  Fly   187 FIIMVIYMIYKCIREQRRLR---RHRLPKSM-------LKKLPVLRY------------TKNNAN 229
            |:|::..::        |:|   .|..|..:       :.:|...||            ...::.
Mouse   210 FVIILASVL--------RIRCRPHHSRPDPLQQRTARAISQLATRRYQAGCRRARAEWPDSGSSC 266

  Fly   230 NKYDTCVICLEDFIEDDKLRVLPCSHPYHTHCIDPWLTENRRVCPICKRKVFTKGEARASRSRQP 294
            :....|.||||:|.|..:|||:.|.|.:|..|:||||.:: |.||:|...: .:|:   |.|:.|
Mouse   267 SSTPVCAICLEEFSEGQELRVISCLHEFHRTCVDPWLYQH-RTCPLCMFNI-VEGD---SFSQAP 326

  Fly   295 SLDNVTDTDDDTTPLLQQ--------QQSNGRQVGQVSSASSAGGAAGSSSSVAAAAVAGTTRHG 351
            :          .:|..|:        :|..|.....:.||...|.:..|        ||.|.|
Mouse   327 A----------ASPSYQEPGRRLHLIRQHPGHAHYHLPSAYLLGPSRTS--------VARTPR-- 371

  Fly   352 TFRRGHAGRNPFEESQSSDDENALLASTVRPATSSGAHERI--NPFDRAPNLPAHLAEQLTESRR 414
                    ..||..||             .|:..| .|:|:  ....|||....|||.. .....
Mouse   372 --------PRPFLPSQ-------------EPSMGS-RHQRLPRTSHLRAPEEQQHLAVS-PHPYA 413

  Fly   415 SVW--SRINFASFFRRQPAVISVA---APPYLERVESG----TSAMGLPVTGTIAVASPASNNIL 470
            ..|  :|:...|   :.||...||   |.|: |...||    |...|....|      |||::..
Mouse   414 QGWGLNRLRCTS---QHPAACPVALRRARPH-ESSGSGESYCTERSGYLADG------PASDSSS 468

  Fly   471 NPNLSGSFKD 480
            .| ..||..|
Mouse   469 GP-CHGSSSD 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gzl	NP_001097695.1	PA_C_RZF_like	14..171	CDD:239038	38/178 (21%)
		zf-RING_2	233..277	CDD:290367	21/43 (49%)
Rnf43	NP_766036.2	zf-RING_2	270..312	CDD:290367	21/42 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	364..407		18/74 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	459..478		8/26 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	516..671

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1487241at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920