DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment TfIIFalpha and RAP74

DIOPT Version :9

Sequence 1:	NP_524246.1	Gene:	TfIIFalpha / 40790	FlyBaseID:	FBgn0010282	Length:	577	Species:	Drosophila melanogaster
Sequence 2:	NP_001319914.1	Gene:	RAP74 / 826874	AraportID:	AT4G12610	Length:	649	Species:	Arabidopsis thaliana

Alignment Length:	569	Identity:	146/569 - (25%)
Similarity:	233/569 - (40%)	Gaps:	136/569 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 VQEFKIR-VPKMPKKHHVMRFNATLNVDFAQWRNVKLERENNMKEFRGMEEDQPKFGAGSEYNRD 101
            ::|:.:| .....|.:.:.||...|       .|.|...||..    .:.:|.|:   |.::...
plant    56 IREYNVRAAAPTDKNYFIGRFVTGL-------PNFKKGSENKW----SLRKDIPQ---GRQFTDA 106

  Fly   102 QREEARRKKFGIIARKYRPEAQPWILKVGGKTGK-KFKGIREGGVGENAAFYVFTHAPDGAIEAY 165
            |||:.:.|              ||||:  .:||: :::|..||  .::|.:|:.. ..:....|.
plant   107 QREKLKNK--------------PWILE--DETGQFQYQGHLEG--SQSATYYLLV-MQNKEFVAI 152

  Fly   166 PLTEWYNFQPIQRYKSLSAEEAEQEF-GRRKKVMNYFSLMLRKRLRG-------DEEEEQDPEEA 222
            |...||||..:.:||.|:.||||::. .|||....|...|::....|       |.|:|......
plant   153 PAGSWYNFNKVAQYKQLTLEEAEEKMKNRRKTADGYQRWMMKAANNGPALFGEVDNEKESGGTSG 217

  Fly   223 KLIKAATKKS----KELKITDM-DEWIDSEDESDSEDEEDKKKKEQEDSDDGKAKGKGKKGADKK 282
            ...:...|.|    :|..::|. ||  |.|:|:..:......:|..:|.|:     :|.:|.|
plant   218 GGGRGRKKSSGGDEEEGNVSDRGDE--DEEEEASRKSRLGLNRKSNDDDDE-----EGPRGGD-- 273

  Fly   283 KKKRDVDDEAFEESDDGDEEGREMDYDTSSSEDEP---DPEAKVDKDMKGVAEEDALRKLLTSDE 344
               .|:||:..|:.||.:.|      :..:.:||.   |||.:.|              ||..:.
plant   274 ---LDMDDDDIEKGDDWEHE------EIFTDDDEAVGNDPEERED--------------LLAPEI 315

  Fly   345 EEDDEKKSDESDKEDADGEKKKKDKGKDEVSKDKKKKKPTKDDKKGKSNGSGDSSTDFSSDSTDS 409
            ....|.|.||.|:|:     ::::.|..:..|:.||       ..||:||..:|..| ..|.:|.
plant   316 PAPPEIKQDEDDEEN-----EEEEGGLSKSGKELKK-------LLGKANGLDESDED-DDDDSDD 367

  Fly   410 EDDLSNGPPKKKVVVKDKDKEKEKEKE-SAASSKVIASSSNANKSRSATPTLSTDASKRKMNSLP 473
            |::.:.|     .|...|.||..||:. ..|.:|...|.     ....||.......|||:|...
plant   368 EEETNYG-----TVTNSKQKEAAKEEPVDNAPAKPAPSG-----PPRGTPPAKPSKGKRKLNDGD 422

  Fly   474 SDLTASD------TSNSPTS--------------TPAKRPKNEISTSLPTSFSGGKVEDYGITEE 518
            |...:|.      |.|.|.|              ||.|..|.| ..|.|.|.|......  :||:
plant   423 SKKPSSSVQKKVKTENDPKSSLKEERANTVSKSNTPTKAVKAE-PASAPASSSSAATGP--VTED 484

  Fly   519 AVRRYL-KRKPLTATELLTKFKNK-KTPVSSDRLVETMTKILKKINPVK 565
            .:|..| ::|.:|..:|:::||.: ||  ..|:  .....||:||:.::
plant   485 EIRAVLMEKKQVTTQDLVSRFKARLKT--KEDK--NAFANILRKISKIQ 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TfIIFalpha	NP_524246.1	TFIIF_alpha	37..577	CDD:253391	146/569 (26%)
TfIIFalpha	NP_524246.1	TFIIFa	39..199	CDD:238147	44/162 (27%)
RAP74	NP_001319914.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	108	1.000	Domainoid score	I2162
eggNOG	1	0.900	-	-		E1_KOG2393
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I2097
OMA	1	1.010	-	-		QHG55429
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR13011
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.060