Protein Alignment TfIIFalpha and gtf2f1

DIOPT Version :10

• Sequence 1: NP_524246.1
• Gene: TfIIFalpha / 40790
• FlyBaseID: FBgn0010282
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: XP_068071998.2
• Gene: gtf2f1 / 325832
• ZFINID: ZDB-GENE-030131-4557
• Length: 561
• Species: Danio rerio
• Alignment Length: 622
• Identity: 247/622 - (39%)
• Similarity: 358/622 - (57%)
• Gaps: 109/622 - (17%)

  Fly     1 MSSASKSTPSAASGSSTSAAAAAAASVASGSASSSANVQEFKIRVPK-MPKKHHVMRFNATLNVD 64
            |.:.||:|......:|||.:|...:..:.||:|||:.  |:.:|||| ..||:.:|.|||...|.
Zfish     1 MKATSKTTNHKQVINSTSYSAVMTSLGSQGSSSSSST--EYVVRVPKNTNKKYSIMAFNAGDKVS 63

  Fly    65 FAQWRNVKLERENNMKEFRGMEEDQPKFGAGSEYNRDQREEARRKKFGIIARKYRPEAQPWILKV 129
            .:.|...::||:.:.:...|.||.| :..||||:.:.|||||||||:|||.::::.|.|||||||
Zfish    64 CSTWTQARMERDMSNRRIYGEEETQ-EGAAGSEFGKKQREEARRKKYGIITKEFKVEDQPWILKV 127

  Fly   130 GGKTGKKFKGIREGGVGENAAFYVFTHAPDGAIEAYPLTEWYNFQPIQRYKSLSAEEAEQEFGRR 194
            .||.|::||||::|||.|||::|:||.:.|||.||:|:..||||.|..::::|:|||||:|:|||
Zfish   128 NGKAGRRFKGIKKGGVTENASYYIFTQSADGAFEAFPVHAWYNFTPQAKHRTLTAEEAEEEWGRR 192

  Fly   195 KKVMNYFSLMLRKRLR------GDEEEEQDPEEAKLIKAATKKSK-----ELKITDMDEWID-SE 247
            .||:|:||:||::|||      |||:||:..      |.|.||.|     :|:|.|::|.:: |.
Zfish   193 NKVVNHFSIMLQRRLREQERGGGDEDEEEGE------KGAKKKKKGGRGGDLRIHDLEEDLEMSS 251

  Fly   248 DES-----DSEDEEDKKKKEQEDSDDGKAKGKGKKGADKKKKKRDVDDEAFEESDDGDEEGREMD 307
            |||     |.||:|.|.|.::|         ||.||..|||||:..|.|.||:|||||.||.|:|
Zfish   252 DESDGSNGDGEDDEAKAKAKKE---------KGAKGKGKKKKKKGSDLEGFEDSDDGDFEGLEVD 307

  Fly   308 Y--DTSSSEDEPDPEAKVDK--DM-KGVAEEDALRKLLTSDEEEDDEKKSDESDKEDADGEKKKK 367
            |  |.||||:|...:.|.:|  |: ||:.|      :..|:||.::|.|::|.:||    |::::
Zfish   308 YMSDESSSEEEEPEKTKPNKGEDVPKGIDE------MSESEEESEEETKNEEENKE----EEEEE 362

  Fly   368 DKGKDEVSKDKKKKKPTKDDKKGKSNGSGDSSTDFSSDSTDSEDDLSNG--------PPKKKVVV 424
            |..|..|..:|||||        .|:|..|||.|     :|.|.:.::.        |||
Zfish   363 DGKKTPVQVEKKKKK--------DSSGESDSSED-----SDIEGEAASALFMVKKRTPPK----- 409

  Fly   425 KDKDKEKEKEKESAASSKVIASSSNANKSRSATPTLSTDASKRKMNSLPSDLTAS--DTSNSPTS 487
                  :...:.||.||:        ..||..||::...|:...:.:..|.|...  .|:...:.
Zfish   410 ------RGGGRGSAGSSR--------TGSRPGTPSIDNAATSNTLRAAASKLEQGKRQTTVPSSE 460

  Fly   488 TP-AKRPKNEISTSLPTSFSG--------GK----VEDYGITEEAVRRYLKRKPLTATELLTKFK 539
            || |||.|.|.|   |.|.||        ||    ..|..:||:||||||.|||:|..:||.||:
Zfish   461 TPAAKRLKMEPS---PQSSSGKSTPQPASGKSTPSASDVLLTEDAVRRYLIRKPMTTKDLLKKFQ 522

  Fly   540 NKKTPVSSDRLVETMTKILKKINPVKHTIQGKMYLWI 576
            .|:|.:||::.|..:.:|||::||.:..|..||:.::
Zfish   523 TKRTGLSSEQTVNVLAQILKRLNPERKNINDKMHFYL 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TfIIFalpha	NP_524246.1	TFIIF_alpha	37..577	CDD:310411	234/586 (40%)
gtf2f1	XP_068071998.2	None