Protein Alignment CG1024 and ZNF142

DIOPT Version :10

• Sequence 1: NP_001138014.2
• Gene: CG1024 / 40789
• FlyBaseID: FBgn0027514
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_001353219.1
• Gene: ZNF142 / 7701
• HGNCID: 12927
• Length: 1887
• Species: Homo sapiens
• Alignment Length: 607
• Identity: 129/607 - (21%)
• Similarity: 208/607 - (34%)
• Gaps: 188/607 - (30%)

  Fly     4 KMSRNVTLSDEQSRLN-----ARLEAHMV---------YICPECGKAFRTQAEWRQHL------- 47
            |..::.|..|.|..::     .|||..:|         ::||||.:.|:.:....:||
Human   325 KEEKSDTQKDSQKAVDKGQGAQRLEGDVVSGTESLFKTHMCPECKRCFKKRTHLVEHLHLHFPDP 389

  Fly    48 -----NTKHDYLKKTYSDFNFI-QIDERFHECQLC-FKWVENAHKTIALLQYHYFMHLE----HS 101
                 |.:..:..|:....:.: ::.|:.|.|.|| :..||..    ||.::...||.:    :|
Human   390 SLQCPNCQKFFTSKSKLKTHLLRELGEKAHHCPLCHYSAVERN----ALNRHMASMHEDISNFYS 450

  Fly   102 ETYRCVHCRMAYTRRRALNVHLLDTHMREIEKYENKLRQMKRQQAKPTTAAAPAGNAEKPMAVK- 165
            :||.|..||..:...:||..||                       |..||||    |.:|:.::
Human   451 DTYACPVCREEFRLSQALKEHL-----------------------KSHTAAA----AAEPLPLRC 488

  Fly   166 -PRGRPKGSTNRKQNDLLQKALMDID----LNTEMEKSPVTALAAPVNEPKPISNVSELNLDRCL 225
             ..|....:.:||   ...|.|.:..    :.......|:....|...|....|:.: .:...|.
Human   489 FQEGCSYAAPDRK---AFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSHYA-FHCPHCD 549

  Fly   226 NAYED--IVRKEEKEVVPKYDDELDALCKEFFDDGPSA-----GKGEANEE-QQQDDAHLQQGNQ 282
            .|..:  :.||.:|:..|. .:||......|....|.|     ||..|:|: .|..:.:....::
Human   550 FACSNKHLFRKHKKQGHPG-SEELRCTFCPFATFNPVAYQDHVGKMHAHEKIHQCPECNFATAHK 613

  Fly   283 EVVIIEIDALGKEEVAQLKKEMKSDPISQPTKRRRISTTPSRD---SDTEMSTNGLTKLISYLCP 344
            .|:|               :.|......:|.|......| .||   ....|.|:..||  .|:|.
Human   614 RVLI---------------RHMLLHTGEKPHKCELCDFT-CRDVSYLSKHMLTHSNTK--DYMCT 660

  Fly   345 KCGKEIASMDGWRAHVFKKHDFEHIIE------------------NSFKILESGRKAMC----LQ 387
            :||    .:..|: |..:.|..:|..:                  :|.|:...|:..||    ..
Human   661 ECG----YVTKWK-HYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQGKSLMCEVCAFA 720

  Fly   388 CREVQPTTVRSQLQKH-CFKHLP----------YRSY---------------------LKCTLCD 420
            |:.      :.:|||| ..:|.|          |.||                     ..|.|||
Human   721 CKR------KYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCALCD 779

  Fly   421 RTKTSTSKILNHIRYNH-----QEELQRKNKTQLLIKPEPMWASP------NKSGQ-AAMADDAG 473
            ....|.:.:|.|.|..|     .:..|.:..:|   :||.....|      ..|.| :|..:..|
Human   780 YRTFSNTTLLFHKRKAHGYVPGDQAWQLRYASQ---EPEGAMQGPTPPPDSEPSNQLSARPEGPG 841

  Fly   474 SE-----DDQGEQAVCEHCDRV 490
            .|     |...:||:.|..:.|
Human   842 HEPGTVVDPSLDQALPEMSEEV 863

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1024	NP_001138014.2	C2H2 Zn finger	30..51	CDD:275368	8/32 (25%)
		C2H2 Zn finger	73..100	CDD:275368	9/31 (29%)
		C2H2 Zn finger	106..123	CDD:275368	5/16 (31%)
ZNF142	NP_001353219.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..23
		C2H2 Zn finger	365..385	CDD:275368	7/19 (37%)
		C2H2 Zn finger	393..413	CDD:275368	2/19 (11%)
		C2H2 Zn finger	421..438	CDD:275368	7/20 (35%)
		C2H2 Zn finger	455..475	CDD:275368	8/42 (19%)
		C2H2 Zn finger	545..566	CDD:275368	5/20 (25%)
		C2H2 Zn finger	574..595	CDD:275368	5/20 (25%)
		zf-H2C2_5	601..625	CDD:404746	4/38 (11%)
		C2H2 Zn finger	603..623	CDD:275368	3/34 (9%)
		C2H2 Zn finger	631..651	CDD:275368	4/20 (20%)
		C2H2 Zn finger	659..679	CDD:275368	6/24 (25%)
		C2H2 Zn finger	687..707	CDD:275368	2/19 (11%)
		C2H2 Zn finger	714..731	CDD:275368	5/22 (23%)
		PHA03247	928..>1219	CDD:223021
		C2H2 Zn finger	1306..1353	CDD:275368
		C2H2 Zn finger	1373..1394	CDD:275368
		C2H2 Zn finger	1402..1422	CDD:275368
		C2H2 Zn finger	1430..1451	CDD:275368
		C2H2 Zn finger	1626..1646	CDD:275368
		C2H2 Zn finger	1654..1674	CDD:275368
		C2H2 Zn finger	1682..1702	CDD:275368
		zf-H2C2_2	1694..1718	CDD:463886
		C2H2 Zn finger	1710..1730	CDD:275368
		zf-H2C2_2	1723..1747	CDD:463886
		C2H2 Zn finger	1738..1759	CDD:275368
		C2H2 Zn finger	1767..1787	CDD:275368
		C2H2 Zn finger	1795..1815	CDD:275368
		C2H2 Zn finger	1823..1843	CDD:275368