DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1024 and CG30431

DIOPT Version :9

Sequence 1:	NP_001138014.2	Gene:	CG1024 / 40789	FlyBaseID:	FBgn0027514	Length:	543	Species:	Drosophila melanogaster
Sequence 2:	NP_610211.1	Gene:	CG30431 / 35549	FlyBaseID:	FBgn0050431	Length:	418	Species:	Drosophila melanogaster

Alignment Length:	492	Identity:	93/492 - (18%)
Similarity:	148/492 - (30%)	Gaps:	190/492 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    96 MHLEHSETYRCVHCRMAYTRRRALNVHLLDTHMREIEKYENKLRQMKRQQAKPTTAAAPA----- 155
            :.|||.:....|.|.:...|     :|......|..|..|..|| |:.:..|.|.|...|
  Fly    44 LRLEHGDNLTDVICDLCLRR-----LHDARDFQRRCEHSEQVLR-MRHEHWKHTVAVGDALALDD 102

  Fly   156 ---------GNAEKPMAVKPRGRPKGSTNRKQNDLLQKALMDIDLNTEMEKSPVTALAAPVNEPK 211
                     |:.|.||:|                                         |:...|
  Fly   103 VLECLEREVGSLEGPMSV-----------------------------------------PLQASK 126

  Fly   212 PISNVSEL-------NLDRCLNAYEDIVRKEEKEVVPKYDDELDALCKEFFDDGPSAGKGEANEE 269
            |:::|:.|       :||     ::|....|..  :|.|.:.             |...|..|
  Fly   127 PVAHVAPLMETVDFESLD-----FQDSSHSEHD--IPSYWES-------------SVDSGSLN-- 169

  Fly   270 QQQDDAHLQQGNQEVVIIE------------IDALGKEEVAQLK--------KEMKSDPISQPTK 314
                ..|.|....|:..:|            .||..|.::.:.:        ||.|:.....|.
  Fly   170 ----TPHHQPETAELFAVEPPTPPESSEEPAPDAAEKPKMRRARPRQDNVKPKERKASGAVHPR- 229

  Fly   315 RRRISTTPSRDSDTEMSTNGLTKL----------ISYLCPKCGKEIASMDGWRAHVFKKHDFEHI 369
                |..|..:.:.:.:.|...||          :.|.|.:|.|..||....|.||...|..|
  Fly   230 ----SLHPCPECEKKFTRNFQLKLHMTAVHGMGEMRYQCEECRKNFASRHSLRYHVKSVHSTE-- 288

  Fly   370 IENSFKILESGRKAMCLQC--REVQPTTVRSQLQKHCFKHLPYRSYLKCTLCDRTKTSTSKILNH 432
                       |...|..|  |.:..|.:.|.|:.|..:..|  ...:|..|.::..:.|.:..|
  Fly   289 -----------RPFGCQHCDRRFILRTQLLSHLRTHTGEAKP--RIFECQRCSKSWPTKSDLRTH 340

  Fly   433 IRYNHQEELQRKNK---------------TQLLIKPEPMWASPNKSGQAAMADDAGSEDDQGEQA 482
            :| :|...::|..|               :.||:          .:|:...|
  Fly   341 MR-SHNPNMERPFKCDRCSKAFFTRGHLNSHLLV----------HTGEKPFA------------- 381

  Fly   483 VCEHCDRVFRSKWRYERHIASCRRSGAGKSVEGTVEA 519
             ||:||:.::|......|:....    ...:|..:||
  Fly   382 -CEYCDKCYQSVGNLNNHMVRLH----ADIIEAQLEA 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1024	NP_001138014.2	C2H2 Zn finger	30..51	CDD:275368
		C2H2 Zn finger	73..100	CDD:275368	1/3 (33%)
		C2H2 Zn finger	106..123	CDD:275368	3/16 (19%)
CG30431	NP_610211.1	zf-AD	11..82	CDD:285071	10/42 (24%)
		C2H2 Zn finger	234..255	CDD:275368	3/20 (15%)
		C2H2 Zn finger	264..285	CDD:275368	8/20 (40%)
		C2H2 Zn finger	293..313	CDD:275368	6/19 (32%)
		zf-C2H2_8	305..373	CDD:292531	13/70 (19%)
		C2H2 Zn finger	324..344	CDD:275368	5/20 (25%)
		C2H2 Zn finger	354..374	CDD:275368	2/29 (7%)
		zf-H2C2_2	366..389	CDD:290200	8/46 (17%)
		C2H2 Zn finger	382..403	CDD:275368	6/20 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100