Protein Alignment CG42564 and CRISPLD2

DIOPT Version :10

• Sequence 1: NP_649651.2
• Gene: CG42564 / 40788
• FlyBaseID: FBgn0260766
• Length: 500
• Species: Drosophila melanogaster
• Sequence 2: NP_113664.1
• Gene: CRISPLD2 / 83716
• HGNCID: 25248
• Length: 497
• Species: Homo sapiens
• Alignment Length: 322
• Identity: 71/322 - (22%)
• Similarity: 105/322 - (32%)
• Gaps: 92/322 - (28%)

  Fly    37 GSQGQEEPGNSSSTELPDYCDPSLCHKELKHVACNASIELHDKCSLDAELIVISPKVERFLLRRF 101
            ||||...|..:...||..    ...|.| .|.....:|...||    .|::::           .
Human    19 GSQGYLLPNVTLLEELLS----KYQHNE-SHSRVRRAIPREDK----EEILML-----------H 63

  Fly   102 NELRDSVAKGGFNGLSPASRMGTLKWNPELAYLAEFNVRDCVLRHDECRNTKFTQNAGQTVG--- 163
            |:||..|.       ..||.|..:.|:.||...|......|:..|..   |....:.||.:|
Human    64 NKLRGQVQ-------PQASNMEYMTWDDELEKSAAAWASQCIWEHGP---TSLLVSIGQNLGAHW 118

  Fly   164 --YRGIKGKLPELEDILRDI-------IGVWLREKSRTSMVNIMKYVEQESQSPKYNFLQIVLEN 219
              ||.....:....|.::|.       ...|..|:....|..              ::.|||...
Human   119 GRYRSPGFHVQSWYDEVKDYTYPYPSECNPWCPERCSGPMCT--------------HYTQIVWAT 169

  Fly   220 AESVGCAI-VQQSRHGWIQ-----TFFACNY-------GHAPVVGSPVYEPGKKAAE-------S 264
            ...:|||: ..:....|.:     .:|.|||       |.||      |:.|:..:|       |
Human   170 TNKIGCAVNTCRKMTVWGEVWENAVYFVCNYSPKGNWIGEAP------YKNGRPCSECPPSYGGS 228

  Fly   265 CKTGANPKYAHLCAESEVYEKVTPKAGNASSPEIKTRTLGKRDFVMLNGENADGTPPAEGGA 326
            |:.       :||...|.|   |||.......|::|..:.:.:.|.|.......|.|.:..|
Human   229 CRN-------NLCYREETY---TPKPETDEMNEVETAPIPEENHVWLQPRVMRPTKPKKTSA 280

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42564	NP_649651.2	CAP_euk	95..245	CDD:349399	35/174 (20%)
CRISPLD2	NP_113664.1	CAP_CRISPLD2	56..201	CDD:349410	36/183 (20%)
		LCCL	286..370	CDD:128866
		LCCL	389..487	CDD:427521