Protein Alignment CRAT and YAT2

DIOPT Version :10

• Sequence 1: NP_649650.2
• Gene: CRAT / 40787
• FlyBaseID: FBgn0037440
• Length: 662
• Species: Drosophila melanogaster
• Sequence 2: NP_010941.1
• Gene: YAT2 / 856745
• SGDID: S000000826
• Length: 923
• Species: Saccharomyces cerevisiae
• Alignment Length: 766
• Identity: 157/766 - (20%)
• Similarity: 267/766 - (34%)
• Gaps: 209/766 - (27%)

  Fly    80 LPLE---ETLNRFMTTVEPL----------LTPEEFQRQKGITSEF-----LKKQGRELQ----- 121
            |||.   :||.|...::|||          |.||:.::...|..:|     .:|...:||
Yeast    26 LPLPKLCDTLQRLKESLEPLYYADGYYQHPLDPEQIEKLSSIIRDFEENPVSEKLQSKLQSYHDT 90

  Fly   122 --LLLEETGSKEKNWLAHRWLKAAYLTYRDPVTVFVSPGMTFPKQNFRDSRAFVDYTARVIYGLG 184
              ..|:|......|..:.|.::...|. |:|..|.....:....|..| |...|...||.|..|.
Yeast    91 RDCYLDELHLDINNQTSTREIQDDVLP-RNPFLVLADDALPNITQADR-SAVLVHSAARFISALK 153

  Fly   185 E-------------------FNDMVHANKIPIVKMGKNELDNSQFGKVFGTCRI--PRRGTDE-- 226
            :                   |.::....:.|:.:.|  |::|....|.:....:  |...:||
Yeast   154 QDLLPPDINATNGKPLSMAPFLNLFGTTRSPVFQRG--EVENFDLNKPYTASDLEDPDYSSDEDD 216

  Fly   227 ---------------------------IVYNPDSDYVVVIYKNHFYQLKIYSKEGKLIAAPCLAA 264
                                       |..:|||.::::|.:..:|.|::.....|:|.......
Yeast   217 NDEPTQKDFDDRKRKHEEDIFTGNGITIKRHPDSKHILIISRGQYYTLEVLDSTNKIIYTAAELT 281

  Fly   265 QLENIVLKET---QVGVPYGILTTDSRDNWAEAYEYLVETPGNRDALKTIQGALFTVSLDEG--T 324
            .:.|.::|::   :.....|.||:.|..||..|.:.|.:...|.  |..|..|||.:.|||.  .
Yeast   282 TIFNHIIKDSSGIEKSTALGSLTSHSFRNWKYARKRLQKRYPNE--LHRIDSALFVLVLDESQEE 344

  Fly   325 ILKEGEETDELI-------------------------LSLIHGSGSKINS-GNRWMDKTIQLVVN 363
            ...:|::|.::.                         .|:|:..|.::.| .:||.|| :||||.
Yeast   345 TTNDGDDTADISQMFNRTITERDKKCTSANCKRVFYGTSIINSKGHQVGSCVSRWYDK-LQLVVT 408

  Fly   364 PNGNVGFTYEHSPAEGQPI-----AMMMDYVVQKMKE----DPSFG------------------- 400
            .:......::....:|..:     .:..:.|::..::    ||.|.
Yeast   409 ADAKATVIWDSFTCDGSVVLRFTSEIYTESVLRLARDVNAGDPQFSLWPNVTQMDPETKKLMTAT 473

  Fly   401 ----QSGSQDFAP---AQKIQFSSSNKSLEKSLNVAQENVDKLADALQMKVLKFNGFGKDFIK-- 456
                ..|..:..|   ..||.:|.|| .|...:::::   .||||.:.    |:     |.::
Yeast   474 ISADGGGPSEIDPKLVVNKIDWSFSN-ILNTHVHLSE---TKLADLIS----KY-----DIVRAS 525

  Fly   457 -------KQRLG--PDSFVQMALQLAFYKMHSEPPAQYESAHLRIFDGGRTETIRSCSNESLAFS 512
                   .||||  |||.||:|||:|.|.::.......|....|.|...|:..|...|...|...
Yeast   526 IPLGRRSAQRLGVKPDSMVQVALQIAHYALYGRMVFGLEPVSTRGFKNSRSSFINIQSQALLELC 590

  Fly   513 RAMQDPNVTDQERAAKLREAVVSHQTYAKLALQGKGVDRHLLGLKLMALEH-----------SKP 566
            :.....::...::..|..:...:|....|.|..|.|.::|...||.:...|           |..
Yeast   591 QLFISSSIDGTDKLDKFIQTCETHNNMVKHAKSGVGYEKHFNALKYLFKFHDHFGIHLSGDESSA 655

  Fly   567 IPEFFKSPGFVKSSHFRMSTSQVATKYDAFMGYGPATDDGYACCYNPRDNDIILAI--------- 622
            ..:.|::|..:..|...:..:..........|..||...|:...|..:|:.:.|.:
Yeast   656 AKDLFENPLVLPFSQPELIVANCGNAATTTFGITPAVPHGFGIGYIIKDDQVDLTVTSQFRQGDR 720

  Fly   623 -------------SAWRHCPITDHLKF---VKTLEQSFFEMKNVLEKNPPE 657
                         |.||....|.|.|.   :..:....:||.|.: .|||:
Yeast   721 LMFMLSWVLGEIRSYWRMSRGTSHNKTGVKISPVVDKLYEMDNAV-NNPPK 770

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CRAT	NP_649650.2	Carn_acyltransf	79..642	CDD:459926	151/749 (20%)
YAT2	NP_010941.1	Carn_acyltransf	26..725	CDD:459926	145/718 (20%)