Protein Alignment CRAT and YAT1

DIOPT Version :10

• Sequence 1: NP_649650.2
• Gene: CRAT / 40787
• FlyBaseID: FBgn0037440
• Length: 662
• Species: Drosophila melanogaster
• Sequence 2: NP_009420.1
• Gene: YAT1 / 851285
• SGDID: S000000080
• Length: 687
• Species: Saccharomyces cerevisiae
• Alignment Length: 664
• Identity: 171/664 - (25%)
• Similarity: 288/664 - (43%)
• Gaps: 99/664 - (14%)

  Fly    72 PNLLKYHVLPLEETLNRFMTTVEPLLTPEEFQRQKG--ITSEFLKKQGRELQLLLE-----ETGS 129
            |||.:..:.||::||||::..||||....:.:|.:.  :::|.|.......:.|||     ...:
Yeast     2 PNLKRLPIPPLQDTLNRYLARVEPLQDERQNRRTRRTVLSAENLDALNTLHERLLEYDARLAESN 66

  Fly   130 KEKNWLAHRWLKAAYLTYRDPVTVFVSPGMTFPKQNFRDSRAFVDYTARVIYG------------ 182
            .|.:::...|.. |||.|...|.:.|:|  .|..|:....:...:..|:..||
Yeast    67 PESSYIEQFWYD-AYLLYDATVVLNVNP--YFQLQDDPTIKDTPETAAQGPYGAHTVQVRRAARL 128

  Fly   183 ----LGEFNDMVHANKIPIVKMGKNELDNSQFGKVFGTCRIPRRGTDE----IVYNPDSDYVVVI 239
                |.....:.|.........||..|...|:.::||:.||| .|..|    :..:..|.:||.:
Yeast   129 TTSILKFIRQIRHGTLRTDTVRGKTPLSMDQYERLFGSSRIP-PGPGEPSCHLQTDATSHHVVAM 192

  Fly   240 YKNHFYQLKIY-SKEGKLIAAPCLAAQLE----NIVLKETQVG---VPYGILTTDSRDNWAEAYE 296
            |:..||...:. ::...:.|.|   .|||    :|::.....|   .|:|:.||:||..|:...:
Yeast   193 YRGQFYWFDVLDTRNEPIFATP---EQLEWNLYSIIMDAESAGSGSAPFGVFTTESRRVWSNIRD 254

  Fly   297 YLVETPG--NRDALKTIQGALFTVSLDEGTILKEGEETDELILSLIHGSGS------------KI 347
            ||.....  |...||.|..|||.|.||:  :....::.|||..|::.|:.:            .:
Yeast   255 YLFHADDCTNWRNLKLIDSALFVVCLDD--VAFAADQQDELTRSMLCGTSTINLDPHQHQPPLNV 317

  Fly   348 NSG---NRWMDKTIQLVVNPNGNVGFTYEHSPAEGQPIAMM----------------MDYVVQKM 393
            .:|   |||.|| :||:|..||..|..:||:..:|..:..:                ...||...
Yeast   318 QTGTCLNRWYDK-LQLIVTKNGKAGINFEHTGVDGHTVLRLATDIYTDSILSFARGVTKNVVDIF 381

  Fly   394 KEDPSFGQSGSQDFAPA----------QKIQFSSSNKSLEKSLNVAQENVDKLADALQMKVLKFN 448
            .:|.  |:..|...|.|          :|:::.:.| .|:.||:.|:..:..|....:...|.|:
Yeast   382 SDDD--GKPSSSSLASAAHSANLITIPRKLEWRTDN-FLQSSLHFAETRISDLISQYEFVNLDFS 443

  Fly   449 GFGKDFIKKQ-RLGPDSFVQMALQLAFYKMHSEPPAQYESAHLRIFDGGRTETIRSCSNESLAFS 512
            .:|...||.. :..||:|||...|:|::.::......||.|..:.|..||||.|||.:.:|..|.
Yeast   444 NYGASHIKTVFKCSPDAFVQQVFQVAYFALYGRFETVYEPAMTKAFQNGRTEAIRSVTGQSKLFV 508

  Fly   513 RAMQDPNVTDQERAAKLREAVVSHQTYAKLALQGKGVDRHLLGLKLMALEHSK---PIPEFFKSP 574
            :::.|.:.:|..:...|.:|..:|....:...||.|.||||..|..:..:..|   .:|..|:..
Yeast   509 KSLLDQDASDATKIQLLHDACTAHSQITRECSQGLGQDRHLYALYCLWNQWYKDKLELPPIFRDK 573

  Fly   575 GFVKSSHFRMSTSQVATKYDAFMGYGPATDDGYACCYNPRDNDIILAISAWRHCPITDHLKFVKT 639
            .:....:..:|||..........|:||.|.:|:...|..||:.:.:.:|: ||   ....:|...
Yeast   574 SWTTMQNNVLSTSNCGNPCLKSFGFGPVTANGFGIGYIIRDHSVSVVVSS-RH---RQTARFASL 634

  Fly   640 LEQSFFEMKNVLEK 653
            :|:|..|:..:.::
Yeast   635 MEKSLLEIDRIFKR 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CRAT	NP_649650.2	Carn_acyltransf	79..642	CDD:459926	165/644 (26%)
YAT1	NP_009420.1	Carn_acyltransf	7..637	CDD:459926	165/646 (26%)