DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CRAT and cpt1b

DIOPT Version :9

Sequence 1:	NP_001287195.1	Gene:	CRAT / 40787	FlyBaseID:	FBgn0037440	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	XP_012822209.2	Gene:	cpt1b / 780223	XenbaseID:	XB-GENE-5931920	Length:	809	Species:	Xenopus tropicalis

Alignment Length:	715	Identity:	208/715 - (29%)
Similarity:	336/715 - (46%)	Gaps:	103/715 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 KTRVSPTSERILEKTEAEMKFRGNGKLLWNLTKNSLAQQ-----SPNGIAKKVLPASSYSTVQKT 66
            |:.::|.|..:|...........:|.|::..|...|...     .|:  .|..:....::...|.
Frog   132 KSILAPVSRTVLSAVIFSSGVWVSGILIYRQTLRILLSYHGWMFEPH--KKTSMKTKIWAGCMKI 194

  Fly    67 IPLEQP-------NLLKYHVLPLEETLNRFMTTVEPLLTPEEFQRQKGITSEFLKKQGRELQLLL 124
            :...||       :|.|..|.|||:|:.|::.:|.|||..::|...|.:..||.|..||:||..|
Frog   195 MSSRQPMLYSFQMSLPKLPVPPLEDTIERYLQSVRPLLDDDKFSEMKILAEEFQKDLGRKLQKYL 259

  Fly   125 EETGSKEKNWLAHRWLKAAYLTYRDPVTV----------FVSPGMTFPKQNFRDSRAFVDYTARV 179
            ........|:::..|.:..||..|.|:.|          :|:|...      :.:||     ..|
Frog   260 HLKSWWALNYVSDWWEEYIYLRGRGPIMVNSNYYAMDYLYVTPSTN------QAARA-----GNV 313

  Fly   180 IYGLGEFNDMVHANKI------PIVKMGKNELDNSQFGKVFGTCRIPRRGTDEIVYNPDSDYVVV 238
            |:.:     :::..|:      |::.:|...:.::|..::|.|.|:|...||.:.:..:|.:|.|
Frog   314 IHAM-----LLYRRKLERGLIPPVMALGIVPMCSNQMVRMFNTTRVPGVETDCLQHLVESRHVCV 373

  Fly   239 IYKNHFYQLKIYSKEGKLIAAPCLAAQLENIVLKETQVGVP----YGILTTDSRDNWAEAYEYLV 299
            .:|..:|:|.:| :.|.|:....|.:|:: .:|.::....|    ...||..:|.:||:|.....
Frog   374 YHKGRYYRLALY-ENGNLLTPRQLQSQIQ-YILDDSSPPQPGEEKLAALTAGNRVHWAQARTNFF 436

  Fly   300 ETPGNRDALKTIQGALFTVSLDEGTILKEG--EETDELILS-----LIHGSGSKINSGNRWMDKT 357
            ....||.||..::.|:|.:||||    :|.  .|.|:..||     |:||     |..|||.||:
Frog   437 SNGINRTALSCVERAVFFISLDE----EEAGYNEEDKSSLSAYSKALLHG-----NCYNRWFDKS 492

  Fly   358 IQLVVNPNGNVGFTYEHSPAEGQPIAMMMDYVVQK------MKEDPSF-GQSGSQDFAPAQKIQF 415
            ..|||..||.:|...|||.|:...|..:.::.:..      ..||.:. |.:|| ...|..::|:
Frog   493 FSLVVFRNGKLGLNAEHSWADAPIIGHLWEFTLATDCFELGYTEDGNCRGDAGS-PLPPPYRLQW 556

  Fly   416 SSSNKS---LEKSLNVAQENVDKLADALQMKVLKFNGFGKDFIKKQRLGPDSFVQMALQLAFYKM 477
            ....|.   :|:|...|:    .:||.:....|.|:.|||..|||.|..||:|.|:|||||.|:.
Frog   557 DIPPKCREVIERSYVTAK----AIADDVDFHCLCFSDFGKGLIKKCRSSPDAFFQIALQLAHYRE 617

  Fly   478 HSEPPAQYESAHLRIFDGGRTETIRSCSNESLAFSRAMQDPNVTDQERAAKLREAVVSHQTYAKL 542
            .......||::..|:|..|||||:|||:.::..|.:||:||..:.::|.|..|.|...||...:.
Frog   618 KGHFCLTYEASMTRLFRDGRTETVRSCTTQTCDFVKAMEDPTQSQEKRLALYRAAAEHHQLMYRW 682

  Fly   543 ALQGKGVDRHLLGLKLMALEHSKPIPEFFKSPGFVKSSHFRMSTSQVATK------YDAFM---- 597
            |:.|||:||||..|.::: ::......|.:.   |.|..:|:||||...:      .|.|.
Frog   683 AMTGKGIDRHLFCLYIVS-KYLGTDSAFLQK---VLSEPWRLSTSQTPQQQLKLFDLDKFPDHVS 743

  Fly   598 ---GYGPATDDGYACCY-NPRDNDIILAISAWRHCPITDHLKFVKTLEQSFFEMKNVLEKNPPET 658
               |:||..||||...| ...:|.|.|.||:....|.|:..:|.:.:.||..::..:|  :||.|
Frog   744 AGGGFGPVADDGYGVSYIFAGENLITLHISSKFSSPETNSHRFGQRICQSMRDLAQLL--SPPVT 806

Fly 659 658
Frog 807 806

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CRAT	NP_001287195.1	Carn_acyltransf	74..648	CDD:279140	191/624 (31%)
cpt1b	XP_012822209.2	CPT_N	39..85	CDD:406797
cpt1b	XP_012822209.2	Carn_acyltransf	209..797	CDD:395612	191/623 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D559299at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010