Protein Alignment CRAT and Crot

DIOPT Version :10

• Sequence 1: NP_649650.2
• Gene: CRAT / 40787
• FlyBaseID: FBgn0037440
• Length: 662
• Species: Drosophila melanogaster
• Sequence 2: NP_076222.1
• Gene: Crot / 74114
• MGIID: 1921364
• Length: 612
• Species: Mus musculus
• Alignment Length: 606
• Identity: 193/606 - (31%)
• Similarity: 306/606 - (50%)
• Gaps: 48/606 - (7%)

  Fly    71 QPNLLKYHVLPLEETLNRFMTTVEPLLTPEEFQRQKGITSEFLKKQGRELQLLLEETGSKEKNWL 135
            |.:|....|..|||:|.:::.:|:|....:|:::.:.|..:|.:..|:.|...|.|....::|||
Mouse    17 QDSLPSLPVPALEESLKKYLESVKPFANEDEYKKTEEIVQKFQEGAGKRLHQKLLERARGKRNWL 81

  Fly   136 AHRWLKAAYLTYRDPVTV---FVSPGMTFPKQNFRDSR--AFVDYTARVIYGLGEFNDMVHANKI 195
            ...||..|||..|.|..:   ||.|...|  :::..:|  ..::..:.:::....:..::...|:
Mouse    82 EEWWLNVAYLDVRIPSQLNVNFVGPCPHF--EHYWPAREGTQLERGSMMLWHNLNYWQLLRREKL 144

  Fly   196 PIVKMGKNELDNSQFGKVFGTCRIPRRGTDEIV--YNPDSD-----YVVVIYKNHFYQLKIYSKE 253
            |:.|.|...||.:||..:|.||::|....|.|:  :..:|:     ::.|:.:...:...:. .|
Mouse   145 PVHKSGNTPLDMNQFRMLFSTCKVPGITRDSIMNYFKTESEGHCPTHIAVLCRGRAFVFDVL-HE 208

  Fly   254 GKLIAAPCLAAQLENIVLK--ETQVGVPYGILTTDSRDNWAEAYEYLVE-TPGNRDALKTIQGAL 315
            |.||..|.|..||..|..|  ...||.....||::.|..||:|.|||:. .|.|...|:.||.:|
Mouse   209 GCLITPPELLRQLTYIHKKCSNEPVGPSIAALTSEERTRWAKAREYLISLDPENLTLLEKIQTSL 273

  Fly   316 FTVSLDEGTILKEGEETDELILSLIHGSGSKINSGNRWMDKTIQLVVNPNGNVGFTYEHSPAEGQ 380
            |..|:::.:.....||..::...|:.|..|.     ||.||:..|:...||..|...:|:|.:..
Mouse   274 FVYSIEDSSPHATPEEYSQVFEMLLGGDPSV-----RWGDKSYNLISFANGIFGCCCDHAPYDAM 333

  Fly   381 PIAMMMDYVVQKMKEDPS--FGQSGSQDFAPAQKIQFSSSNKSLEKSLNVAQENVD--KLADALQ 441
            .:..:..||.:::.|...  .|....:|....:::.|:...|.|.   :|:|....  |.|..||
Mouse   334 VMVNIAHYVDERVLETEGRWKGSEKVRDIPLPEELVFTVDEKILN---DVSQAKAQHLKAASDLQ 395

  Fly   442 MKVLKFNGFGKDFIKKQRLGPDSFVQMALQLAFYKMHSEPPAQYESAHLRIFDGGRTETIRSCSN 506
            :....|..|||...|::.|.||:|:|:|||||:|::|..|...||:|..|.|..|||||:|||:.
Mouse   396 IAASTFTSFGKKLTKEEALHPDTFIQLALQLAYYRLHGRPGCCYETAMTRYFYHGRTETVRSCTV 460

  Fly   507 ESLAFSRAMQDPNVTDQERAAKLREAVVSHQTYAKLALQGKGVDRHLLGLKLMALEHSKPIPEFF 571
            |::.:.::||||:.:..||..|:.||...|....|....|||.|||||||.|:|.|...|:||.|
Mouse   461 EAVRWCQSMQDPSASLLERQQKMLEAFAKHNKMMKDCSHGKGFDRHLLGLLLIAKEEGLPVPELF 525

  Fly   572 KSPGFVKS---SHFRMSTSQVATKYDAFMGY-------GPATDDGYACCYNPRDNDIILAISAWR 626
            :.|.|.:|   .:|.:|||.|        ||       .|...:||...|:.||:..::|.|:||
Mouse   526 EDPLFSRSGGGGNFVLSTSLV--------GYLRVQGVVVPMVHNGYGFFYHIRDDRFVVACSSWR 582

  Fly   627 HCPITDHLKFVKTLEQSFFEM 647
            .||.||..|.|:.:..:|.:|
Mouse   583 SCPETDAEKLVQMIFHAFHDM 603

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CRAT	NP_649650.2	Carn_acyltransf	79..642	CDD:459926	189/591 (32%)
Crot	NP_076222.1	Carn_acyltransf	23..596	CDD:459926	189/591 (32%)
		Microbody targeting signal. /evidence=ECO:0000255	610..612