DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CRAT and crata

DIOPT Version :9

Sequence 1:	NP_001287195.1	Gene:	CRAT / 40787	FlyBaseID:	FBgn0037440	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	NP_001005587.1	Gene:	crata / 449545	ZFINID:	ZDB-GENE-040927-17	Length:	631	Species:	Danio rerio

Alignment Length:	644	Identity:	230/644 - (35%)
Similarity:	370/644 - (57%)	Gaps:	27/644 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 GKLLWNLTKNSLAQQSPNGIAKKVLPASSYSTVQKTIPLEQPNLLKYHVLPLEETLNRFMTTVEP 95
            |.|...:.|..:.:  |:|:.|.|    |.:.|.......|..|.|..|.||::|.:|::..::|
Zfish     3 GILARTMVKAGMVK--PSGLVKPV----SVTRVTGRYLTHQEGLPKLPVPPLKQTCDRYLAALDP 61

  Fly    96 LLTPEEFQRQKGITSEFLKK--QGRELQLLLEETGSKEKNWLAHRWLKAAYLTYRDPVTVFVSPG 158
            ::.|||....:.:..:|.|.  .|..||..||...:|..|||:..||:.|||.||.||.|..|||
Zfish    62 IVDPEELNHTRKLLEDFQKPGGVGERLQKGLESRAAKLNNWLSDWWLQTAYLDYRMPVVVHSSPG 126

  Fly   159 MTFPKQNFRDSRAFVDYTARVIYGLGEFNDMVHANKIPIVKMGKNELDNSQFGKVFGTCRIPRRG 223
            :..|:..|.|.:..:.|.|::|.|:.:|..|:....:|:..:|...|...|:.:|..:||||...
Zfish   127 VVLPRMEFSDRQGQMRYAAKLIAGVLDFKSMIDNETLPLEYLGGKPLCMHQYYQVLSSCRIPGTK 191

  Fly   224 TDEIV-YNPD---SDYVVVIYKNHFYQLKIYSKEGKLIAAPCLAAQLENIVLKETQVG-VPYGIL 283
            .|.:| |..|   |.::.|::...|:.|.:|:.:|..:....:..|||.|.....|.. .|.|||
Zfish   192 RDTVVNYAMDKRPSTHITVVHNFQFFVLDVYNSDGTPLTVDQIYIQLEKIWNSSLQTNKEPIGIL 256

  Fly   284 TTDSRDNWAEAYEYLVETPGNRDALKTIQGALFTVSLDEGTILKEGEETDELI-----LSLIHGS 343
            |::.|::|.:||..|::...|:::::.||.::|||.||    ......:|::.     :.::||.
Zfish   257 TSNHRNSWGKAYNNLIKDKTNKESVRAIQKSIFTVCLD----APMPRASDDMYRTRAGVQMLHGG 317

  Fly   344 GSKINSGNRWMDKTIQLVVNPNGNVGFTYEHSPAEGQPIAMMMDYVVQKMKEDPSFGQSGSQDFA 408
            ||:.||||||.|||:|.::..:|..|..|||:||||.||..::|:||:.||:. ...::......
Zfish   318 GSRWNSGNRWFDKTLQFIIGEDGTCGLIYEHAPAEGPPIVSILDHVVEYMKKS-EMVRTPMVPLR 381

  Fly   409 PAQKIQFSSSNKSLEKSLNVAQENVDKLADALQMKVLKFNGFGKDFIKKQRLGPDSFVQMALQLA 473
            ..||::|:.: ..::|.:..|::|::.:...|.::|..|..|||:|.|.|::.||:|:|||||||
Zfish   382 MPQKLRFNIT-PEIKKDIEDAKQNMNIMVHDLDLRVNVFTHFGKNFPKSQKMSPDAFIQMALQLA 445

  Fly   474 FYKMHSEPPAQYESAHLRIFDGGRTETIRSCSNESLAFSRAMQDPNVTDQERAAKLREAVVSHQT 538
            :|:::......||||.||:|..|||:||||.|::|.:|.:||.||...:.|:.|.|.:||.:|::
Zfish   446 YYRIYKRCCPTYESASLRMFRLGRTDTIRSASSDSASFVKAMDDPVKHNTEKVALLDKAVKAHRS 510

  Fly   539 YAKLALQGKGVDRHLLGLKLMALEHSKPIPEFFKSPGFVKSSHFRMSTSQVATKYDAFMGYGPAT 603
            |..:|::|:.:|||||||||.|:|....:||.|....:..:.|:.:|||||..|.|..|.:||..
Zfish   511 YTDMAIRGQAIDRHLLGLKLQAIEDLAALPEIFMDTSYAVALHYNLSTSQVPAKTDCVMCFGPVV 575

  Fly   604 DDGYACCYNPRDNDIILAISAWRHCPITDHLKFVKTLEQSFFEMKNVLEKNPPETKSKL 662
            .|||..||||.|..|..|:||:..|..|:.::..:.||.:..:|:.:||:.|   ::||
Zfish   576 PDGYGVCYNPMDTHINFAVSAFNSCQDTNAVRLAQGLEDALLDMRTLLEQTP---RAKL 631

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CRAT	NP_001287195.1	Carn_acyltransf	74..648	CDD:279140	214/585 (37%)
crata	NP_001005587.1	Carn_acyltransf	40..620	CDD:279140	214/585 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594979
Domainoid	1	1.000	403	1.000	Domainoid score	I686
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H598
Inparanoid	1	1.050	414	1.000	Inparanoid score	I1807
OMA	1	1.010	-	-		QHG59015
OrthoDB	1	1.010	-	-		D167256at33208
OrthoFinder	1	1.000	-	-		FOG0001049
OrthoInspector	1	1.000	-	-		otm24513
orthoMCL	1	0.900	-	-		OOG6_102174
Panther	1	1.100	-	-	LDO	PTHR22589
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2058
SonicParanoid	1	1.000	-	-		X630
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	13.940